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DDD Update

Daily news and top headlines for drug research professionals

AstraZeneca, QIAGEN Collaborate on Iressa Diagnostic Test

July 28, 2014 12:38 pm | News | Comments

AstraZeneca announced that it has entered into a collaboration with Netherlands-based QIAGEN to develop a non-invasive diagnostic test to identify non-small cell lung cancer patients who are suitable for treatment with Iressa. Read more...    

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Scientists Discover New Mechanism of Drug Resistance

July 28, 2014 12:31 pm | News | Comments

Microorganisms can evade treatment by acquiring mutations in the genes targeted by antibiotics or antifungal drugs. Now, a new study has shown that microorganisms can use a temporary silencing of drug targets to gain the benefits of drug resistance without the commitment. Read more...

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Cancer Drug Shows Promise as Infertility Treatment

July 28, 2014 12:26 pm | News | Comments

Physicians may have a new drug to treat infertility in women with polycystic ovary syndrome, according to a national, multi-center clinical trial. Read more...                          

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HIV Inhibitor May Also Block Herpes Infection

July 28, 2014 12:19 pm | News | Comments

Creating a successful vaccine against two members of the herpes virus family, the sexually transmitted herpes simplex virus 1 (HSV-1) and 2 (HSV-2), has proven to be challenging. But now, a clinical trial, based on an HSV-2 vaccine, is being conducted. Read more...

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MedImmune Fights Pediatricians' New Advice

July 28, 2014 12:13 pm | by Lindsey Tanner, AP Medical Writer | News | Comments

A costly drug given mostly to premature babies is at the center of a clash between the manufacturer and the nation's leading pediatrician's group, which recommends scaling back use of the medicine. Read more...            

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FDA Clears IND for Lorus Blood Cancer Drug

July 28, 2014 10:53 am | News | Comments

Lorus Therapeutics Inc. announced that the FDA completed its review and cleared the company's IND application of LOR-253 for the treatment of hematologic malignancies including acute myeloid leukemia, high-risk myelodysplastic syndromes, lymphomas and multiple myeloma. Read more...

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Veloxis Gets EU Marketing Authorization for Transplant Drug

July 28, 2014 10:47 am | News | Comments

Veloxis Pharmaceuticals A/S and Chiesi Farmaceutici S.p.A. announced that the European Commission (EC) has granted marketing authorization for Envarsus for the prevention of organ rejection in adult kidney and liver transplant patients in the European Union (EU). Read more...

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AstraZeneca, Roche Collaborate on Companion Diagnostic Test

July 28, 2014 10:41 am | News | Comments

AstraZeneca announced it has entered into collaboration with Roche to develop a plasma-based companion diagnostic test to support AZD9291, AstraZeneca’s investigational compound in clinical development for non-small-cell lung cancer (NSCLC). Read more...

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COSMOS Results Published on World Hepatitis Day

July 28, 2014 10:35 am | News | Comments

Medivir AB announced that results from the phase 2 COSMOS clinical study were published in The Lancet, demonstrating that 92% of genotype 1 chronic hepatitis C virus adult patients treated with simeprevir in combination with sofosbuvir achieved sustained virologic response 12 weeks after the end of treatment. Read more...

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Emulate to Commercialize Organs-on-Chips Platform

July 28, 2014 10:25 am | News | Comments

Emulate Inc. announced the company’s launch with a $12 million Series A financing to commercialize a first-in-kind, automated ‘Organs-on-Chips’ platform that mimics human physiology and diseases, while permitting real-time elucidation of molecular mechanisms of action and toxicity. Read more...

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Liberia’s President Tries to Contain Ebola Outbreak

July 28, 2014 10:17 am | by Jonathan Paye-Layleh, Associated Press | News | Comments

Liberia's president has closed all but three land border crossings, restricted public gatherings and quarantined communities heavily affected by the Ebola outbreak in the West African nation, which has killed 129 people in the country and more than 670 across the region. Read more...

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Novel Magnetic Technology Enhances Bioseparations

July 25, 2014 5:18 pm | Product Releases | Comments

AMSBIO announces MagSi-Direct - a novel technology that brings the power, simplicity, and convenience of magnetic separation to researchers involved in cell biology, protein chemistry, flow cytometry, diagnostics development and many other fields. Read more...

ChIP Sequencing Kit for Next Generation Sequencing

July 25, 2014 4:16 pm | Product Releases | Comments

Porvair Sciences has developed a new ChIP sequencing assay kit extending the benefits of their proprietary Chromatrap solid state ChIP technology to preparation of purified Chromatin for the generation of sequencing libraries. Read more...

Thermo Fisher Scientific Reimagines UHPLC

July 25, 2014 3:46 pm | Product Releases | Comments

Thermo Fisher Scientific unveiled a new high performance liquid chromatography system designed from the ground up to provide new levels of performance, productivity and usability when used as a standalone system or with the latest mass spectrometers. Read more...

Panel Backs Extended Use of Allergan's DME Treatment

July 25, 2014 2:53 pm | News | Comments

Allergan announced that the European Union's Committee for Medicinal Products for Human Use has recommended extending the Marketing Authorization for Ozurdex to treat adult patients with vision loss due to diabetic macular edema. Read more...   

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