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DDD Update

Daily news and top headlines for drug research professionals

Early Lead Exposure Affects Gene Expression Throughout Life

July 13, 2015 11:53 am | by NC State University | News | Comments

A team of researchers led by North Carolina State University biologists Cathrine Hoyo and Randy Jirtle have found links between lead exposure in children and epigenetic alterations in regulatory regions of genes that are imprinted and known to be critical in growth regulation and brain development. Read more...

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Clinical Trial Shows Efficacy of New Psoriasis Medication

July 13, 2015 11:41 am | by Northwestern Medicine | News | Comments

A phase 2 clinical trial led by Northwestern Medicine investigators shows that a new psoriasis drug called guselkumab has greater efficacy than the current standard of care for the chronic skin condition. Read more...

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Scientists Win $1.2 Grant to Study Environmental Triggers of Lupus, RA

July 13, 2015 11:22 am | by The Scripps Research Institute | News | Comments

According to the U.S. Centers for Disease Control and Prevention, at least 1.5 million Americans suffer from rheumatoid arthritis and 322,000 have lupus, a chronic and potentially life-threatening disease that can damage skin, joints and organs. Read more...

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Pfizer Opens Chile-Based Precision Medicine Center

July 13, 2015 9:14 am | by Ryan Bushey, Associate Editor | Articles | Comments

Investigating lung cancer will be the center's first endeavor. Read more...

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Roche's Investigational Immunotherapy Shrank Bladder Cancer Tumors in Pivotal Study

July 13, 2015 8:45 am | News | Comments

Last year, the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for atezolizumab in people whose metastatic bladder cancer expressed PD-L1. Read more...

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Optical 'Dog's Nose' Developed to Detect Cancer, Other Diseases

July 13, 2015 8:39 am | by Bevin Fletcher, Associate Editor | News | Comments

Although there is much research needed in breath analysis, the team believes a working prototype could be ready in two to three years. Read more...

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Tests Show Ebola in Liberia Linked to Virus Months Ago

July 13, 2015 8:26 am | by Carley Petesch, Associated Press | News | Comments

More than 4,800 Liberians died of Ebola before the country was declared free of transmissions in May. Read more...

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Foreigner with MERS in Philippines Now Free of the Virus

July 13, 2015 8:26 am | by The Associated Press | News | Comments

Officials have not disclosed the nationality of the patient, who arrived in the Philippines on June 19 from Saudi Arabia but also stayed in Dubai. Read more...

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Novo Nordisk Successfully Completes First Phase 3a Trial for Semaglutide

July 13, 2015 8:25 am | News | Comments

The most common adverse events were related to the gastrointestinal system, primarily nausea, were comparable to Victoza in similar trials and diminished over time. Read more...

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Obesity Drug Has No Effect on Baby Birthweights, Study Finds

July 10, 2015 11:03 am | News | Comments

Treating obese pregnant women with a diabetes drug does not stop their babies from being born overweight, a study has found. Read more...

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Lilly Statement on FDA Advisory Committee Review of Necitumumab

July 10, 2015 10:56 am | News | Comments

The U.S. Food and Drug Administration's (FDA) Oncologic Drugs Advisory Committee (ODAC) met today to discuss the data supporting Eli Lilly and Company's (NYSE: LLY) necitumumab in combination with gemcitabine and cisplatin for use in first-line treatment of patients with advanced squamous non-small cell lung cancer (NSCLC). Read more...

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Neogen's ANSR for Listeria Monocytogenes Receives AOAC Approval

July 10, 2015 10:51 am | News | Comments

Neogen Corporation has received approval from the AOAC Research Institute for its new rapid and accurate test to definitively detect Listeria monocytogenes DNA in food and environmental samples. Read more...

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Researchers Link Liver Disease, Drug Metabolism

July 10, 2015 10:47 am | by University of Arizona, College of Pharmacy | News | Comments

Researchers at the University of Arizona College of Pharmacy have discovered that nonalcoholic steatohepatitis (NASH), an increasingly common but often undiagnosed liver disease, could have significant medical implications for people with type 2 diabetes. Read more...

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House Bill Would Speed Drug Approvals, Boost Research

July 10, 2015 10:41 am | by Alan Fram, Associated Press | News | Comments

Pressed by industry and patients' groups, the House neared approval Friday of a bipartisan bill that would speed federal approval of drugs and medical devices and boost biomedical research. Read more...

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Drug Discovery Spotlight: Novartis’ Heart Failure Drug Gets FDA-Approved; Small Birth-Defect Risk from Antidepressants

July 10, 2015 10:23 am | by Stephanie Guzowski, Editor | News | Comments

Novartis’s heart failure drug impressed this week, receiving FDA approval 6 weeks ahead of a scheduled deadline. Some SSRIs did not turn up any links to birth defects, while others, like Paxil and Prozac show limited associations. Read more...

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