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DDD Update

Daily news and top headlines for drug research professionals

Gene Therapy Makes Near-Blind Patients See by Strengthening Neural Connections

July 29, 2015 10:13 am | by Cynthia Fox, Science Editor | Articles | Comments

Gene therapy restored vision to blind patients by strengthening visual pathways from the retina, through the brain’s white matter, into the brain’s visual cortex, says a report in Science Translational Medicine. Read more...

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Naturally Occurring Protein Fragment Found in Brain Inhibits Key Enzyme Implicated In Alzheimer's

July 29, 2015 10:04 am | by UCLA | News | Comments

For the first time, UCLA researchers have shown that a natural protein fragment produced in the brain can act as an inhibitor of a key enzyme implicated in the onset of Alzheimer's disease, a finding that could lead to the development of new drugs to treat the disease. Read more...

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Closing the Gap on Developing a Vaccine for Middle Ear Infections

July 29, 2015 10:00 am | by Griffith University | News | Comments

Researchers from Griffith University's Institute for Glycomics, together with the Nationwide Children's Hospital in Ohio, have uncovered groundbreaking evidence to help vaccine developers prevent middle ear infections. Read more...

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Boehringer Ingelheim to Collaborate with Hanmi Pharmaceutical to Develop Lung Cancer Therapy

July 29, 2015 9:51 am | News | Comments

Boehringer Ingelheim and Hanmi Pharmaceutical Co., Ltd. today announced an exclusive license and collaboration agreement for the development and global commercialization rights, except South Korea, China and Hong Kong, of HM61713, a novel 3rd generation EGFR targeted therapy for the treatment of a specific type of lung cancer. Read more...

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Study Identifies 'Major Player' in Skin Cancer Genes

July 29, 2015 9:46 am | by Yale University | News | Comments

A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies. Read more...

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Four-Pronged Flu Prevention

July 29, 2015 9:39 am | by Lindsay Hock, Editor | Articles | Comments

Now, (July/August) is the time frame when flu vaccines start to be delivered to protect the public for next year. Yet, the road to an efficient vaccine is a difficult one. Just as with any virus, influenza mutates in its genetic material, potentially causing changes in the strains present each year. Read more...

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Gilead Beats Street 2Q Forecasts on Surge in Sales, Profit

July 29, 2015 9:22 am | by Linda A. Johnson, AP Business Writer | News | Comments

Blockbuster hepatitis C medicine Harvoni propelled Gilead Sciences Inc.'s second-quarter profit up 23 percent as total revenue for the biotech drugmaker jumped 26 percent and it raised its 2015 sales forecast for the second time. Its shares jumped in after-hours trading. Read more...

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Drugmaker GSK Sees Earnings Growth Returning in 2016

July 29, 2015 8:45 am | by The Associated Press | News | Comments

Synergy benefits are expected when the transaction begins to contribute more meaningfully. Read more...

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Merck Tops Street 2Q Forecasts Despite Lower Sales, Profits

July 29, 2015 8:41 am | by Linda A. Johnson, AP Business Writer | News | Comments

The company noted experimental hepatitis C combination pill grazoprevir/elbasvir is now being reviewed by regulators in the U.S. and European Union. Read more...

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Experimental MERS Vaccine Shows Promise in Animal Studies

July 29, 2015 8:40 am | by NIAID | News | Comments

A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques. Read more...

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Roche's Atezolizumab Could Spur Long-Awaited Bladder Cancer Treatment Innovation

July 29, 2015 8:40 am | by Cai Xuan, Ph.D., Oncology and Hematology, GlobalData | Articles | Comments

This observation opens up a market for companion biomarker tests that can be used to identify patients who would likely benefit from PD-1/PD-L1-targeted therapies. Read more...

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Quality Standards for Pharma

July 29, 2015 8:37 am | by Lindsay Hock, Editor | Articles | Comments

 Little do we think of the testing behind the medications prescribed to us that improve the quality of our lives. Yet, stringent testing is needed for any pharmaceutical or health care product to hit the shelves of your local convenience store. Read more...

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ANI Pharmaceuticals, Sofgen Announce FDA Approval of Nimodipine 30mg Capsules

July 28, 2015 1:00 pm | News | Comments

ANI Pharmaceuticals, Inc. ("ANI") today announced that its ANDA collaboration partner Sofgen has received approval from the U.S. Food and Drug Administration (FDA) of the Abbreviated New Drug Application (ANDA) for Nimodipine 30mg Capsules.  Read more...

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FDA Grants Breakthrough Therapy Designation to Eisai's Lenvatinib

July 28, 2015 12:58 pm | News | Comments

Eisai Inc. announced today the U.S. Food and Drug Administration (FDA) granted lenvatinib, the company's multiple receptor tyrosine kinase inhibitor, Breakthrough Therapy designation for the investigational use in patients with advanced or metastatic renal cell carcinoma (RCC) who were previously treated with a vascular endothelial growth factor (VEGF)-targeted therapy. Read more...

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Analysts Expect More Tie-Ups in Generic Drug Business

July 28, 2015 12:45 pm | by Associated Press | News | Comments

Analysts say they expect more tie-ups are coming in the generic drug industry in the wake of Teva's mammoth deal for the generic drug business of Allergan. Read more...

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