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DDD Update

Daily news and top headlines for drug research professionals

Fast Synthesis Could Boost Drug Development

March 19, 2014 3:10 pm | News | Comments

A major bottleneck has prevented peptide drugs from reaching their full potential: Manufacturing the peptides takes several weeks. But that bottleneck may soon disappear, as a team of chemists has designed a way to manufacture peptides in mere hours. Read more...

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Team Proposes New Model for Clinical Trials

March 19, 2014 3:01 pm | News | Comments

Experts across academia, industry and government propose a new method for health care providers to get the right treatments to the right patients at the right time. Read more...                     

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FDA Approves First Mixed Protocol IVF Treatment

March 19, 2014 2:52 pm | News | Comments

Ferring Pharmaceuticals Inc. announced FDA approval of new labeling for their fertility products, MENOPUR and BRAVELLE. Read more...                                  

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Isis Initiates Phase 1 Hyperlipidemia Drug Trial

March 19, 2014 2:41 pm | News | Comments

Isis Pharmaceuticals announced that it has initiated a Phase 1 clinical study for ISIS-ANGPTL3Rx, an antisense drug targeting angiopoietin-like 3 protein (ANGPTL3), an independent risk factor for cardiovascular disease. Read more...      

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Meningitis Death Tied to Princeton Outbreak Strain

March 19, 2014 2:34 pm | by Kathy Matheson | News | Comments

A Philadelphia college student died of the same type of meningitis that caused an outbreak at Princeton University in New Jersey, suggesting the strain might still exist on the Ivy League campus despite a massive vaccination effort. Read more... 

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Room-Temp Spray Vaccine May Curb Diseases in Remote Areas

March 19, 2014 11:02 am | News | Comments

A new kind of single-dose vaccine that comes in a nasal spray and doesn’t require refrigeration could dramatically alter the public health landscape, get more people vaccinated around the world and address the looming threats of emerging and re-emerging diseases. Read more...

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Dartmouth, Aeras Conducting Study of New TB Vaccine

March 19, 2014 10:53 am | News | Comments

Dartmouth's Geisel School of Medicine and Aeras, a global nonprofit biotech, announced a collaboration to jointly conduct a trial of a new vaccine against tuberculosis (TB). Read more...                   

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Novo Nordisk Hemophilia Drug Excels in Phase 3

March 19, 2014 10:42 am | News | Comments

Novo Nordisk announced the completion of pathfinderT2, the first Phase 3 trial with long-acting recombinant factor VIII, N8-GP (turoctocog alfa pegol) for hemophilia A patients. Read more...                  

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Cardiome Finds Distributor for Brinavess Heart Drug in Spain

March 19, 2014 10:18 am | News | Comments

Cardiome Pharma Corp. announced that the company has entered into a distribution agreement with Logista Pharma S.A., headquartered in Madrid, Spain, to distribute Brinavess (vernakalant IV) within the Spanish market. Read more...      

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Horizon Pharma to Acquire Vidara for $660M

March 19, 2014 9:24 am | News | Comments

Horizon Pharma Inc. plans to buy the privately held Vidara Therapeutics International Ltd. in a cash-and-stock deal that will add the immune system disorder drug Actimmune to the specialty drugmaker's product portfolio. Read more...        

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Astellas, Daiichi Sankyo Form Compound Library Sharing Program

March 19, 2014 1:21 am | by Daiichi Sankyo | News | Comments

Astellas Pharma and Daiichi Sankyo announced the companies would form a compound library sharing partnership for approximately 400,000 selected compounds. This is the first time that a compound library partnership of this scale has been formed in Japan. Read more...

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New Therapeutic Target Discovered for Alzheimer’s

March 18, 2014 3:09 pm | News | Comments

A team of scientists is reporting that cathepsin B gene knockout or its reduction by an enzyme inhibitor blocks creation of key neurotoxic pGlu-A-beta peptides linked to Alzheimer’s disease. Read more...              

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Scientists Slow Development of Cell-Killing Alzheimer's Plaques

March 18, 2014 2:58 pm | News | Comments

Researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major cause of the disease. Read more...               

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Dog DNA Plays Role in Developing New Human Therapies

March 18, 2014 2:35 pm | News | Comments

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a new proof-of-concept study. Read more...                           

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An End to Animal Testing for Drug Discovery?

March 18, 2014 2:15 pm | News | Comments

As some countries and companies roll out new rules to limit animal testing in pharmaceutical products designed for people, scientists are stepping in with a new way to test therapeutic drug candidates and determine drug safety and drug interactions— without using animals. Read more...

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