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DDD Update

Daily news and top headlines for drug research professionals

Study Reveals More Dangers of Smoking While Pregnant

January 30, 2015 9:37 am | by University of Aberdeen | News | Comments

Smoking while pregnant causes chemical changes to the DNA of a foetus detectable from as early as 12 weeks and may predispose children born to smokers to a range of health conditions which last throughout life. Read more...      

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Astellas, Immunomic Therapeutics Announce Licensing Agreement for Allergy Vaccine

January 30, 2015 9:32 am | News | Comments

The vaccine is designed to treat allergies induced by Japanese red cedar pollen. Read more...                            

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Hot on the Trail of the Hepatitis-Liver Cancer Connection

January 30, 2015 9:26 am | by Riken Institute | News | Comments

Scientists have for the first time demonstrated the profound effect that chronic hepatitis infection and inflammation can have on the genetic mutations found in tumors of the liver. Read more...           

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Hydrogen Sulfide Could Help Lower Blood Pressure

January 30, 2015 9:19 am | by University of Exeter | News | Comments

Research has indicated that a new compound, called AP39, could be beneficial in cases of high blood pressure and diseases of the blood vessels that occur with ageing and diabetes. Read more...            

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Dopamine Neurons Study Could Improve Mobility, Neurological Disorder Research

January 30, 2015 9:13 am | by University of Leicester | News | Comments

University team find for the first time when and why dopamine releasing cells in the forebrain are activated. Read more...                       

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Valeant Pharmaceuticals Selected as Lead Bidder to Acquire Dendreon

January 30, 2015 9:03 am | News | Comments

Valeant Pharmaceuticals announced that it has entered into a "stalking horse" asset purchase agreement to acquire certain assets of Dendreon Corporation and the company's immunotherapy treatment. Read more...         

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Needle Biopsies May Be Safe in Pancreatic Cancer

January 29, 2015 4:06 pm | by Cynthia Fox, Science Editor | Articles | Comments

Oncologists and patients who fear tumor needle biopsies—thinking they may cause tumor bits to break off and “seed” cancer elsewhere—may rest easier after reassuring Mayo Clinic news. Read more...                   

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New Biological Evidence Reveals Link Between Brain Inflammation, Depression

January 29, 2015 10:46 am | by Centre for Addiction and Mental Health | News | Comments

A new study by the Centre for Addiction and Mental Health (CAMH) found that the measure of brain inflammation in people who were experiencing clinical depression was increased by 30 percent. The findings, published today in JAMA Psychiatry, have important implications for developing new treatments for depression. Read more..

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Immune Cells are Ally, Not Enemy, in Battle Against Alzheimer's

January 29, 2015 10:33 am | by Yale University | News | Comments

Beta-amyloid is a sticky protein that aggregates and forms small plaques in the brains of the elderly and is thought to be a cause of Alzheimer's disease. Because specialized immune cells always surround these plaques, many have theorized that these cells are responsible for inflammation and damage to surrounding brain cells. Read more..

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New Approach to Delay Alzheimer's Onset to Be Tested

January 29, 2015 10:22 am | by Alzheimer's Drug Discovery Foundation | News | Comments

The Alzheimer's Drug Discovery Foundation (ADDF) announced a $900,000 grant to AgeneBio, a pharmaceutical company developing innovative therapies for neurologic and psychiatric diseases. Read more...                       

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3D Enzyme Model Provides New Tool for Drug Development

January 29, 2015 10:16 am | by UC San Diego | News | Comments

Phospholipase A2 (PLA2) enzymes are known to play a role in many inflammatory diseases, including asthma, arthritis and atherosclerosis. It then stands to reason that PLA2 inhibitors could represent a new class of anti-inflammatory medication. Read more...

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Arizona Monitoring Hundreds for Measles Linked to Disneyland

January 29, 2015 10:03 am | by Felicia Fonseca, Associated Press | News | Comments

A measles outbreak in Arizona that originated at California's Disney parks is at risk of increasing dramatically in size as health officials keep tabs on 1,000 people, including nearly 200 children who could have been exposed at a Phoenix-area medical center.

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AstraZeneca Announces New Genome Editing Collaborations

January 29, 2015 9:21 am | News | Comments

AstraZeneca announced four research collaborations aimed at harnessing the power of CRISPR, a pioneering genome-editing technique, across its entire discovery platform in the company’s key therapeutic areas. Read more...       

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Rotavirus Vaccine Reduces Severe Diarrhea by 64 Percent

January 29, 2015 9:12 am | by University of Liverpool | News | Comments

Researchers have found that diarrhoea caused by rotavirus infection is significantly reduced in the developing world with the use of a vaccine to prevent the condition. Read more...             

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Roche, Qualcomm to Collaborate on Remote Patient Monitoring

January 29, 2015 9:04 am | News | Comments

This is a strategic collaboration to improve remote monitoring and management of chronic disease patients. Read more...                        

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