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FDA Approves Bristol-Myers’s Opdivo to Treat Kidney Cancer

November 24, 2015 | by Stephanie Guzowski, Editor | News | Comments

Bristol-Myers Squibb has received approval from the FDA for the expanded use of its immuno-oncology drug, Opdivo (nivolumab) — this time, to treat advanced renal cell carcinoma (RCC), a form of kidney cancer. The approval happened just one week after the FDA accepted BMS’s filing for priority review. Read more...

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DDD Update

Daily news and top headlines for drug research professionals

Experts Foresee Big Premium Increases for Medicare Drug Plan

November 24, 2015 12:21 pm | by Ricardo Alonso-Zaldivar, Associated Press | News | Comments

With time running out on open enrollment season, many seniors are facing sharply higher premiums for Medicare's popular prescription drug program. The reason: rising drug costs have overtaken a long stretch of stable premiums. Read more...


Investigational Drug May Prevent Life-threatening Muscle Loss in Advanced Cancers

November 24, 2015 12:14 pm | by Ohio State University Medical Center | News | Comments

New data describes how an experimental drug can stop life-threatening muscle wasting (cachexia) associated with advanced cancers and restore muscle health. Read more...


Research Team Describes Novel Tumor Treatment

November 24, 2015 12:03 pm | by Virginia Tech | News | Comments

In the first published results from a $386,000 National Cancer Institute grant awarded earlier this year, a paper by Scott Verbridge and Rafael Davalos in Scientific Reports has been published. Read more...


EU Grants Marketing Authorization for Gilead's Single-Tablet Regimen for HIV-1

November 24, 2015 8:00 am | News | Comments

This marketing authorization is based on a Phase 3 HIV clinical program in more than 3,500 patients across 21 countries. Read more...


Exploring the Causes of Cancer

November 24, 2015 7:45 am | by Queens University | News | Comments

RET is a protein that plays an important role in kidney and nerve development and is also important in many human cancers including thyroid, breast and pancreas. Read more...


FDA Approves BI's Pradaxa for Prophylaxis of DVT, PE after Hip Replacement Surgery

November 24, 2015 7:30 am | News | Comments

The FDA approval is based on the results of two randomized, double-blind, phase III trials in patients undergoing total hip replacement. Read more...


Tuberculosis: Daily Antibiotics Recommended to Prevent Resistant Strains

November 24, 2015 7:15 am | by University of Michigan | News | Comments

A computer model of tuberculosis has shown that approved treatments prescribing antibiotic doses once or twice a week are more likely to lead to drug resistant strains than are daily antibiotic regimens. Read more...


New Research Suggests Novel Route in Fight Against Cancer

November 24, 2015 7:00 am | by University of Surrey | News | Comments

Scientists from the University of Surrey have uncovered a collection of important proteins that carry out and regulate critical biological processes. Read more...


Roche Releases Positive Early Data on Melanoma Drug

November 23, 2015 11:34 am | by Stephanie Guzowski, Editor | News | Comments

The Swiss pharmaceutical company Roche announced on Monday its results from a Phase 1b trial of investigational cancer immunotherapy candidate atezolizumab in treating advanced melanoma. Read more...


Ebola Response was ‘$5 Billion Scramble’ Leaving Thousands Dead

November 23, 2015 10:25 am | by Seth Augenstein, Digital Reporter | News | Comments

As the last vestiges of the Ebola outbreak are being eradicated in West Africa, health officials are evaluating how agencies across the world responded to the outbreak which began two years ago, and killed more than 11,000 people. Read more...


Personalized Drug Screening on Horizon for Multiple Myeloma Patients

November 23, 2015 10:20 am | by Washington University in St. Louis | News | Comments

A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer. The process, developed by scientists at Washington University School of Medicine​ in St. Louis, also may aid patients with leukemia or lymphoma. Read more...


Inflammation Linked to Weakened Reward Circuits in Depression

November 23, 2015 10:15 am | by Emory Health Sciences | News | Comments

About one third of people with depression have high levels of inflammation markers in their blood. New research indicates that persistent inflammation affects the brain in ways that are connected with stubborn symptoms of depression, such as anhedonia, the inability to experience pleasure. Read more..


New $710-A-Day Drug Saves Lives But Strains State Budgets

November 23, 2015 10:07 am | by Dave Gram, Associated Press | News | Comments

A newly approved drug is being hailed as a major advance in treatment of cystic fibrosis, a life-threatening genetic disease that clogs the lungs with mucus and forces patients to struggle to breathe. But it comes with a punishing price tag - about $710 per patient per day. Read more...


Pfizer, Allergan Agree to $160B Merger

November 23, 2015 9:17 am | by Ryan Bushey, Associate Editor | News | Comments

This new entity would be the world's biggest drug maker. Read more...


Independent Panel of Global Experts Calls for Critical Reforms to Prevent Future Outbreaks

November 23, 2015 8:15 am | by London School of Hygiene & Tropical Medicine | News | Comments

The report offers 10 major reform proposals to prevent future catastrophes. Read more...



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