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DDD Update

Daily news and top headlines for drug research professionals

Thousands Protest in Spain for Better Hepatitis C Treatment

January 12, 2015 9:34 am | by Associated Press | News | Comments

Thousands of people affected by hepatitis C have marched in several Spanish cities to press for easier access to latest-generation medicines for the deadly liver disease. Read more...                            

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Shire to Buy Specialty Drugmaker NPS Pharma For $5.2B

January 12, 2015 9:27 am | by Associated Press | News | Comments

Irish drugmaker Shire PLC said it will pay $5.2 billion to acquire NPS Pharmaceuticals Inc., which specializes in drugs for rare conditions. Read more...;                                                                 

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Adopting Adaptive Designs: Update

January 12, 2015 8:59 am | by Phil Birch, DPhil, VP Innovation Strategy, Alliance Partnerships at ICON plc. | Articles | Comments

In early 2013, adaptive clinical trials represented 20% of all clinical trials, according to the Tufts CSDD seminal report, The Adoption and Impact of Adaptive Trial DesignsThough that number was expected to grow, lack of education and industry conservatism were named as some of the greatest barriers to widespread adoption of adaptive designs. Read more...

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Study Links Enzyme to Alzheimer's Disease

January 9, 2015 11:57 am | by Rockefeller University | News | Comments

Unclogging the body's protein disposal system may improve memory in patients with Alzheimer's disease (AD), according to a study from scientists at Kyungpook National University in Korea published in The Journal of Experimental Medicine. Read more...

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Regeneron, Sanofi: Positive Results in Hypercholesterolemia Trials

January 9, 2015 11:28 am | by Sanofi | News | Comments

Regeneron Pharmaceuticals, Inc. and Sanofi announced that two new ODYSSEY trials, which are the first Phase 3 trials to assess alirocumab administered every four weeks, met their primary efficacy endpoints. Read more...               

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FDA Approves Impax Pharmaceutical's Parkinson's Treatment

January 9, 2015 11:21 am | by Impax Pharmaceuticals | News | Comments

Impax Pharmaceuticals, a division of Impax Laboratories, Inc. announced that the U.S. Food and Drug Administration (FDA) approved RYTARY, an extended-release oral capsule formulation of carbidopa-levodopa, for the treatment of Parkinson's disease, post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication and / or manganese intoxication. Read more...

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Scientists Illuminate Molecular Mechanism Powering Cells

January 9, 2015 10:53 am | by Scripps Institute | News | Comments

A team led by structural biologists at The Scripps Research Institute (TSRI) has taken a big step toward understanding the intricate molecular mechanism of a metabolic enzyme produced in most forms of life on Earth. Read more...               

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WHO Approves Meningitis A Vaccine for Infants

January 9, 2015 10:43 am | by Meningitis Vaccine Project | News | Comments

The World Health Organization (WHO) has opened the door to routine immunization of infants in sub-Saharan Africa by approving for use an innovative and affordable vaccine that has all but rid the meningitis belt of a major cause of deadly epidemics. Read more...

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World-First Stem Cell Clinical Trials in 2014

January 9, 2015 10:02 am | by Drug Discovery & Development Staff | Articles | Comments

The year 2014 saw many world-firsts in the stem cell field, from the creation of human eggs and sperm from adult cells as reported in Cell, to the discovery reported in Science that a single protein (GDF11) in young blood can reverse aging processes in both stem, and terminally differentiated, cells of brain and muscle. Read more...

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Daiichi Sankyo's AFib Tablets Gain FDA Approval

January 9, 2015 9:36 am | News | Comments

The tablets reduce the risk of stroke and systemic embolism. Read more...                               

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Bacteria May Contribute to Wound-Induced Skin Cancer

January 9, 2015 9:24 am | by King's College London | News | Comments

Researchers have identified a new mechanism by which skin damage triggers the formation of tumors. Read more...                         

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FDA Approves Roche's HIV, Hepatitis Screening Test

January 9, 2015 9:09 am | News | Comments

The combination of viral target detection and identification steps on a fully automated system offers workflow advantages to blood and plasma testing centers. Read more...               

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Cipher Pharmaceuticals Acquires Melanovus Oncology Assets

January 9, 2015 9:02 am | News | Comments

The transaction includes an upfront payment to Melanovus of 500,000, as well as the payment of certain IP expenses related to patent prosecution and maintenance. Read more...             

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New Bioanalytical Technology Holds Promise for Alzheimer’s Research

January 9, 2015 9:00 am | by Stephen Turner, CEO, Protea Biosciences Group Inc.; Roxana Carare, MD, PhD., University of Southampton, and Peggi M. Angel, PhD., Senior Scientist, LAESI Mass Spectrometry Imaging, Protea Biosciences Group Inc. | Articles | Comments

Alzheimer's disease (AD) is a progressive, neurodegenerative disorder that is the leading cause of dementia in the elderly (60%), affecting 13% to 20% of people over the age of 65 years. Read more...                                 

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2 Leading Ebola Vaccines Appear Safe, Further Tests Starting

January 9, 2015 8:51 am | by Maria Cheng - AP Medical Writer | News | Comments

The World Health Organization said the two leading Ebola vaccines appear safe and will soon be tested in healthy volunteers in West Africa. Read more...                  

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