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Strategies & Technologies Driving Drug Discovery to Market
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More Evidence HIV/AIDS Fight Requires Multiple Approaches

January 25, 2016 10:23 am | by Andrew M. Seaman, Reuters | News | Comments

A currently available pill could significantly curb new HIV infections among gay and bisexual men in the UK, if prevention and treatment programs are also expanded, researchers say. Read more...

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OncoMed Shares Fall After Discouraging News on Pancreatic Cancer Drug

January 25, 2016 10:02 am | by Ben Fidler, Xconomy | News | Comments

OncoMed Pharmaceuticals has been adept at bringing in partners like GlaxoSmithKline and Celgene to help fund its cancer stem cell work. But the Redwood City, CA, company took a big hit this morning, as word emerged that one of its most advanced drugs—a potential cancer treatment that’s part of an alliance with GlaxoSmithKline—isn’t performing as hoped in a test against pancreatic cancer. Read more...

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Former NJ Hospital Pharmacist Accused of Morphine Theft

January 25, 2016 9:48 am | by Associated Press | News | Comments

Prosecutors say a former registered pharmacist is accused of stealing morphine and replacing it with saline at a southern New Jersey hospital where he once worked. Read more...

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Unifying In Silico and Physical Experimentation to Radically Accelerate Innovation

January 25, 2016 9:27 am | by Adrian Stevens and Tim Moran, of Dassault Systèmes BIOVIA | Articles | Comments

Predictive data models and information about previous experiments can help scientists recognize which choices are likely to accelerate progress and which will lead to dead ends. The goal is to achieve better insights sooner by making data available throughout the entire workflow. Read more...

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A Defense Protein that Causes Cancer

January 25, 2016 8:57 am | by University of Geneva | News | Comments

Cancer is caused by the growth of an abnormal cell which harbors DNA mutations. Read more...

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Easier Diagnosis for Fungal Infection of the Lungs

January 25, 2016 8:51 am | by University of Exeter | News | Comments

A new clinical imaging method developed in collaboration with a University of Exeter academic may enable doctors to tackle one of the main killers of patients with weakened immune systems sooner and more effectively. Read more...

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EC Confirms CMDh Recommendation

January 25, 2016 8:45 am | News | Comments

EC has taken an EU-wide legally binding decision and confirmed the favorable benefit/risk profile of ambroxol and bromhexine containing medicines. Read more...

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Better Healthcare Could Lower Crippling Personal Costs of TB Care in China

January 25, 2016 8:41 am | by Biomed Central | News | Comments

Improved universal healthcare is urgently needed to lower catastrophic health expenditure (CHE) for low-income tuberculosis (TB) patients in China. Read more...

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GSK, Astra, J&J, Link with Universities in New Drug Research Fund

January 25, 2016 8:36 am | by Ben Hirschler, Reuters | News | Comments

GlaxoSmithKline, AstraZeneca and Johnson & Johnson have joined with three leading British universities to create a new fund backing early drug research. Read more...

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Health Officials Probe Tie Between Zika, Paralyzing Syndrome

January 25, 2016 8:32 am | by Jenny Barchfield and Marcos Aleman, Associated Press | News | Comments

Two Latin American countries are investigating whether outbreaks of the mosquito-borne Zika virus are behind a rise in a rare and sometimes life-threatening nerve condition that can cause paralysis and leave victims on life-support. Read more...

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New Data Shows SGLT2 Inhibitors May Be Effective in Preventing Kidney Failure

January 22, 2016 12:26 pm | by Vlado Perkovic MBBS, PhD, FRACP, FASN, Executive Director, The George Institute | News | Comments

New data presented at the American Society of Nephrology meeting in San Diego last November offers new hope to people with diabetes at risk of kidney disease and kidney failure. They suggest a new class of glucose-lowering agents, sodium glucose co-transporter type 2 (SGLT2) inhibitors, may be effective in preventing kidney failure. Read more...

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FDA Approves New Kyprolis Combination Therapy for Refractory Multiple Myeloma

January 22, 2016 11:16 am | News | Comments

Amgen today announced that the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) of Kyprolis(carfilzomib) for Injection in combination with dexamethasone or with lenalidomide plus dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma who have received one to three lines of therapy. Read more...

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Antibodies May Provide 'Silver Bullet' for Ebola Viruses

January 22, 2016 11:08 am | by Vanderbilt University Medical Center | News | Comments

There may be a "silver bullet" for Ebola, a family of hemorrhagic viruses, one of which has killed more than 11,000 people in West Africa in the past two years. Researchers at Vanderbilt University Medical Center and the University of Texas Medical Branch in Galveston reported today that they have isolated human monoclonal antibodies from Ebola survivors which can neutralize multiple species of the virus. Read more...

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Mitochondrial Troublemakers Unmasked in Lupus

January 22, 2016 11:03 am | by University of Washington | News | Comments

New findings expose how mitochondria might instigate lupus-like inflammation. Read more...

For Adults with Common Form of Leukemia, New Drug Promises Fewer Side Effects

January 22, 2016 10:57 am | by Columbia University | News | Comments

In phase 1/2 trial, new targeted therapy for hard-to-treat chronic lymphocytic leukemia appears as effective as ibrutinib with fewer side effects. Read more...

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