The Lead

Pipelines Under Pressure Take New Paths

May 15, 2012 2:58 pm | by Ted Agres, Contributing Editor | Articles | Comments

In order to foster innovation, reduce costs, and halt the erosion of revenue, major pharmaceutical companies are exploring a range of new and emerging research arrangements.

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DDD Update

Daily news and top headlines for drug research professionals

Natural Product Purification of Lycopene and β‐Carotene Using Flash Column Sample Clean‐up Prior to High Pressure Normal Phase Chromatography on the Gilson PLC 2020

May 16, 2012 3:25 pm | White Papers | Comments

Purifying low level compounds, such as those typically isolated from natural products, is an area of growing interest for the purpose of discovering new chemical entities.

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Beatson Institute and Carestream Partner

May 16, 2012 11:25 am | News | Comments

The Beatson Institute for Cancer Research and Carestream Molecular Imaging have signed a 5-year partnership agreement to support the development of novel preclinical imaging approaches.

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Nanobiotix Working with Thomas Jefferson

May 16, 2012 11:19 am | News | Comments

Nanobiotix and Thomas Jefferson University have entered into a research collaboration to accelerate the development of Nanobiotix’ lead compound NBTXR3.

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Cause of Genetic Condition Unmasked

May 16, 2012 11:09 am | News | Comments

Scientists have identified the genetic cause of a birth defect known as Hamamy syndrome, a condition which causes defects in the heart, bone, blood, and reproductive cells.

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Key Genes Help ID Schizophrenia Risk

May 16, 2012 10:59 am | News | Comments

A research team has identified a group of genes most associated with schizophrenia that together can generate a score indicating whether an individual is at higher or lower risk.

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PLX Cells Improve Diastolic Dysfunction

May 16, 2012 10:42 am | News | Comments

Pluristem Therapeutics Inc. announced that cardiac function in a diabetic-induced diastolic dysfunction in animals improved following PLacental eXpanded administration.

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ACH-3102 on the Fast Track

May 16, 2012 10:36 am | News | Comments

Achillion Pharmaceuticals Inc. announced the receipt of Fast Track designation from the U.S. Food and Drug Administration for ACH-3102 for the treatment of chronic hepatitis C.

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GSK Increases Theravance Holdings

May 16, 2012 10:29 am | News | Comments

British drug maker GlaxoSmithKline PLC has closed on a deal that boosts its interest in biotechnology company Theravance Inc. by 10 million shares.

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FDA Approves BMS Plant

May 16, 2012 10:04 am | News | Comments

Bristol-Myers Squibb Co. said the Food and Drug Administration approved a new manufacturing plant where the company will produce its rheumatoid arthritis drug Orencia.

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Piramal to Buy DRG

May 16, 2012 10:00 am | Articles | Comments

India's Piramal Healthcare said it will buy Decision Resources Group, a U.S. healthcare information company, for $635 million, as it slowly taps its cashpile for overseas acquisitions.

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Faster Pharmacokinetics

May 15, 2012 12:45 pm | by Mike May, Contributing Editor | Articles | Comments

Pharmacokinetics plays a crucial role in a compound’s efficacy and safety and to characterize the pharmacokinetics of a compound, accurate measurements are needed.

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Measure More, Test Once

May 15, 2012 12:22 pm | by Rick Wiese, PhD, R&D Manager; EMD Millipore, St. Charles, Mo. | Articles | Comments

While traditional multiplexed immunoassays have advanced scientific understanding of intracellular signaling, a number of challenges remain.

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Sealing Film

May 15, 2012 11:59 am | Products | Comments

96-Well PTFE sealing film from J.G. Finneran Associates is designed to seal samples in microplates during high-throughput bioanalytical studies.

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Microplate Washer

May 15, 2012 11:52 am | Products | Comments

BioTek introduces the 405 LS Series microplate washer for 96- and 384-well microplate washing. This microplate washer is especially suited for robotic installations or remote operation.

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Electronic Pipette

May 15, 2012 11:44 am | Articles | Comments

Eppendorf has introduced its electronic pipette, the Eppendorf Xplorer plus. The Eppendorf Xplorer is specially designed for users working with complex or long pipetting series.

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