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Daily news and top headlines for drug research professionals

Epigenetic Driver of Glioblastoma Provides New Therapeutic Target

July 7, 2015 9:57 am | by Heather Buschman, PhD, UC, San Diego | News | Comments

 Using human tumor samples and mouse models, researchers at University of California, San Diego School of Medicine and Moores Cancer Center discovered that cancer stem cell properties are determined by epigenetic changes — chemical modifications cells use to control which genes are turned on or off. Read more...

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Suppressing the Immune Response May Lead to More Potent Vaccines, Study Finds

July 7, 2015 9:51 am | by Ziba Kashef, Yale University | News | Comments

Yale researchers uncovered a new role for a type of immune cell, known as regulatory T cells, in promoting long-term immunity. The new insight gets researchers one step closer to developing vaccines that could be more protective against some of the most intractable viral infections, including HIV and flu. Read more...

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Study Identifies New Way to Kill the Malaria Parasite

July 7, 2015 9:46 am | by University of Leicester | News | Comments

Scientists have discovered new ways in which the malaria parasite survives in the blood stream of its victims, a discovery that could pave the way to new treatments for the disease. Read more...

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Allergan, Merck Enter into Licensing Agreement for Migraine Program

July 7, 2015 9:21 am | News | Comments

Allergan plc and Merck, known as MSD outside the United States and Canada, today announced that they have entered into an agreement under which Allergan will acquire the exclusive worldwide rights to Merck's investigational small molecule oral calcitonin gene-related peptide (CGRP) receptor antagonists. Read more...

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The Next Anti-Tuberculosis Drug May Already Be in Your Local Pharmacy

July 7, 2015 9:07 am | by Ecole Polytechnique Federale De Lausanne | News | Comments

Testing thousands of approved drugs, EPFL scientists have identified an unlikely anti-tuberculosis drug: the over-the-counter antacid lansoprazole (Prevacid). Read more...

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Cancer Drug 49 Times More Potent than Cisplatin

July 7, 2015 8:59 am | by University of Warwick | News | Comments

Tests have shown that a new cancer drug, FY26, is 49 times more potent than the clinically used treatment Cisplatin. Read more...

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Foreigner in Philippines Tests Positive for MERS Virus

July 6, 2015 3:46 pm | by The Associated Press | News | Comments

At least seven other people who had close contact with the patient were under home quarantine. Read more...

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Arthritis Drug Could Be Used to Treat Blood Cancer Sufferers

July 6, 2015 3:38 pm | by University of Sheffield | News | Comments

MTX is commonly used at low doses to treat inflammatory diseases including rheumatoid arthritis, Crohn's disease and psoriasis and has few side effects. Read more...

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Benefits of Vitamin B12 Supplements for Older People Questioned

July 6, 2015 3:13 pm | by University of Oxford | News | Comments

The researchers found no evidence of improved neurological or cognitive function among people who received vitamin B12 compared to those who received the placebo tablets. Read more...

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Innovation in Healthcare: How Are We Willing to Pay for Disruption?

July 6, 2015 3:03 pm | by Yogesh Soneji, Principal, Trinity Partners | Articles | Comments

Innovation in healthcare is at a record level – but so is its cost.  The number of novel drugs approved between 2011 and 2015 was more than 40 percent higher than in the previous five years. With certain therapies approaching a $1 million-plus price tag, it’s time to ask: will innovation eventually get stifled or can companies reimagine their business models? Read more...

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New Drug Helps Improve Sunshine Tolerance for Patients with Rare Disease

July 6, 2015 12:38 pm | by Ryan Bushey, Associate Editor | Articles | Comments

An estimated 5,000 to 10,000 people suffer from this condition worldwide with it typically appearing in early childhood. Read more...

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Midlife Changes in Alzheimer's Biomarkers May Predict Dementia

July 6, 2015 11:31 am | by Washington University School of Medicine | News | Comments

Studying brain scans and cerebrospinal fluid of healthy adults, scientists have shown that changes in key biomarkers of Alzheimer's disease during midlife may help identify those who will develop dementia years later, according to new research. Read more...

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Vanda: Listing of New Hetlioz Patent in FDA Orange Book

July 6, 2015 11:15 am | News | Comments

Vanda Pharmaceuticals Inc. (Vanda) today announced that a Hetlioz patent, number 9,060,995 ('995 patent), is now listed in the U.S. Food and Drug Administration publication Approved Drug Products With Therapeutic Equivalence Evaluations, commonly known as the Orange Book. Read more..

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Uncovering the Mechanism of Our Oldest Anesthetic

July 6, 2015 11:09 am | News | Comments

MIT researchers reveal brainwave changes in patients receiving nitrous oxide, or “laughing gas.” Read more...

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Basic Beliefs About Atherosclerosis Overturned

July 6, 2015 10:59 am | by University of Virginia Health System | News | Comments

Doctors’ efforts to battle the dangerous atherosclerotic plaques that build up in our arteries and cause heart attacks and strokes are built on several false beliefs about the fundamental composition and formation of the plaques, new research from the University of Virginia School of Medicine shows. Read more..

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