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DDD Update

Daily news and top headlines for drug research professionals

PhRMA, Epilepsy Foundation Report More Than 400 Neurological Disorder Medicines in Development

July 14, 2015 12:03 pm | News | Comments

America's biopharmaceutical research companies are currently developing 420 medicines for patients suffering from neurological disorders, including epilepsy, Alzheimer's disease, multiple sclerosis (MS) and Parkinson's disease. Read more...

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ANI Acquires 22 Generic Drug Products from Teva for $25 million

July 14, 2015 11:55 am | News | Comments

ANI Pharmaceuticals, Inc. ("ANI") today announced that it has acquired 22 previously marketed generic drug products from Teva Pharmaceuticals for $25 million in cash and a percentage of future gross profits from product sales. Read more...

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Study: Silent Cancer in Moms A Rare Result in Prenatal Tests

July 14, 2015 11:35 am | by By Lindsey Tanner, AP Medical Writer | News | Comments

For pregnant women, abnormal results from certain prenatal tests may signal that something is wrong - with the moms-to-be, not the fetus, a preliminary study suggests. Read more...

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Hepatitis C Medications Found Cost-Effective by Panel

July 14, 2015 11:03 am | by Stephanie Guzowski, Editor | News | Comments

A panel comprised of physicians, health care workers and scientists have recommended that hepatitis C treatments with list prices of $1,000 per daily dose are cost-effective, according to a draft of their report obtained by Bloomberg Business. Read more...

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Mylan One of First to Launch Generic Version of Namenda Tablets

July 14, 2015 9:02 am | News | Comments

Mylan received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for this product, which is indicated for the treatment of moderate to severe dementia of the Alzheimer's type. Read more...

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Soliris Could Drive Myasthenia Gravis Treatment Market Value Beyond $550M by 2024

July 14, 2015 8:55 am | by Melina Reisenberg, Ph.d., Neurology Analyst, GlobalData | Articles | Comments

Soliris is expected to launch in the US in 2018, followed by its entry in the five European countries (5EU) and Japan in 2019 and 2020, respectively. Read more...

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Oxford Osteoarthritis Patients in New Clinical Trial

July 14, 2015 8:44 am | by University of Oxford | News | Comments

The trial will establish if a drug called methotrexate, commonly taken by people with rheumatoid arthritis, can also be effective in treating osteoarthritis: a completely different condition. Read more...

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New Drug Combo Could Make Cancer More Sensitive to Chemo

July 14, 2015 8:43 am | by Cancer Research UK | News | Comments

These drugs are commonly used to treat several cancers – including breast, ovarian and prostate cancers. But not all cancers respond to them, and it’s difficult to predict which patients will benefit. Read more...

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EU Drug Regulator Starts Safety Review of HPV Vaccines

July 14, 2015 8:41 am | by The Associated Press | News | Comments

Current HPV vaccine information doesn't include warnings about these conditions and no causal link has been found. Read more...

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Streamlining Biologic Purification and Screening Workflow with Multi-D Chromatography

July 14, 2015 8:41 am | by Philip Chapman, Global Product Manager; Phillip Elms, Senior Scientist; Gunjan Choudhary, Technical Editor, of Bio-Rad Laboratories | Articles | Comments

Chromatography plays an important role in the screening of insoluble aggregates during biologics production. However, the need for multiple purification steps makes traditional workflows time -consuming and labor-intensive. Multidimensional chromatography overcomes these limitations through automation of the purification and screening workflows. Read more...

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Gilead's Harvoni Overtakes Sovaldi in Hepatitis C Market

July 13, 2015 1:07 pm | by Ryan Bushey, Associate Editor | Articles | Comments

Although these drugs have yielded billions of dollars in sales for Gilead, the drugmaker still has to face a few challenges domestically and abroad. Read more...

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Bringing Speed to Study Startup

July 13, 2015 12:20 pm | by Jae Chung, founder and president of goBalto. | Articles | Comments

There is intense pressure to speed clinical trials and restrain costs, but inefficiencies tied to complicated protocols, globalization, and paper-based methods have stalled these efforts. The current status of clinical trials has encouraged stakeholders to embrace cloud-based solutions such as clinical trial management systems (CTMS). Read more...

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Troubleshooting CRISPR

July 13, 2015 12:03 pm | by Harvard University | News | Comments

Researchers develop predictive software for more precise genome editing. Read more...

Early Lead Exposure Affects Gene Expression Throughout Life

July 13, 2015 11:53 am | by NC State University | News | Comments

A team of researchers led by North Carolina State University biologists Cathrine Hoyo and Randy Jirtle have found links between lead exposure in children and epigenetic alterations in regulatory regions of genes that are imprinted and known to be critical in growth regulation and brain development. Read more...

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Clinical Trial Shows Efficacy of New Psoriasis Medication

July 13, 2015 11:41 am | by Northwestern Medicine | News | Comments

A phase 2 clinical trial led by Northwestern Medicine investigators shows that a new psoriasis drug called guselkumab has greater efficacy than the current standard of care for the chronic skin condition. Read more...

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