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DDD Update

Daily news and top headlines for drug research professionals

Light — Not Pain-Killing Drugs — Used to Activate Brain’s Opioid Receptors

May 4, 2015 11:54 am | by Washington University in St. Louis | News | Comments

Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp down the body’s pain response. But now, neuroscientists at Washington University School of Medicine in St. Louis have found a way to activate opioid receptors with light. Read more...

Foreign Antibodies Mobilize Immune System to Fight Cancer, Researchers Find

May 4, 2015 11:48 am | by Stanford University | News | Comments

A mouse’s T cells can be primed to attack and eliminate a malignant tumor by injecting antibodies from another mouse with resistance to the tumor, as well as by activating certain signaling cells, a study has found. Read more...

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Improving the Chance of Success When an Outcome Can’t Be Predicted

May 4, 2015 9:07 am | by Matthew Segall, CEO, Optibrium Ltd., Cambridge, UK | Articles | Comments

Predictive models are widely used in drug discovery, with the goal of quickly identifying compounds that will achieve the many requirements of a successful drug. In addition to predicting target potency, a wide range of other properties can be predicted, including absorption, distribution, metabolism and elimination (ADME), toxicity and pharmacokinetics (PK). Read more..

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New Meds Help Drugmakers Weather Strong Dollar, Other Issues

May 4, 2015 9:04 am | by Linda A. Johnson, AP Business Writer | News | Comments

Revenue from important new medicines for various cancers, hepatitis C and more helped top U.S. drugmakers weather unfavorable currency exchange rates and other challenges. Read more...

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U.S. Shuts Down Ebola Treatment Center in Liberia

May 4, 2015 8:59 am | by The Associated Press | News | Comments

American officials are shutting down a special treatment unit they set up in Liberia at the height of the Ebola crisis last year. Read more...

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Study Points Way Forward for Retinal Disease Gene Therapy

May 4, 2015 8:57 am | by National Eye Institute | News | Comments

Gene therapy for LCA, an inherited disorder that causes vision loss starting in childhood, improved patients’ eyesight and the sensitivity of the retina within weeks of treatment. Read more...

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Performance Enhancing Drugs Decrease Performance

May 4, 2015 8:51 am | by University of Adelaide | News | Comments

Doping is damaging the image of sport without benefiting athletes’ results. Read more...

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Researchers Closer to Being Able to Change Blood Types

May 4, 2015 8:48 am | by University of British Columbia | News | Comments

What do you do when a patient needs a blood transfusion but you don’t have their blood type in the blood bank? It’s a problem that scientists have been trying to solve for years but haven’t been able to find an economic solution until now. Read more...

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Progress Towards a New Asthma Treatment

May 4, 2015 8:42 am | by University of Queensland | News | Comments

Researchers are developing a new asthma treatment that targets the underlying cause of asthma, rather than just the symptoms. Read more...

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Pakistani National Sold Drugs for Incurable Conditions, FDA Charges

May 1, 2015 4:28 pm | by Seth Augenstein, Digital Reporter | News | Comments

A Pakistani national has been indicted on fraud and other charges, according to federal authorities, after he allegedly sold bogus drugs to cure serious diseases — some of which are incurable. Read more...

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Majority of Older Adults Willing to be Screened by Phone for Dementia: Study

May 1, 2015 12:15 pm | News | Comments

Nearly two-thirds of older adults were willing to undergo telephone screening for dementia, according to a new study from the Indiana University Center for Aging Research and the Regenstrief Institute. Willingness to be screened by phone did not differ by sex, age or race. Read more...

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Biotech Workers Win $58 Million Lottery Drawing, to Split Prize

May 1, 2015 12:06 pm | by Seth Augenstein, Digital Reporter | News | Comments

A group of 16 biotech workers at an office in Manhattan won a $58 million Mega Millions jackpot drawing this week, according to multiple reports. Read more...

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Apple's ResearchKit - The Real Impact on Clinical Trials

May 1, 2015 11:57 am | by Merrilyn Datta, Ph.D., President and General Manager, Definiens | Articles | Comments

Apple recently released news about its new ResearchKit, a medical platform that intends to turn the iPhone and HealthKit into diagnostic tools. The technology, which enables researchers to create apps that gather new types of health data from users who opt-in, has gotten quite a bit of attention throughout the healthcare and technology communities. Read more...

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Braeburn Expands Pipeline to Include Two Schizophrenia Treatments

May 1, 2015 11:47 am | News | Comments

Braeburn Pharmaceuticals announced today that it has expanded its current therapeutic focus beyond addiction and pain to include schizophrenia and other serious psychiatric disorders. Read more..

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Bayer's Contraception Safe, Effective: 5-Year Follow-Up Study

May 1, 2015 11:42 am | News | Comments

Bayer HealthCare announced today that a study published online this week in The Journal of Minimally Invasive Gynecology reinforces findings from previous clinical studies that support the effectiveness and safety of the Essure inserts and procedure for hysteroscopic sterilization, or permanent birth control. Read more...

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