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Daily news and top headlines for drug research professionals

Researchers Discover More Than 3,000 Genes in a Little-studied Part of the Human Genome

October 27, 2015 11:15 am | by UCLA | News | Comments

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered more than 3,000 previously unknown genes in a poorly understood part of the genome. These genes, found in rare cells in bone marrow and in the thymus, give scientists a new understanding of how the human immune system develops. Read more...


Intestine-Specific Delivery of Insulin Demonstrates Promise with New Oral Formulation

October 27, 2015 10:50 am | by American Association of Pharmaceutical Scientists (AAPS) | News | Comments

An intestinal patch device containing insulin that can be swallowed in the form of a capsule, in development by researchers at University of California Santa Barbara, has demonstrated efficacy of blood glucose management in diabetic rats. Read more...


GSK Heart Drug Fails in Study; Shingles Vaccine Shows Benefits

October 27, 2015 10:13 am | by Stephanie Guzowski, Editor | News | Comments

GlaxoSmithKline’s experimental heart drug failed in the first part of a large clinical trial, the company said on Tuesday. In better news for GSK, the company's experimental shingles vaccine Shingrix succeeded in a second pivotal Phase 3 study. Read more...


The Role of the FDA's Office of Pharmaceutical Quality

October 27, 2015 9:43 am | by Ryan Bushey, Associate Editor | News | Comments

AAPS continued on Monday with a 90-minute presentation from three representatives at the Food and Drug Administration’s Office of Pharmaceutical Quality. Read more...


Scientists Discover a 'Switchboard' of Molecules that Protect Against Parkinson's Disease

October 27, 2015 9:40 am | by University of Dundee | News | Comments

A `switchboard' of molecules that play a vital role in protecting the brain against Parkinson's disease has been uncovered by a research team led by the University of Dundee. Read more...


Pipeline Update: The Emergence of Biosimilars

October 27, 2015 8:30 am | by Meg Snyder, Editor, Pharmaceutical Processing | Articles | Comments

Today’s pharmaceutical market is growing exponentially in potential. Not only has there been new brand-name and generic drugs produced for a myriad of medical conditions, but also the arrival of biosimilars in the United States. All of these changes only serve to engender a competitive environment, thriving on quantitative and qualitative productivity and rapidity, among manufacturers. Read more...


AAPS 2015: How to Properly Price Innovative Medicines

October 27, 2015 8:09 am | by Ryan Bushey, Associate Editor | News | Comments

The session examined how pharmaceutical companies can establish realistic drug prices that benefit the company as well as the consumer. Read more...


Researchers Discover an Epilepsy Switch

October 26, 2015 1:39 pm | by University of Bonn | News | Comments

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals. Read more...


Use of Benzodiazepines and Related Drugs Common around Alzheimer's Diagnosis

October 26, 2015 1:32 pm | by University of Finland | News | Comments

Benzodiazepines and related drugs are initiated frequently in persons with Alzheimer's disease already before the diagnosis, and their use becomes even more common after the diagnosis, shows a recent study from the University of Eastern Finland. Read more...


Stopping Tuberculosis Requires New Strategy

October 26, 2015 1:28 pm | by Harvard T.H. Chan School of Public Health | News | Comments

Unless there is a major shift in the way the world fights tuberculosis—from a reliance on biomedical solutions to an approach that combines biomedical interventions with social actions—the epidemic and drug resistance will worsen, say researchers at Harvard T.H. Chan School of Public Health. Read more...


WHO Removes Nigeria From List of Polio-Endemic Countries

October 26, 2015 1:23 pm | by Associated Press | News | Comments

The U.N. World Health Organization is formally removing Nigeria from the list of polio-endemic countries, meaning the entire African continent is free of the crippling disease. Read more....


Vertex, CRISPR Therapeutics to Collaborate on Gene Editing

October 26, 2015 12:39 pm | by Stephanie Guzowski, Editor | News | Comments

Vertex Pharmaceuticals announced on Monday a $105 million commitment to gene editing company CRISPR Therapeutics, setting its sights on a potential cure for cystic fibrosis (CF) and sickle cell disease. CRISPR uses the gene editing technology, CRISPR-Cas9. Read more...


Pharma Team Introduces $1 Pill in Response to Competitor’s $750 Jack-up

October 26, 2015 12:23 pm | by Seth Augenstein, Digital Reporter | News | Comments

The outrage over a pharmaceutical company’s decision to increase the cost of an infectious disease drug from $13.50 to $750 per pill rippled into the U.S. Presidential campaign, and has vilified a CEO who made the decision. Now it’s also caused a backlash from a competitor now marketing its own version of the treatment for just $1 per pill. Read more...


FDA Approves Yondelis for Two Common Subtypes of Soft Tissue Sarcoma

October 26, 2015 10:51 am | News | Comments

Janssen Biotech, Inc. today announced the U.S. Food and Drug Administration (FDA) has approved Yondelis (trabectedin) for the treatment of patients with unresectable (unable to be removed with surgery) or metastatic liposarcoma (LPS) or leiomyosarcoma (LMS) who received a prior anthracycline-containing regimen. Read more...


Valeant Board Forms Committee to Look into Philidor Ties

October 26, 2015 10:34 am | by Tom Murphy, AP Business Writer | News | Comments

Valeant Pharmaceuticals is forming a committee to delve into the drug company's relationship with the specialty pharmacy Philidor, which was the target of a scathing research report last week. Read more...



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