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DDD Update

Daily news and top headlines for drug research professionals

Children's Relentless Seizures Halted By New Drug

November 24, 2014 12:22 pm | by Marla Paul, Northwestern University | News | Comments

An investigational medication has been found to effectively treat children with life-threatening and difficult-to-control epileptic seizures without side effects. Read more...              

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Amgen-Sponsored Gastric Cancer Studies Terminated

November 24, 2014 11:01 am | News | Comments

Amgen announced the termination of all Amgen-sponsored clinical studies of rilotumumab in advanced gastric cancer,  including the Phase 3 RILOMET-1 and RILOMET-2 studies. Read more...                                 

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Merck, NewLink Genetics To Collaborate for Ebola Vaccine

November 24, 2014 10:45 am | News | Comments

Merck, known as MSD outside the United States and Canada, and NewLink Genetics Corporation, announced that they have entered into an exclusive worldwide license agreement to research, develop, manufacture, and distribute NewLink’s investigational rVSV-EBOV (Ebola) vaccine candidate. Read more... 

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EU Approves Novartis' Signifor Drug for Rare Hormonal Disorder

November 24, 2014 10:38 am | News | Comments

Novartis announced today that the European Commission has approved Signifor (pasireotide) as a new long acting release formulation for once monthly intramuscular injection to treat adult patients with acromegaly for whom surgery is not an option or has not been curative and who are inadequately controlled on treatment with a first-generation somatostatin analogue (SSA).  Read more...

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U.S. Looking Past Ebola to Prepare for Next Outbreak

November 24, 2014 9:25 am | by Lauran Neergaard, AP Medical Writer - Associated Press | News | Comments

The next Ebola or the next SARS. Maybe even the next HIV. Even before the Ebola epidemic in West Africa is brought under control, public health officials are girding for the next health disaster. Read more...                 

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Plague Outbreak Kills 40 People in Madagascar

November 24, 2014 9:20 am | by Lynsey Chutel - Associated Press | News | Comments

A plague outbreak has killed 40 people on the island nation of Madagascar, with 119 people diagnosed with the bacterial disease since August. Read more...                                                                                

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Health Care M&A Leads Global Deal Surge

November 24, 2014 9:17 am | by Linda A. Johnson and Steve Rothwell, AP Business Writers - Associated Press | News | Comments

In a big year for deal making, the health care industry is a standout. Large drugmakers are buying and selling businesses to control costs and deploy surplus cash. A rising stock market, tax strategies and low interest rates are also fueling the mergers and acquisitions. Read more...

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Neurotrope: Last Patient Dosed in Phase 2a Alzheimer's Study

November 21, 2014 11:41 am | News | Comments

Neurotrope, Inc. announced that the last patient has been dosed in its Phase 2a clinical trial of Bryostatin-1 for the treatment of patients with Alzheimer's disease (AD). The trial is being conducted under an Investigational New Drug (IND) application filed by the Company's licensor, the Blanchette Rockefeller Neuroscience Institute (BRNI). Read more...

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Researcher Who Found Cause of Lyme Disease Dies

November 21, 2014 11:32 am | by Associated Press | News | Comments

The Swiss-born researcher who gained international recognition for discovering the bacteria that causes Lyme disease has died in western Montana. A spokesman at the Daly-Leach Chapel said Wilhelm "Willy" Burgdorfer died from complications of Parkinson's disease Monday in Hamilton. He was 89. Read more...

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FDA Approves New, Hard-to-Abuse Hydrocodone Pill

November 21, 2014 11:27 am | by Matthew Perrone, AP Health Writer - Associated Press | News | Comments

Federal health regulators on Thursday approved the first hard-to-abuse version of the painkiller hydrocodone, offering an alternative to a similar medication that has been widely criticized for lacking such safeguards. Read more...

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Powerful Method to Speed Cancer Drug Discovery

November 21, 2014 11:22 am | by Salk Institute | News | Comments

For decades, researchers have struggled to translate basic scientific discoveries about cancer into therapeutics that effectively–and with minimal side effects–shrink a tumor. Read more...

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Soaring Generic Drug Prices Draw Senate Scrutiny

November 21, 2014 11:10 am | by Matthew Perrone, AP Health Writer - Associated Press | News | Comments

Some low-cost generic drugs that have helped restrain health care costs for decades are seeing unexpected price spikes of up to 8,000 percent, prompting a backlash from patients, pharmacists and now Washington lawmakers. Read more...

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HIV/AIDS Drugs Could Be Repurposed to Treat AMD

November 21, 2014 11:01 am | by Ann Blackford, University of Kentucky | News | Comments

A study published in the journal Science by an international group of scientists, led by the laboratory of Dr. Jayakrishna Ambati, professor and vice chair of the Department of Ophthalmology & Visual Sciences at the University of Kentucky, reports that HIV/AIDS drugs that have been used for the last 30 years could be repurposed to treat AMD. Read more...

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AbbVie Acquires Manufacturing Facility in Singapore

November 21, 2014 10:04 am | News | Comments

The facility will expand the company's global operations for small molecule and biologics manufacturing. Read more...                        

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UK Investment to Develop Lung Cancer Drugs

November 21, 2014 9:58 am | News | Comments

A new collaboration in the UK will develop a promising class of cancer inhibitors. Read more...                            

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