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DDD Update

Daily news and top headlines for drug research professionals

Freshly Squeezed Vaccines

May 22, 2015 8:39 am | by MIT | News | Comments

Researchers have shown that they can use a microfluidic cell-squeezing device to introduce specific antigens inside the immune system’s B cells. Read more...

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Shining a New Light on The Immune System

May 22, 2015 8:24 am | by University of St. Andrews | News | Comments

Researchers used a light scattering technique to identify important types of white blood cells. Read more...

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Janssen, Achillion Pharmaceuticals Team Up to Fight Hepatitis C

May 22, 2015 8:24 am | News | Comments

A key objective of the collaboration will be to develop a short-duration, highly effective, pan-genotypic, oral regimen for the treatment of HCV. Read more...

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CVS Paying $10.4B in Cash for Drug Distributor Omnicare

May 22, 2015 8:23 am | by Tom Murphy, AP Business Writer | News | Comments

CVS Health will pay more than $10 billion for pharmaceutical distributor Omnicare in a deal primed to feed its fast-growing specialty drug business and tap a lucrative and growing market: care for the elderly. Read more...

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Potential New Drug Target for the Treatment of Rheumatoid Arthritis

May 21, 2015 1:40 pm | News | Comments

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints. Read more...

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New Data on Boehringer Ingelheim's COPD Treatment

May 21, 2015 1:30 pm | News | Comments

Boehringer Ingelheim announced new data analyses from the pivotal Phase III TONADO 1&2 studies (NCT01431274/NCT01431287), which explored the efficacy and safety of investigational tiotropium/olodaterol delivered via the Respimat inhaler for chronic obstructive pulmonary disease (COPD) compared to the individual components (tiotropium and olodaterol delivered by the RESPIMAT inhaler) alone. Read more...

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Novartis Announces COPD Phase 3 Results

May 21, 2015 1:23 pm | News | Comments

Today, Novartis announced for the first time detailed results from its phase III EXPEDITION trial program for QVA149 (indacaterol/glycopyrronium) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD). Read more...

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Emmes Announces FDA Clearance of New Medical Device

May 21, 2015 1:18 pm | News | Comments

The Emmes Corporation today announced that the U.S. Food and Drug Administration (FDA) has given marketing clearance for a new device that allows doctors to more accurately assess children's weight without the use of a weight scale. Weight estimates are used in emergency situations and in developing countries where scales may not be available. Read more...

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Injected T Cells from Bone Marrow Treat Multiple Myeloma, Pilot Study Finds

May 21, 2015 1:12 pm | by Stephanie Guzowski, Editor | Articles | Comments

In a first small clinical trial of its kind, researchers harnessed T cells from patients’ own bone marrow to treat multiple myeloma and provide immune protection for up to a year, according to a study published this week in Science Translational Medicine. Read more...

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FDA Proposes to Know More About Antibiotic Use in Animals

May 21, 2015 9:51 am | by Mary Clare Jalonick, Associated Press | News | Comments

The Food and Drug Administration is moving to collect more information on antibiotics used in animals that become meat. It's an effort to stem antibiotic-resistant diseases. Read more...

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Researchers Discover a Treatment to Block MS Progression

May 21, 2015 9:46 am | by University of Montreal | News | Comments

There is no effective cure for MS. Read more...

Chemo Before Surgery Benefits Patients with Advanced Ovarian Cancer

May 21, 2015 9:39 am | by Cancer Research UK | News | Comments

550 women with the disease took part in the trial, with 276 given the standard treatment of surgery followed by six cycles of chemotherapy, and 274 had surgery after three cycles of chemotherapy. Read more...

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Actavis Launches New Alzheimer's Disease Therapy

May 21, 2015 9:30 am | News | Comments

The drug was approved by the U.S. Food and Drug Administration (FDA) in December for the treatment of moderate to severe Alzheimer's disease in patients stabilized on memantine hydrochloride and donepezil hydrochloride. Read more...

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Brain Plaque Forecasts Alzheimer’s Years in Advance, Studies Confirm

May 20, 2015 1:49 pm | by Stephanie Guzowski, Editor | News | Comments

Brain plaques may appear up to 30 years prior to developing Alzheimer’s disease, according to the largest analysis to date of beta amyloid in people’s brains. Findings from two new meta-analyses  also confirm that amyloid screening, by PET scan or cerebral spinal fluid test, can help identify the best participants for clinical trials of Alzheimer’s drugs. Read more...

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Lakewood-Amedex: Novel Class Of Antimicrobials Kills Multidrug Resistant-Tuberculosis

May 20, 2015 12:51 pm | News | Comments

Lakewood-Amedex Inc., a leading developer of novel anti-infective pharmaceuticals, announced today that a recent series of in vitro studies conducted by Southern Research in Birmingham, Alabama, have demonstrated that its novel class of antimicrobials, named bisphosphocins, have proven effective at killing multidrug-resistant (MDR) strains.  Read more...

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