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DDD Update

Daily news and top headlines for drug research professionals

Amgen Heart Failure Drug Gets Priority Review

August 27, 2014 2:32 pm | News | Comments

Amgen announced the FDA has granted priority review designation for ivabradine for the treatment of chronic heart failure (HF). Ivabradine is an oral drug that inhibits the If current ("funny" current) in the sinoatrial node. Read more...   

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Compound Suppresses Binge Eating in Mice

August 27, 2014 2:26 pm | News | Comments

Researchers found that the hormone estrogen can specifically trigger brain serotonin neurons to inhibit binge eating, which affects about 5 to 10 percent of U.S. adults, in female mice. Read more...               

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Drug Promising as Potential Anemia Treatment

August 27, 2014 2:21 pm | News | Comments

An experimental drug designed to help regulate the blood’s iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment. Read more...         

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Merck Serono Breaks Ground on New China Facility

August 27, 2014 11:09 am | News | Comments

Merck Serono, the biopharmaceutical division of Merck, held the groundbreaking ceremony for its new pharmaceutical manufacturing facility in Nantong, China. Read more...                       

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EC Approves BMS Drug as Hep C Combo Treatment

August 27, 2014 11:03 am | News | Comments

Bristol-Myers Squibb Co. announced that the European Commission has approved Daklinza (daclatasvir) for use in combination with other medicinal products across genotypes 1, 2, 3 and 4 for the treatment of chronic hepatitis C virus infection in adults. Read more...

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Targeted Neuroblastoma Therapy One Step Closer

August 27, 2014 10:52 am | News | Comments

Researchers have uncovered new targets for therapy in the childhood cancer neuroblastoma, bringing hope for the development of novel treatments. Read more...                           

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3rd Doctor Dies from Ebola in Sierra Leone

August 27, 2014 10:27 am | by Clarence Roy-Macaulay | News | Comments

A third top doctor has died from Ebola in Sierra Leone, a government official said Wednesday, as health workers tried to determine how a fourth scientist also contracted the disease before being evacuated to Europe. Read more...       

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Japan Lab Unable to Replicate Stem Cell Results

August 27, 2014 10:22 am | by Elaine Kurtenbach, AP Business Writer | News | Comments

The Japanese laboratory that retracted a paper reporting a potentially major breakthrough in stem cell research said Wednesday its researchers have not managed to replicate the results. Read more...               

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A ‘Second Revolution’ in Drug Discovery and Development

August 27, 2014 9:58 am | by Seth Lederman, M.D., CEO, Tonix Pharmaceuticals | Articles | Comments

Drugs can be discovered and developed in two very different ways: at an evolutionary pace and at a revolutionary pace. The “first revolution” in biological psychiatry took place in the 1950s, and now, in the 21st century, a “second revolution” of drug development and discovery is taking place, driven by repurposing. Read more...

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New Statin Guidelines are an Improvement, Study Shows

August 26, 2014 3:18 pm | News | Comments

New national guidelines can improve the way statin drugs are prescribed to patients at risk for cardiovascular disease, a study has found. Read more...                             

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FDA Approves Additional Promacta Indication

August 26, 2014 3:14 pm | News | Comments

GSK announced that the FDA has approved a supplemental New Drug Application for the once-daily use of Promacta (eltrombopag) in patients with severe aplastic anemia (SAA) who have had an insufficient response to immunosuppressive therapy (IST). Read more...

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Alkermes Launches Phase 1 Pain Treatment Study

August 26, 2014 3:08 pm | News | Comments

Alkermes plc announced the initiation of a Phase 1 clinical study of ALKS 7106, a proprietary, novel, oral, small-molecule drug candidate for the treatment of pain. Read more...                       

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Kite Pharma's Lymphoma Drug Excels in Trial

August 26, 2014 3:03 pm | News | Comments

Shares of Kite Pharma surged before markets opened Tuesday after the drug developer detailed promising results for its most advanced product, a potential treatment for an aggressive form of non-Hodgkin's lymphoma. Read more...       

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Pfizer, Merck to Explore Novel Anti-Cancer Combo

August 26, 2014 2:55 pm | News | Comments

Pfizer Inc. and Merck & Co. Inc. announced that they have entered into an agreement to explore the therapeutic potential of the combination of Pfizer’s crizotinib with Merck’s investigational anti-PD-1 antibody pembrolizumab. Read more...   

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Cancer-Fighting Drugs Might Also Stop Malaria Early

August 26, 2014 2:47 pm | News | Comments

Scientists searching for new drugs to fight malaria have identified a number of compounds- some of which are currently in clinical trials to treat cancer- that could add to the anti-malarial arsenal. Read more...            

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