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Brain Disease Similar to Mad Cow is First to be Linked to Rogue Proteins in 50 Years

September 2, 2015 | by Seth Augenstein, Digital Reporter | News | Comments

Multiple System Atrophy, a brain disorder, is caused by a newly-discovered prion linking it to incurable diseases like mad cow and Creutzfeldt-Jakob disease, according to new research. Read more...

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DDD Update

Daily news and top headlines for drug research professionals

Helsinn: Exclusive Agreement With Mundipharma for Distribution of Anamorelin

September 3, 2015 4:26 pm | News | Comments

Helsinn, the Swiss Group focused on building quality cancer care, and Mundipharma, today announce that they have entered into distribution, license and supply agreements granting exclusive rights to anamorelin in Switzerland and Liechtenstein. Read more...

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Study Finds Increased Risk of MGUS in Vietnam Vets Exposed to Agent Orange

September 3, 2015 4:23 pm | News | Comments

A study that used stored blood samples from U.S. Air Force personnel who conducted aerial herbicide spray missions of Agent Orange during the Vietnam war found a more than 2-fold increased risk of the precursor to multiple myeloma known as monoclonal gammopathy of undetermined significance (MGUS), according to an article published online by JAMA Oncology. Read more...

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Using Cell Phones to Track Disease Outbreaks

September 3, 2015 4:14 pm | by Greg Watry, Digital Reporter | News | Comments

Princeton and Harvard Univ. researchers have found mobile phone data can help predict seasonal disease patterns. Read more...

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Aspirin Could Hold the Key to Supercharged Cancer Immunotherapy

September 3, 2015 4:11 pm | by Cancer Research UK | News | Comments

Giving cancer patients aspirin at the same time as immunotherapy could dramatically boost the effectiveness of the treatment, according to new research published in the journal Cell Thursday. Read more...

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New Mechanism Discovered Behind Infant Epilepsy

September 3, 2015 4:04 pm | by Karolinska Institutet | News | Comments

Scientists at Karolinska Institutet and Karolinska University Hospital in Sweden have discovered a new explanation for severe early infant epilepsy. Mutations in the gene encoding the protein KCC2 can cause the disease, hereby confirming an earlier theory. The findings are being published in the journal Nature Communications. Read more...

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Team Developing New Drug Against Leading Causes of Death — Sepsis and ARDS

September 3, 2015 3:58 pm | by Queen's University | News | Comments

Scientists at Queen's University Belfast are developing a potential revolutionary new treatment for Sepsis and Acute Respiratory Distress Syndrome (ARDS), which are among the leading causes of death in hospitalized patients in the UK. Read more...

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Early Study Points to Calcium-Regulating Protein in Alzheimer’s

September 3, 2015 2:12 pm | by Stephanie Guzowski, Editor | News | Comments

The way in which calcium is regulated in the body plays a vital role in the brain’s aging — and by extension, susceptibility to neurological diseases such as Alzheimer’s, ALS, Parkinson’s and vascular dementia, finds a recent study published in the Journal of Neuroscience. Read more...

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Drug for Fungal Infections in Lung Transplant Recipients Increases Risk for Cancer, Death

September 3, 2015 9:54 am | by University of California, San Francisco | News | Comments

Voriconazole, a prescription drug commonly used to treat fungal infections in lung transplant recipients, significantly increases the risk for skin cancer and even death, according to a new study by UC San Francisco researchers. The team recommends physicians consider patient-specific factors that could modify the drug’s risks and benefits, when providing care. Read more...

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Researchers Report Long-Term Remissions in First Personalized Cell Therapy Trial

September 3, 2015 9:50 am | by University of Pennsylvania School of Medicine | News | Comments

Eight of 14 patients in the first trial of the University of Pennsylvania's personalized cellular therapy for chronic lymphocytic leukemia (CLL) responded to the therapy, with some complete remissions continuing past four and a half years. Read more...

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Legionnaires' Outbreaks Not Unusual in Summer & Early Fall

September 3, 2015 9:30 am | by Lindsay Tanner, AP Medical Writer | News | Comments

Legionnaires' disease has been reported in a handful of states this summer, leading to 19 deaths and more than 100 illnesses. The unrelated cases are part of a typical pattern seen with a disease that tends to appear in warm weather and is mostly dangerous for people who already are sick or weakened. Read more...

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Scientists Move Closer to Curing Eye Disorder

September 3, 2015 8:15 am | by University of Manchester | News | Comments

Scientists have successfully restored the site of laboratory mice suffering from a common cause of blindness in people. Read more...

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Ballooning Platelets and the Future of Anti-Thrombotic Drugs

September 3, 2015 8:00 am | by University of Bristol | News | Comments

Platelets play a central role in stopping bleeding (haemostasis) and causing blockages in arteries (arterial thrombosis), particularly in coronary artery disease. Read more...

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2 Cases of Polio Found in Ukraine, Caused by Mutated Virus

September 3, 2015 7:30 am | by The Associated Press | News | Comments

The World Health Organization said officials have found two children stricken by polio in Ukraine, the country's first cases of the paralytic disease in nine years. Read more...

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Antisense RNAi Therapeutics Deals Value Approach $5.6B in Landmark 2014

September 3, 2015 7:15 am | by Adam Dion, MS, Senior Industry Analyst for GlobalData | News | Comments

Three mergers and acquisitions worth $1.2 billion, as well as record highs for licensing and capital raisings, helped to fuel deals in 2014. Read more...

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British Man Shedded Mutated Polio Strain for 28 Years

September 3, 2015 7:00 am | by Ryan Bushey, Associate Editor | News | Comments

Researchers performing the study found the mutated virus after analyzing more than 100 stool samples from the patient. Read more...

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