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DDD Update

Daily news and top headlines for drug research professionals

Potential New Drug Target for the Treatment of Rheumatoid Arthritis

May 21, 2015 1:40 pm | News | Comments

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints. Read more...

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New Data on Boehringer Ingelheim's COPD Treatment

May 21, 2015 1:30 pm | News | Comments

Boehringer Ingelheim announced new data analyses from the pivotal Phase III TONADO 1&2 studies (NCT01431274/NCT01431287), which explored the efficacy and safety of investigational tiotropium/olodaterol delivered via the Respimat inhaler for chronic obstructive pulmonary disease (COPD) compared to the individual components (tiotropium and olodaterol delivered by the RESPIMAT inhaler) alone. Read more...

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Novartis Announces COPD Phase 3 Results

May 21, 2015 1:23 pm | News | Comments

Today, Novartis announced for the first time detailed results from its phase III EXPEDITION trial program for QVA149 (indacaterol/glycopyrronium) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD). Read more...

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Emmes Announces FDA Clearance of New Medical Device

May 21, 2015 1:18 pm | News | Comments

The Emmes Corporation today announced that the U.S. Food and Drug Administration (FDA) has given marketing clearance for a new device that allows doctors to more accurately assess children's weight without the use of a weight scale. Weight estimates are used in emergency situations and in developing countries where scales may not be available. Read more...

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Injected T Cells from Bone Marrow Treat Multiple Myeloma, Pilot Study Finds

May 21, 2015 1:12 pm | by Stephanie Guzowski, Editor | Articles | Comments

In a first small clinical trial of its kind, researchers harnessed T cells from patients’ own bone marrow to treat multiple myeloma and provide immune protection for up to a year, according to a study published this week in Science Translational Medicine. Read more...

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FDA Proposes to Know More About Antibiotic Use in Animals

May 21, 2015 9:51 am | by Mary Clare Jalonick, Associated Press | News | Comments

The Food and Drug Administration is moving to collect more information on antibiotics used in animals that become meat. It's an effort to stem antibiotic-resistant diseases. Read more...

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Researchers Discover a Treatment to Block MS Progression

May 21, 2015 9:46 am | by University of Montreal | News | Comments

There is no effective cure for MS. Read more...

Chemo Before Surgery Benefits Patients with Advanced Ovarian Cancer

May 21, 2015 9:39 am | by Cancer Research UK | News | Comments

550 women with the disease took part in the trial, with 276 given the standard treatment of surgery followed by six cycles of chemotherapy, and 274 had surgery after three cycles of chemotherapy. Read more...

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Actavis Launches New Alzheimer's Disease Therapy

May 21, 2015 9:30 am | News | Comments

The drug was approved by the U.S. Food and Drug Administration (FDA) in December for the treatment of moderate to severe Alzheimer's disease in patients stabilized on memantine hydrochloride and donepezil hydrochloride. Read more...

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Brain Plaque Forecasts Alzheimer’s Years in Advance, Studies Confirm

May 20, 2015 1:49 pm | by Stephanie Guzowski, Editor | News | Comments

Brain plaques may appear up to 30 years prior to developing Alzheimer’s disease, according to the largest analysis to date of beta amyloid in people’s brains. Findings from two new meta-analyses  also confirm that amyloid screening, by PET scan or cerebral spinal fluid test, can help identify the best participants for clinical trials of Alzheimer’s drugs. Read more...

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Lakewood-Amedex: Novel Class Of Antimicrobials Kills Multidrug Resistant-Tuberculosis

May 20, 2015 12:51 pm | News | Comments

Lakewood-Amedex Inc., a leading developer of novel anti-infective pharmaceuticals, announced today that a recent series of in vitro studies conducted by Southern Research in Birmingham, Alabama, have demonstrated that its novel class of antimicrobials, named bisphosphocins, have proven effective at killing multidrug-resistant (MDR) strains.  Read more...

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FDA Approves First and Only Four-Times-A-Year Schizophrenia Treatment

May 20, 2015 12:44 pm | News | Comments

There's a new treatment option for schizophrenia – Invega Trinza (three-month paliperidone palmitate), the first and only schizophrenia medication to be administered just four times a year, providing the longest dosing interval available. Read more...

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Johnson & Johnson Expects Lucrative Return on Drug Pipeline

May 20, 2015 12:35 pm | by Associated Press | News | Comments

Johnson & Johnson expects a lucrative return from its pharmaceutical business, with plans to seek approval by 2019 for more than 10 new products, each with the potential to top $1 billion in annual sales. Read more...

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Activists Want to Void Patents on Gilead's High-Priced Hepatitis C Drug

May 20, 2015 12:15 pm | by Ryan Bushey, Associate Editor | Articles | Comments

These patents are being challenged all over the world. Read more...

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Promising Malaria and Dengue Vaccines Will Not Defeat Diseases

May 20, 2015 8:54 am | by Christopher J. Pace, Ph.D., GlobalData Managing Analyst, Infectious Diseases | Articles | Comments

Some industry pundits rightfully question the modest protective efficacies of CYD-TDV and RTS,S/AS01. Read more...

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