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DDD Update

Daily news and top headlines for drug research professionals

Scientists Use Cancer Drug in Gene Therapy

June 27, 2014 1:28 pm | News | Comments

Scientists working to make gene therapy a reality have solved a major hurdle - how to bypass a blood stem cell’s natural defenses and efficiently insert disease-fighting genes into the cell’s genome - with rapamycin, which is commonly used to slow cancer growth and prevent organ rejection. Read more...

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EU Panel OKs Expanded Use of Roche Cancer Drug

June 27, 2014 11:10 am | News | Comments

Roche announced that the EU Committee for Medicinal Products for Human Use recommended that the European Commission approve the use of Avastin in combination with chemotherapy as a treatment for women with ovarian cancer that is resistant to platinum-containing chemotherapy. Read more...

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Gilead Submits Sofosbuvir NDA in Japan

June 27, 2014 11:01 am | News | Comments

Gilead announced that the company has submitted a New Drug Application to Japan’s Pharmaceutical and Medical Devices Agency for approval of sofosbuvir for the treatment of chronic hepatitis C virus (HCV) infection. Read more...       

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CHMP Recommends Bayer Drug for Gastrointestinal Stromal Tumors

June 27, 2014 10:54 am | News | Comments

The oncology compound regorafenib (Stivarga) from Bayer has been recommended for approval by the European Committee for Medicinal Products for Human Use for the treatment of adult patients with unresectable or metastatic gastrointestinal stromal tumors. Read more...

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Lilly-BI Compound is First Biosimilar Insulin Backed by CHMP

June 27, 2014 10:41 am | News | Comments

The investigational compound LY2963016, a new insulin glargine product from Eli Lilly and Co. and Boehringer Ingelheim for the treatment of type 1 and type 2 diabetes, is the first biosimilar insulin recommended for approval in the EU. Read more...

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Prosensa Snags $200,000 Research Grant from PPMD

June 27, 2014 10:26 am | News | Comments

Prosensa announced that the company's vice president of drug discovery, Dr. Judith van Deutekom, has been awarded a $200,000 research grant from Parent Project Muscular Dystrophy to fund the development of a multi exon-skipping strategy for exons 10-30 of the dystrophin gene. Read more...

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Some Aggressive Cancers May Respond to Anti-Inflammatory Drugs

June 26, 2014 7:25 pm | News | Comments

New research raises the prospect that some cancer patients with aggressive tumors may benefit from a class of anti-inflammatory drugs used to treat rheumatoid arthritis. Read more...                   

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BI’s Pradaxa Antidote Gets FDA Breakthrough Status

June 26, 2014 2:12 pm | News | Comments

Boehringer Ingelheim Pharmaceuticals Inc. announced that the FDA has granted Breakthrough Therapy Designation to idarucizumab, an investigational fully humanized antibody fragment, or Fab, being studied as a specific antidote for Pradaxa. Read more...

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AbbVie Initiates New Veliparib Trial in Advanced Breast Cancer

June 26, 2014 2:01 pm | News | Comments

AbbVie announced the initiation of a Phase 3 clinical trial of its investigational compound, veliparib, when added to carboplatin and paclitaxel, two chemotherapeutic medicines, in patients with advanced breast cancer. Read more...      

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Low-dose Aspirin Use May Lower Pancreatic Cancer Risk

June 26, 2014 1:17 pm | News | Comments

The longer a person took low-dose aspirin, the lower his or her risk for developing pancreatic cancer, according to a new study. Men and women who took low-dose aspirin regularly had 48 percent reduction in their risk for developing pancreatic cancer. Read more...

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FDA Warns of Allergic Reactions With Acne Products

June 26, 2014 1:05 pm | by Matthew Perrone, AP Health Writer | News | Comments

Federal health officials are warning consumers who use popular anti-acne treatments about rare but potentially deadly allergic reactions that can cause swelling of the face and difficulty breathing. Read more...            

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Flu Spray Better Than Shots for Young Kids

June 26, 2014 12:57 pm | by Mike Stobbe, AP Medical Writer | News | Comments

When it comes to flu vaccines, a federal panel says a squirt in the nose is better than a shot in the arm for young children. The advisory panel voted Wednesday to advise doctors that FluMist nasal spray is a bit better at preventing flu in healthy young kids. Read more...

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Human Longevity Supports Innovation to Advance Treatment of Cancer, Other Diseases

June 26, 2014 11:10 am | News | Comments

Human Longevity Inc., a genomics and cell therapy-based diagnostic and therapeutic company focused on extending the healthy, high performance human life span, called on physicians, the insurance industry and political leaders to support promising new avenues of medical discovery on behalf of patients with life-threatening diseases including cancer. Read more...

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MicroRNA Offers Target for Osteoporosis and Bone Metastases Drugs

June 26, 2014 11:04 am | News | Comments

UT Southwestern cancer researchers have identified a promising molecule - miR-34a from a family of small molecules called microRNAs - that blocks bone destruction and, therefore, could provide a potential therapeutic target for osteoporosis and bone metastases of cancer. Read  more...

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G20 World Brain Mapping and Therapeutics Initiative Partners with EU Human Brain Project

June 26, 2014 10:57 am | News | Comments

According to the World Health Organization's large-scale studies, about a third of the adult worldwide population suffer from a mental disorder such as depression, anxiety and schizophrenia, and European Union, China, India, Japan and Australia are not immune from the high cost of healthcare despite having 100% government insurance. Read more...

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