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DDD Update

Daily news and top headlines for drug research professionals

The Prospect of Drugs to Treat Gluten Sensitivity

April 30, 2015 1:31 pm | by Stephanie Guzowski, Editor | News | Comments

Pharmaceutical companies are working to develop treatments as a first line of defense against gluten-sensitive symptoms — including abdominal pain, bloating, diarrhea, headaches and fatigue. Read more...

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Prostate Cancer Combination Treatment Could Beat Disease at Its Own Game: Early Study

April 30, 2015 10:23 am | by Seth Augenstein, Digital Reporter | News | Comments

Through chemoimmunotherapy, a chemical one-two punch, a team of doctors said they are now having new success in mouse models. Read more...

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Strong Link Found Between Dementia, Common Anticholinergic Drugs

April 30, 2015 9:41 am | by Cynthia Fox, Science Editor | Articles | Comments

There is a strong and possibly irreversible link between Alzheimer’s disease and many commonly used medications for insomnia, allergies, and depression, according to a large recent JAMA Internal Medicine study. Read more...

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Gene Variants Show Potential in Predicting Rheumatoid Arthritis Outcomes

April 29, 2015 4:29 pm | by University of Manchester | News | Comments

New cohort studies have shown that certain genetic variants are associated with higher or lower risks of increased disease severity. Read more...

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Biomarkers Could Predict Response to Antipsychotic Treatment

April 29, 2015 4:22 pm | by King's College London | News | Comments

Only half of patients with psychosis respond to current medications and there is still a lack of knowledge surrounding the factors causing this lack of response. Read more...

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Valeant Raises Outlook after Completing Purchase of Salix

April 29, 2015 4:18 pm | by The Associated Press | News | Comments

Valeant's biggest businesses include dermatology, eye health, and neurology. Read more...

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German Measles Officially Eliminated in North, South America

April 29, 2015 4:13 pm | by Mike Stobbe, AP Medical Writer | News | Comments

Vaccines against German measles were first licensed in 1969, and were included in mass vaccination campaigns. It is now part of childhood shots. Read more...

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Flu Kills Millions of Birds, May Spread to Humans

April 29, 2015 1:41 pm | by Seth Augenstein, Digital Reporter | News | Comments

A strain of avian flu that has spread to chickens and turkeys in the Midwest and caused the death of millions of birds could make the jump to humans in time for next flu season, according to the U.S. Department of Agriculture and the Centers for Disease Control and Prevention. Read more..

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FDA Accepts Otonomy's NDA for Middle Ear Effusion

April 29, 2015 12:27 pm | News | Comments

​Otonomy, Inc. a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapeutics for diseases and disorders of the inner and middle ear, today announced that its New Drug Application (NDA) for the approval of AuriProTM. Read more...

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Your Brain on Drugs: Functional Differences in Brain Communication in Cocaine Users

April 29, 2015 12:22 pm | by University of Texas Medical Branch | News | Comments

The brain function of people addicted to cocaine is different from that of people who are not addicted and often linked to highly impulsive behavior, according to a new scientific study. Read more...

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FDA Accepts BLA For Biogen, AbbVie MS Treatment

April 29, 2015 12:14 pm | News | Comments

Today Biogen and AbbVie announced that the U.S. Food and Drug Administration (FDA) has accepted for review the companies’ Biologics License Application (BLA) requesting marketing approval of ZINBRYTA (daclizumab high-yield process) for relapsing forms of multiple sclerosis (MS). Read more...

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FDA to Review Amgen's High Cholesterol Drug

April 29, 2015 11:58 am | News | Comments

Amgen announced that the Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC) of the U.S. Food and Drug Administration (FDA) will review data supporting the Company's Biologics License Application (BLA) for RepathaTM (evolocumab) for the treatment of high cholesterol at a meeting on June 10, 2015. Read more...

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Breaking Ground on Biologics

April 29, 2015 11:01 am | by Ryan Bushey, Associate Editor | Articles | Comments

One of the final sessions for the 2015 Experimental Biology Conference in Boston, Massachusetts was on biologics. Over the course of two and a half hours, a panel of scientists and experts discussed their research and where they see opportunity in this field. Read more...

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3 Ways Technology is Changing the Face of Drug Discovery & Development

April 29, 2015 9:04 am | by Merrilyn Datta, PhD, President and General Manager, Definiens | Articles | Comments

While personalized medicine has been a goal for some time, there have been several obstacles. Although there has been an explosion in genomic data, the corresponding clinical utility for this data has been slow to be validated. Read more...

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World Malaria Day Brings Scourge into Spotlight

April 29, 2015 8:35 am | by Seth Augenstein, Digital Reporter | News | Comments

Malaria kills more than half a million people each year worldwide – and that’s after dramatic declines over the last decade. Read more...

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