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DDD Update

Daily news and top headlines for drug research professionals

Study Will Test Survivors' Blood to Treat Ebola

November 19, 2014 9:19 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Plasma from survivors contains antibodies, substances the immune system makes to fight the virus. Read more...                         

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New Insight Into Cells Could Lead to Better Drugs

November 19, 2014 9:11 am | News | Comments

Researchers investigated how different types of immune cells communicate with each other – and how they kill cancerous or infected cells. Read more...                   

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Reprogramming Cells, Long Term

November 18, 2014 2:07 pm | by B. D. Colen, Harvard Staff Writer | News | Comments

Harvard Stem Cell Institute (HSCI) researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology (MIT), have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period. Read more...

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Pfizer's Meningococcal Group B Vaccine Is Now Available

November 18, 2014 1:58 pm | News | Comments

Pfizer Inc. announced that Trumenba (Meningococcal Group B Vaccine) is now available for order by healthcare providers in the United States. Read more...

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Anti-Leukemia Drug May Also Work Against Ovarian Cancer

November 18, 2014 1:50 pm | News | Comments

An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine in a study. Read more...

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‘Big Data’ Approach to Help Pinpoint New Stent Drug

November 18, 2014 1:40 pm | by Tracie White, Stanford University | News | Comments

Replacing the current drug used to coat artery-opening stents with a drug more targeted to the actual cause of stent disease could reduce blood clots and heart attacks, researchers say. Read more...

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Strategy: Physicians Prescribe More Generics, Less Brand Name Drugs

November 18, 2014 1:19 pm | News | Comments

Programming electronic health records to make generic drugs the default choice when physicians write prescriptions may offer one way to reduce unnecessary spending and improve health care value in the face of spiraling U.S. health expenditures, according to a new study. Read more...

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Society for Neuroscience Annual Meeting Showcases Strides in Exploring the Brain

November 18, 2014 10:56 am | by Christina Jakubowski, Managing Editor, Bioscience Technology | Articles | Comments

More than 30,000 brain advocates from academia, industry and media converged on Washington, D.C. this week for the 44th annual meeting of the Society for Neuroscience (SfN). Read more...

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Weak Spots in Ebola's Defenses

November 18, 2014 10:26 am | by Scripps Institute | News | Comments

Scientists at The Scripps Research Institute (TSRI) have identified weak spots on the surface of Ebola virus that are targeted by the antibodies in ZMapp, the experimental drug cocktail administered to several patients during the recent Ebola outbreak. Read more...

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Merck's Cholesterol-Lowering Drug Reduces Heart Problems

November 18, 2014 10:22 am | News | Comments

Merck, known as MSD outside the United States and Canada, announced that the investigational IMPROVE-IT study met its primary and all secondary composite efficacy endpoints.  Read more...

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Preferred Drug Regimen for Preventing Mother-to-Child HIV Transmission

November 18, 2014 10:14 am | News | Comments

For HIV-infected women in good immune health, taking a three-drug regimen during pregnancy prevents mother-to-child HIV transmission more effectively than taking one drug during pregnancy, another during labor and two more after giving birth, an international clinical trial has found. Read more...

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Novartis' Drug Could Change Course of Heart Failure for Patients

November 18, 2014 9:57 am | News | Comments

New data on Novartis' investigational medicine, LCZ696, for patients with heart failure with reduced ejection fraction (HFrEF) shows it has the potential to change the course of the disease for patients. Read more...

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Journal Watch: Top 100 Cited Papers of All Time

November 18, 2014 9:52 am | by Drug Discovery & Development Staff | Articles | Comments

In honor of the SCI’s 50th anniversary, the journal Nature asked Thomson Reuters for the 100 most highly cited papers of all time.  Read more...                                  

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Actavis to Buy Allergan for $66B

November 17, 2014 2:34 pm | by Tom Murphy - AP Business Writer | News | Comments

Actavis will pay $66 billion to buy fellow drugmaker Allergan in a deal that could finally end a months-long takeover push from Valeant Pharmaceuticals. Read more...                

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Roche Announces FDA Approval of Ovarian Cancer Treatment

November 17, 2014 1:30 pm | News | Comments

The FDA approves Roche's ovarian cancer treatment. Read more...                                 

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