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DDD Update

Daily news and top headlines for drug research professionals

Enamine, Sanofi Extend Early Drug Discovery Collaboration

December 18, 2014 9:06 am | News | Comments

Enamine and Sanofi extend partnership for early drug discovery. Read more...                               

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GSK Shingles Vaccine Hits Goal in Major Study

December 18, 2014 9:02 am | News | Comments

GSK announced that a pivotal phase 3 study to assess the efficacy of HZ/su, an investigational vaccine for the prevention of shingles, has met its primary endpoint. Read more...                                 

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New Generation of Cancer Drugs Granted European Approval

December 18, 2014 8:26 am | by University of Cambridge | News | Comments

A new drug for ovarian cancer has become the first of new class of drugs to be granted approval anywhere in the world. Read more...                      

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Fresh Setback For Efforts to Cure HIV Infection

December 18, 2014 8:12 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Researchers are reporting another disappointment for efforts to cure infection with the AIDS virus. Read more...                         

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Chikungunya Virus Shuts Down Infected Cells

December 17, 2014 4:59 pm | by Wageningen University | News | Comments

Researchers from Wageningen University, part of Wageningen UR, in collaboration with colleagues from Leiden University and a research team in Australia, have revealed how chikungunya virus blocks essential processes in infected cells that normally would keep the virus under control. Read more...

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Despite Risks, Benzodiazepine Use Highest in Older People

December 17, 2014 4:50 pm | by NIH | News | Comments

Prescription use of benzodiazepines — a widely used class of sedative and anti-anxiety medications — increases steadily with age, despite the known risks for older people, according to a comprehensive analysis of benzodiazepine prescribing in the United States. Read more...

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Stem Cell Prompting Deadly Fibrosis Found

December 17, 2014 4:35 pm | by Cynthia Fox, Science Writer | Articles | Comments

Some 45% of deaths are caused by fibrosis (scar tissue) diseases, including idiopathic pulmonary fibrosis, cirrhosis, and heart and kidney failure. But a Harvard University group reports in Cell Stem Cell they have discovered a key cause of that fibrosis: a stem-cell-like perivascular cell called Gli1+, found in blood vessels. Read more...

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Study: Removing Clot Helps Limit Stroke Disability

December 17, 2014 2:25 pm | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

A new treatment has been shown to limit the damage from a common type of stroke. Read more...                           

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Rio Organizers Create 'Super Bacteria' Task Force

December 17, 2014 2:12 pm | by Jenny Barchfield - Associated Press | News | Comments

Brazilian organizers of the 2016 Olympics are creating a task force to deal with a so-called "super bacteria" discovered in Olympic sailing waters. Read more...                 

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Napster Co-Founder Makes Investment in Allergy Research

December 17, 2014 2:03 pm | by Olga R. Rodriguez - Associated Press | News | Comments

The former Facebook president said he wants to help find a lasting cure to allergies. Read more...                           

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Emerging Markets Gain New Prominence as Innovation, Development Hotspots

December 17, 2014 12:52 pm | by Roger Humphrey, Executive Managing Director, Life Sciences Americas, JLL | Articles | Comments

Patent origin location has become the latest way patent applications can inform business strategy, and recent analysis shows where innovation hubs are on the rise. The United States and Europe have enjoyed long deep-seated roots as the leaders of high-value aspects of the biopharmaceutical development cycle, such as new product research and development (R&D). Read more...

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New Insight Into How Motor Neurons in Brain Die During ALS

December 17, 2014 12:33 pm | News | Comments

Researchers look to understand the causes of amyotrophic lateral sclerosis (ALS), in the hope of finding new ways to treat the disease. A new study published online in the Cell Press journal Neuron shows that a common gene mutation in ALS generates a deadly protein that may cause the damage in the brain that leads to ALS. Read more...

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Ohio House to Consider Lethal Injection Drug Bill

December 17, 2014 12:22 pm | News | Comments

The names of companies that provide Ohio with lethal injection drugs would be shielded under a proposal the state House is poised to vote on Wednesday. Read more...                                        

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Occasional Heroin Use May Worsen HIV Infection

December 17, 2014 12:15 pm | News | Comments

Researchers at Yale and Boston University and their Russian collaborators have found that occasional heroin use by HIV-positive patients may be particularly harmful to the immune system and worsens HIV disease, compared to persistent or no heroin use. Read more...

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PDI Announces Launch of NGS Test for Cancer Risk Assessment

December 17, 2014 12:07 pm | News | Comments

PDI, Inc. announced that its molecular diagnostics subsidiary, Interpace Diagnostics, has launched its new next-generation sequencing (NGS) ThyGenX test to assist physicians in distinguishing between benign and malignant genotypes in indeterminate thyroid nodules.  Read more...

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