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DDD Update

Daily news and top headlines for drug research professionals

HIV Drug Dosage May Be Ineffective for African-Americans

August 28, 2014 2:00 pm | News | Comments

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study suggests. The initial dosing studies, completed before the drug was licensed in 2007, included mostly European-Americans, who generally lack a protein that is key to removing maraviroc from the body. Read more...

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Researchers Investigating New MS Treatment

August 28, 2014 2:00 pm | News | Comments

A new treatment under investigation for multiple sclerosis (MS) is safe and tolerable in Phase 1 clinical trials, according to a new study. The Phase 1 studies were the first to test the drug candidate in humans. Read more...     

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High-Performance, Multi-Position Reaction Block

August 28, 2014 10:24 am | Product Releases | Comments

The DrySyn MULTI from Asynt converts any standard hotplate stirrer into a high performance reaction block accommodating 3 round-bottomed flasks or up to 12 reactions in tubes or vials.

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ChIP Sequencing Kit for NGS

August 28, 2014 10:17 am | Product Releases | Comments

The ChIP sequencing assay kit from Porvair Sciences extends the benefits of their proprietary Chromatrap solid state ChIP technology to preparation of purified Chromatin for the generation of sequencing libraries.

Fraction Collection Storage Solution

August 28, 2014 10:08 am | Product Releases | Comments

A complete storage solution for HPLC fractions is available from Porvair Sciences, comprised of the company's 2ml round deep well microplate and high integrity cap mat seals.

Two-Drug Combo Speeds Wound Healing, Reduces Scar Tissue

August 28, 2014 9:53 am | News | Comments

A combination of two drugs already approved by the U.S. Food and Drug Administration for different applications reduces wound healing time by one-quarter and significantly decreases scar tissue in mice and rats, researchers report. Read more...     

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FDA Approves Generic Megace from TWi

August 28, 2014 9:45 am | News | Comments

TWi Pharmaceuticals Inc. announced that it has received final approval from the FDA on its Abbreviated New Drug Application for megestrol acetate 125mg/ml oral suspension, the generic equivalent to Par Pharmaceutical's Megace ES. Read more...   

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Daiichi Sankyo Signs Hep B Vaccine Agreement

August 28, 2014 9:40 am | News | Comments

Daiichi Sankyo Co. Ltd. announced that it has signed a cooperative sales agreement with The Chemo-Sero-Therapeutic Research Institute  for its recombinant adsorbed hepatitis B vaccine (yeast-derived), Bimmugen. Read more...       

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UN: Ebola Cases Could Reach 20,000

August 28, 2014 9:34 am | by John Heilprin and Krista Larson | News | Comments

The Ebola outbreak in West Africa eventually could exceed 20,000 cases, more than six times as many as are now known, the World Health Organization said Thursday. Read more...                      

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Allergan Sets Date for Special Shareholder Meeting

August 27, 2014 3:28 pm | by The Associated Press | News | Comments

Botox maker Allergan Inc. has set a date for a special meeting at which its shareholders will consider replacing most of its board, but it doesn't want the main proponents of that move to participate. Read more...           

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FDA Clears Asterias to Begin Stem Cell Trial

August 27, 2014 3:08 pm | News | Comments

Asterias Biotherapeutics Inc. has received clearance from the FDA to initiate a Phase 1/2a clinical trial of its product, AST-OPC1, in patients with complete cervical spinal cord injury. Read more...               

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Marijuana Compound May Slow, Halt Alzheimer’s

August 27, 2014 3:00 pm | News | Comments

Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer’s disease, a new study says. Read more...                   

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Potential Therapy for Sudan Ebola Strain May Contain Future Outbreaks

August 27, 2014 2:45 pm | News | Comments

Ebola is a rare, but deadly disease that exists as five strains, none of which have approved therapies. One of the most lethal strains is the Sudan ebolavirus (SUDV). In a new study, researchers report a possible therapy that could someday help treat patients infected with SUDV. Read more...

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Amgen Heart Failure Drug Gets Priority Review

August 27, 2014 2:32 pm | News | Comments

Amgen announced the FDA has granted priority review designation for ivabradine for the treatment of chronic heart failure (HF). Ivabradine is an oral drug that inhibits the If current ("funny" current) in the sinoatrial node. Read more...   

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Compound Suppresses Binge Eating in Mice

August 27, 2014 2:26 pm | News | Comments

Researchers found that the hormone estrogen can specifically trigger brain serotonin neurons to inhibit binge eating, which affects about 5 to 10 percent of U.S. adults, in female mice. Read more...               

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