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Daily news and top headlines for drug research professionals

Drug Discovery Spotlight: 'DocuSerial' on J&J; Antidepressant Paxil is Unsafe; Freezing Brains

September 18, 2015 10:11 am | by Stephanie Guzowski, Editor | News | Comments

Welcome to Drug Discovery Spotlight, where we’ve rounded up this week’s trending news stories.


DNA Methylation Test Might Predict Breast Cancer Relapse

September 17, 2015 4:48 pm | by Translational Genomics Research Institute | News | Comments

Every woman successfully treated for breast cancer lives with the knowledge that it could come back. New research published today in the journal Clinical Epigenetics may lead to a simple blood test to determine the risk of such recurrence, or the cancer invading other organs such as the lungs, bone or brain. Read more..


New Approach Found to Tackle Breast Cancer Hormone Therapy Resistance

September 17, 2015 4:39 pm | by University of Manchester | News | Comments

University of Manchester researchers funded by Breast Cancer Now have discovered a new explanation as to why women with oestrogen receptor positive (ER+) breast cancer develop resistance to hormone treatment, and a potential new approach to overcome the problem. Read more...


Global Consortium Rewrites the 'Cartography' of Dengue Virus

September 17, 2015 4:31 pm | by Cambridge University | News | Comments

An international consortium of laboratories worldwide that are studying the differences among dengue viruses has shown that while the long-held view that there are four genetically-distinct types of the virus holds, far more important are the differences in their antigenic properties. Read more...


Lipid Therapeutics Licenses Rights to UC Therapy to Nestlé Health Science

September 17, 2015 4:24 pm | News | Comments

Lipid Therapeutics today announces that it has entered into a licensing agreement with Nestlé Health Science for exclusive rights to Lipid Therapeutics' LT-02 compound (phosphatidylcholine), a novel barrier function therapy for patients with mild-to-moderate ulcerative colitis (UC), worldwide excluding Europe and Australia.  Read more..


Intarcia: Results From Two Successful Phase 3 Trials For Investigational Therapy In Type 2 Diabetes

September 17, 2015 4:20 pm | News | Comments

Intarcia Therapeutics, Inc. today announced the presentation of results from its first two Phase 3 clinical trials (FREEDOM-1 and FREEDOM-1 HBL) of its late-stage investigational candidate ITCA 650 (exenatide delivered continuously via a matchstick-size subcutaneous osmotic mini-pump) at the 51st European Association for the Study of Diabetes (EASD) Meeting in Stockholm, Sweden. Read more...


FDA Approves Allergan's Schizophrenia & Bipolar Disorder Treatment

September 17, 2015 4:11 pm | News | Comments

Allergan plc and Gedeon Richter Plc. announced today that the U.S. Food and Drug Administration (FDA) has approved Vraylar (cariprazine) capsules, an atypical antipsychotic, for the acute treatment of manic or mixed episodes associated with bipolar I disorder and for treatment of schizophrenia in adults. Read more...


Study: Type 2 Diabetes Pill Jardiance Cuts Risk of Death

September 17, 2015 1:28 pm | by Linda A. Johnson, AP Business Writer | News | Comments

Jardiance sharply reduced chances of dying in diabetic patients at high risk of heart complications, a study shows, making the medication the first shown to lengthen diabetics' lives. Read more...


Time for Flu Vaccine, Updated After Misery of Last Winter

September 17, 2015 1:23 pm | by Lauren Neergaard, AP Medical Writer | News | Comments

It's time for flu shots again, and health officials expect to avoid a repeat of the misery last winter, when immunizations weren't a good match for a nasty surprise strain. Read more...


Man Claims Bias Over Use of HIV-Blocking Drug

September 17, 2015 1:19 pm | by Denise Lavoie, AP Legal Affairs Writer | News | Comments

As a gay man, the Boston attorney thought he was doing the responsible thing when he asked his doctor to prescribe Truvada, a drug hailed as a way to halt the spread of AIDS. But when he tried to get long-term care insurance, Mutual of Omaha turned him down, saying it does not offer coverage to anyone who takes the drug. Read more...


Alzheimer’s Disease is Really Three Distinct Subtypes, UCLA Study Says

September 17, 2015 1:07 pm | by Seth Augenstein, Digital Reporter | News | Comments

Alzheimer’s Disease appears in three distinct subtypes, according to a study published this week. The discovery could fundamentally change the way that the disease is understood, treated – and eventually cured, said the University of California at Los Angeles scientist behind it. Read more...


Antidepressant Paxil Is Unsafe, Ineffective for Teens, Reanalysis Finds

September 17, 2015 12:21 pm | by Stephanie Guzowski, Editor | News | Comments

The widely prescribed antidepressant paroxetine — branded as Paxil, Aropax and Seroxat — isn’t a safe or effective treatment for depression in teens, finds a reanalysis of a 2001 study published Wednesday in The BMJ. Read more...


Clinical Need for Diabetic Kidney Disease Treatment Options

September 17, 2015 9:29 am | by James F. List, M.D., Ph.D., Global Therapeutic Area Head of Cardiovascular & Metabolism (CVM) at Janssen Research & Development | Articles | Comments

The skyrocketing global incidence of type 2 diabetes mellitus (T2DM) has created a clinical need and developmental opportunity to better address the growing impact of diabetic kidney disease, or kidney damage caused by diabetes, on the patient community and health care system. Read more...


BPH Treatment Market Value to Reach Nearly $5B by 2024

September 17, 2015 8:15 am | by Valentina Gburcik, Ph.D., GlobalData’s Director of Cardiovascular & Metabolic Disorders | News | Comments

Three novel therapies will contribute to the growth of the BPH therapeutics market. Read more...


ECC 2015: Eisai to Present New Clinical Data on Lenvima, Halaven

September 17, 2015 8:10 am | News | Comments

Eisai positions oncology as a key franchise area.



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