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DDD Update

Daily news and top headlines for drug research professionals

Nasal Spray Vaccine Could Protect Against Ebola Virus

November 3, 2014 12:44 pm | News | Comments

A nasal vaccine in development by researchers at The University of Texas at Austin has been shown to provide long-term protection for non-human primates against the deadly Ebola virus. Read more...

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Researcher Debunks Alzheimer's Development Theory

November 3, 2014 12:36 pm | News | Comments

New research points to tau, not amyloid-beta (Abeta) plaque, as the seminal event that spurs neuron death in disorders such as Alzheimer's disease. The finding, which dramatically alters the prevailing theory of Alzheimer's development, also explains why some people with plaque build-up in their brains don't have dementia. Read more...

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Inventiva Gains Positive Opinion for Orphan Drug Designation

November 3, 2014 11:20 am | News | Comments

Inventiva has received a positive opinion for a new orphan drug designation for systemic sclerosis. Read more...                         

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Pharming, Salix Launch HAE Treatment

November 3, 2014 11:16 am | News | Comments

Pharming Group NV and Salix Pharmaceuticals, Ltd. announced the launch of Ruconest (C1 Esterase Inhibitor [Recombinant]) 50 IU/kg in the United States for the treatment of acute angioedema attacks in adult and adolescent patients with hereditary angioedema (HAE). Read more...

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Regulatory Data: Vital for DDI Risk-Mitigation Efforts

November 3, 2014 11:04 am | by Philip MacLaughlin, Product Director, PharmaPendium, Elsevier | Articles | Comments

Unanticipated adverse drug-drug interactions (DDIs) have led to the withdrawal of several high-profile drugs that had been available for a number of years, including terfenadine, astemizole, cisapride, grepafloxacin and mibefradil.  Read more... 

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BMS Signs Exclusive Option for New Pulmonary Fibrosis Inhibitor

November 3, 2014 10:52 am | News | Comments

Bristol-Meyers Squibb and Galecto Biotech AB announced that the companies have entered into an agreement that provides BMS the exclusive option to acquire a a novel inhaled inhibitor for the treatment of idiopathic pulmonary fibrosis. Read more...  

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Gates Foundation Boosts Aid to Stamp Out Malaria

November 3, 2014 9:11 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Philanthropist Bill Gates says he wants to end malaria in his lifetime and will give more money toward that goal. Read more...                       

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The Man with a Thousand Brains

November 3, 2014 8:56 am | News | Comments

Forty million people worldwide are living with Alzheimer’s and this is only set to increase. But tiny brains grown in culture could help scientists learn more about this mysterious disease – and test new drugs. Read more...                          

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First Human Clinical Trial of 'C dots' Highlights Safety

October 31, 2014 2:14 pm | News | Comments

A first clinical trial of these ultrasmall, multifunctional particles has deemed them safe for humans and cleared easily by the body. Read more...                   

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Synthetic Lethality Offers New Approach to Kill Tumor Cells

October 31, 2014 1:51 pm | News | Comments

A recent approach to treat cancer called synthetic lethality takes advantage of genetic alterations in cancer cells that make them more susceptible to certain drugs. Read more...              

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Mouse Model Could Accelerate Ebola Treatment Research

October 31, 2014 1:36 pm | News | Comments

Researchers at the University of North Carolina at Chapel Hill and colleagues have developed the first genetic strain of mice that can be infected with Ebola and display symptoms similar to those that humans experience. Read more...     

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Scientists Capture Picture of microRNA in Action

October 31, 2014 1:16 pm | News | Comments

The findings add greatly to the understanding of a fundamental system of regulation in biology, and should accelerate the development of therapies that harness its power. Read more...             

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Game Changing Migraine Med to be Available November 2014

October 31, 2014 12:54 pm | News | Comments

Migranade Inc announced the new migraine medication will be available to the 36 million U.S. migraine sufferers November 2014. Read more...                    

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Soldier or Civilian, Ebola Protocols Are Not The Same

October 31, 2014 12:36 pm | by Jim Kuhnhenn and Robert Burns - Associated Press | News | Comments

Ebola protocols are drastically different for soldiers and civilians. Read more...                              

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Special Report: Many Stem Cell Clinical Trials for Macular Degeneration

October 31, 2014 11:22 am | by Cynthia Fox, Science Editor | Articles | Comments

The most potent stem cells are coming to patients after helping blind (and nearly blind) mice see for years. Read more...                                                                                

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