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DDD Update

Daily news and top headlines for drug research professionals

Trial Explores Rivaroxaban in Catheter Ablation

May 15, 2015 1:01 pm | News | Comments

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced results from the VENTURE-AF trial. The study explored the potential of once-daily Xarelto (rivaroxaban) as an alternative to vitamin K antagonists (VKA), used to reduce the risk of blood clots, in people with non-valvular atrial fibrillation (NVAF) undergoing catheter ablation. Read more...

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Tonix Pharmaceuticals Launches Phase 3 Study in Fibromyalgia

May 15, 2015 12:53 pm | News | Comments

Tonix Pharmaceuticals Holding Corp. announced that it has begun a Phase 3 clinical study of TNX-102 SL (cyclobenzaprine HCl sublingual tablet, 2.8 mg) in fibromyalgia, having recently randomized the first patient. The study is expected to enroll approximately 500 patients with fibromyalgia at approximately 35 clinical centers in the U.S. Read more...

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Vitamin D Levels Help Predict Survival of Sick Cats

May 15, 2015 12:48 pm | by Bevin Fletcher, Associate Editor | News | Comments

Vitamin D could give your sickly feline friend its 10th life, according to a recent study. New research from the University of Edinburgh found that higher levels of vitamin D were linked to increased survival changes for hospitalized cats. Read more...

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Early Obesity Research Finds Leptin Hormone May Not Be Overeating Culprit

May 15, 2015 12:42 pm | by University of Cincinnati | News | Comments

For years, scientists have pointed to leptin resistance as a possible cause of obesity. Research led by investigators at the University of Cincinnati (UC) Metabolic Diseases Institute, however, found that leptin action isn't the culprit. Read more...

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Airborne Ebola Threat Analyzed by Scientists

May 15, 2015 12:22 pm | by Seth Augenstein, Digital Reporter | News | Comments

The cross-ocean panic that accompanied the spread of Ebola in Western Africa was fueled by the unthinkable: the worst-case scenario that the dreaded virus could go airborne. No need to worry, according to a team of University of Florida researchers, who have analyzed decades of the virus’s known evolution. Read more...

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U.S. Court Halts Contentious Law on Contact Lens Price-Fixing

May 15, 2015 12:10 pm | by Lindsay Whitehurst - Associated Press | News | Comments

A federal appeals court has halted a new Utah law banning price-fixing for contact lenses that could have wide-ranging implications for the industry amid a fight between manufacturers and discount retailers. Read more...

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PharmaMar Announces New Oncology Advances with Yondelis, PM1183 Compounds

May 15, 2015 9:18 am | News | Comments

The studies were selected for oral discussion session and poster presentation at the American Society of Clinical Oncology's meeting later this month. Read more...

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Findings Should Enhance Treatments for Stopping Immune System Attacks

May 15, 2015 9:12 am | by University of Manchester | News | Comments

Scientists have made an important discovery about an immune cell which is already being used in immunotherapy to treat diseases such as type I diabetes. Read more...

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Scientists Discover Bacterial Cause Behind Fatal Heart Complications

May 15, 2015 9:06 am | by University of Liverpool | News | Comments

Researchers discover a key cause of life threatening heart complications, conditions that frequently follow severe infections with the bacteria responsible for pneumonia and meningitis. Read more...

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Smoking Induces Early Signs of Cancer in Cheek Swabs

May 15, 2015 8:59 am | by University College London | News | Comments

The study provides evidence that smoking induces a general cancer program that is also present in cancers which are not usually associated with it – including breast and gynecological cancers. Read more...

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New Study Eases Fear of Airborne Ebola

May 15, 2015 8:52 am | by University of Florida | News | Comments

At the peak of the Ebola epidemic last fall came a frightening new possibility: a mutation that could allow the disease to spread through the air. Read more...

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Fibromyalgia Treatment Market Value Will Crawl to $1.9B by 2023

May 15, 2015 8:47 am | by Maura Musciacco, MSc, GlobalData's Director or Neurology and Opthalmology | Articles | Comments

The company’s latest report states that while this growth will be primarily driven by the potential introduction of four late-stage pipeline agents. Read more...

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Signaling Pathway Revealed Through Which a Promising Anti-Leukemia Drug Kills Cancer Cells

May 14, 2015 1:01 pm | News | Comments

Inhibiting a protein called BRD4 critical to the survival of acute myeloid leukemia (AML) cells has shown to be an effective therapeutic strategy. However, the mechanism that explains how the protein works has remained a mystery. Now, scientists at Cold Spring Harbor Laboratory (CSHL) have discovered the larger cancer-causing pathway that the protein fits into. Read more...

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ANI Pharmaceuticals Acquires Rights to Testosterone Gel 1%

May 14, 2015 12:50 pm | News | Comments

ANI Pharmaceuticals, Inc. today announced that it has acquired the approved new drug application ("NDA") for a testosterone gel 1% product previously licensed to Teva Pharmaceuticals. Read more...

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AcelRx Awarded Contract to Advance ARX-04

May 14, 2015 12:44 pm | News | Comments

AcelRx Pharmaceuticals, Inc. , a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute pain, today announced it has entered into Contract No. W81XWH-15-C-0046 worth up to $17.0 million, supported by the United States Army Medical Research and Materiel Command (USAMRMC) within the U.S. Department of Defense (DoD). Read more...

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