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DDD Update

Daily news and top headlines for drug research professionals

FDA Clears Asterias to Begin Stem Cell Trial

August 27, 2014 3:08 pm | News | Comments

Asterias Biotherapeutics Inc. has received clearance from the FDA to initiate a Phase 1/2a clinical trial of its product, AST-OPC1, in patients with complete cervical spinal cord injury. Read more...               

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Marijuana Compound May Slow, Halt Alzheimer’s

August 27, 2014 3:00 pm | News | Comments

Extremely low levels of the compound in marijuana known as delta-9-tetrahydrocannabinol, or THC, may slow or halt the progression of Alzheimer’s disease, a new study says. Read more...                   

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Potential Therapy for Sudan Ebola Strain May Contain Future Outbreaks

August 27, 2014 2:45 pm | News | Comments

Ebola is a rare, but deadly disease that exists as five strains, none of which have approved therapies. One of the most lethal strains is the Sudan ebolavirus (SUDV). In a new study, researchers report a possible therapy that could someday help treat patients infected with SUDV. Read more...

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Amgen Heart Failure Drug Gets Priority Review

August 27, 2014 2:32 pm | News | Comments

Amgen announced the FDA has granted priority review designation for ivabradine for the treatment of chronic heart failure (HF). Ivabradine is an oral drug that inhibits the If current ("funny" current) in the sinoatrial node. Read more...   

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Compound Suppresses Binge Eating in Mice

August 27, 2014 2:26 pm | News | Comments

Researchers found that the hormone estrogen can specifically trigger brain serotonin neurons to inhibit binge eating, which affects about 5 to 10 percent of U.S. adults, in female mice. Read more...               

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Drug Promising as Potential Anemia Treatment

August 27, 2014 2:21 pm | News | Comments

An experimental drug designed to help regulate the blood’s iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment. Read more...         

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Merck Serono Breaks Ground on New China Facility

August 27, 2014 11:09 am | News | Comments

Merck Serono, the biopharmaceutical division of Merck, held the groundbreaking ceremony for its new pharmaceutical manufacturing facility in Nantong, China. Read more...                       

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EC Approves BMS Drug as Hep C Combo Treatment

August 27, 2014 11:03 am | News | Comments

Bristol-Myers Squibb Co. announced that the European Commission has approved Daklinza (daclatasvir) for use in combination with other medicinal products across genotypes 1, 2, 3 and 4 for the treatment of chronic hepatitis C virus infection in adults. Read more...

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Targeted Neuroblastoma Therapy One Step Closer

August 27, 2014 10:52 am | News | Comments

Researchers have uncovered new targets for therapy in the childhood cancer neuroblastoma, bringing hope for the development of novel treatments. Read more...                           

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3rd Doctor Dies from Ebola in Sierra Leone

August 27, 2014 10:27 am | by Clarence Roy-Macaulay | News | Comments

A third top doctor has died from Ebola in Sierra Leone, a government official said Wednesday, as health workers tried to determine how a fourth scientist also contracted the disease before being evacuated to Europe. Read more...       

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Japan Lab Unable to Replicate Stem Cell Results

August 27, 2014 10:22 am | by Elaine Kurtenbach, AP Business Writer | News | Comments

The Japanese laboratory that retracted a paper reporting a potentially major breakthrough in stem cell research said Wednesday its researchers have not managed to replicate the results. Read more...               

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A ‘Second Revolution’ in Drug Discovery and Development

August 27, 2014 9:58 am | by Seth Lederman, M.D., CEO, Tonix Pharmaceuticals | Articles | Comments

Drugs can be discovered and developed in two very different ways: at an evolutionary pace and at a revolutionary pace. The “first revolution” in biological psychiatry took place in the 1950s, and now, in the 21st century, a “second revolution” of drug development and discovery is taking place, driven by repurposing. Read more...

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New Statin Guidelines are an Improvement, Study Shows

August 26, 2014 3:18 pm | News | Comments

New national guidelines can improve the way statin drugs are prescribed to patients at risk for cardiovascular disease, a study has found. Read more...                             

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FDA Approves Additional Promacta Indication

August 26, 2014 3:14 pm | News | Comments

GSK announced that the FDA has approved a supplemental New Drug Application for the once-daily use of Promacta (eltrombopag) in patients with severe aplastic anemia (SAA) who have had an insufficient response to immunosuppressive therapy (IST). Read more...

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Alkermes Launches Phase 1 Pain Treatment Study

August 26, 2014 3:08 pm | News | Comments

Alkermes plc announced the initiation of a Phase 1 clinical study of ALKS 7106, a proprietary, novel, oral, small-molecule drug candidate for the treatment of pain. Read more...                       

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