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DDD Update

Daily news and top headlines for drug research professionals

U.S. Steps Up Response As Ebola Worries Grow

October 16, 2014 10:06 am | by Jim Kuhnhenn | News | Comments

The revelation that a second Dallas nurse who is ill with Ebola was cleared to fly the day before her diagnosis raised new alarms as leaders of the nation's public health system prepared to defend their efforts to contain the deadly virus before a congressional hearing. Read more...

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NIH Awards $640,000 to Improve Diagnosis of Diseases

October 16, 2014 9:52 am | News | Comments

A two-year grant from the NIH will fund work by a Purdue Research Park-based company to improve methods to screen blood plasma samples for biomarkers, which are measurable indicators of a disease, to expedite diagnosis and treatment. Read more...

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Noven Announces Menopause Drug's Effects on Weight, Sexual Function

October 15, 2014 1:33 pm | News | Comments

Noven Pharmaceuticals Inc., announced the publication of data on the effects of low-dose mesylate salt of paroxetine (LDMP), marketed as Brisdelle (paroxetine) capsules, 7.5 mg, in Menopause, the peer-reviewed, scientific journal of The North American Menopause Society (NAMS). Read more...

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FDA: Little Evidence to Drop Chantix Boxed Warning

October 15, 2014 1:22 pm | by Matthew Perrone, AP Health Writer | News | Comments

Federal regulators say Pfizer has provided low-quality evidence to support its request to remove a bold-letter warning from its anti-smoking drug Chantix about suicidal behavior. Read more...

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Study Finds Neurons "Fine Tune" At Genetic Level

October 15, 2014 1:16 pm | News | Comments

Neurons are electrically charged cells in the nervous system that interpret and transmit information using electrical and chemical signals. A neuron’s electrical charge is determined by the flow of ions – charged atoms – in and out of the cell through pores, called ion channels. Read more...

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Shire Says AbbVie Should Proceed with $55B Buyout

October 15, 2014 1:05 pm | by Tom Murphy | News | Comments

The drugmaker Shire wants AbbVie to stick with its roughly $55 billion acquisition bid, and it is reminding its U.S. counterpart of the hefty breakup fee it could receive if things don't work out. Read more...

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DNA-based ‘Nano-Cocoons’ Attack, Kill Cancer Cells

October 15, 2014 12:55 pm | News | Comments

Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale “cocoons” made of DNA that target cancer cells and trick the cells into absorbing the cocoon before unleashing anticancer drugs. Read more...

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Ex-Financial Analyst at Merck Faces Insider Trading Charge

October 15, 2014 12:43 pm | News | Comments

A former senior finance analyst at Merck & Co. is facing an insider trading charge after authorities said that he passed secrets to a friend he met at college that earned $722,000 in illegal profits. Read more...

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How Plasma Transfusions From Survivors Fight Ebola

October 15, 2014 10:55 am | by Marilynn Marchione | News | Comments

A Dallas nurse being treated for Ebola has received a plasma transfusion from a doctor who beat his own infection with the deadly virus after getting a similar treatment. The reason: Antibodies in the blood of a survivor may help a patient fight off the germ. Read more...

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Eisai's Thyroid Cancer Drug Gets FDA Priority Review

October 15, 2014 10:45 am | News | Comments

Eisai Inc. announced that the FDA has accepted for review the NDA for its in-house developed agent lenvatinib mesylate as a treatment for progressive RAI-refractory DTC and granted the NDA Priority Review status. Read more...

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Clinical Conductor Takes Aim at Optimizing Oncology Clinical Trials

October 15, 2014 10:38 am | News | Comments

 The team behind Clinical Conductor is proud to announce brand new enhancements to the industry-leading CTMS. This first oncology focused release of several in the coming quarters adds a multitude of advanced features and functionalities designed to optimize the management and execution of oncology studies at organizations of all sizes and makeups.Read more...

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Selecta, JDRF, Sanofi Collaborate on SVP Immunotherapy for Type 1

October 15, 2014 10:31 am | News | Comments

Selecta Biosciences and JDRF, announced that they have extended their joint research collaboration and attracted Sanofi as a partner in support of their program to develop an SVP immunotherapy with the long-term goal to treat and potentially prevent the underlying cause of type 1 diabetes. Read more...

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2nd Person Tests Positive for Ebola

October 15, 2014 10:21 am | by Emily Schmall and Nomaan Merchant | News | Comments

 A second Dallas hospital worker who provided care for the first Ebola patient diagnosed in the U.S. has tested positive for the disease, pointing to lapses beyond how one individual may have donned and removed personal protective garb. Read more...     

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Reversing Idiopathic Pulmonary Fibrosis

October 15, 2014 10:14 am | by Cynthia Fox, Science Editor | News | Comments

Lethal fibrosis in lungs of idiopathic pulmonary fibrosis (IPF) mouse models can be reversed, say Yale University researchers. Read more...                                      

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Combating Bladder Cancer With Approved Drug

October 14, 2014 1:53 pm | News | Comments

A drug that activates targets of the hedgehog signaling pathway, which is lost when bladder cancer invades, could prevent the progression of the disease in humans. Clinical trials are planned. Read more...                  

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