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Strategies & Technologies Driving Drug Discovery to Market
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Diagnostic Screening for Alzheimer’s Disease: Economics, Policy, and Unanswered Questions

April 28, 2016 10:01 am | by Jillian Godfrey Scaife, Principal, and Nick Simmons-Stern, Consultant, Trinity Partners | Articles | Comments

In recent years, there has been a resurgence in the number of Alzheimer’s disease (AD) clinical trials, led by major efforts from Biogen, Lilly, Genentech/Roche, and others. With the first of these novel AD therapies potentially coming to market as early as 2017/2018, there are a number of critical and as yet unanswered questions surrounding the economics and policy of AD diagnostic screening. 

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Doctors Recommend Prescribing Fewer Opioids after Surgery

April 28, 2016 9:26 am | by Washington University School of Medicine | News | Comments

Bolstering new federal guidelines that advise primary care doctors to carefully weigh the prescribing of opioid painkillers, two experts are recommending that surgeons also consider cutting back on the number of take-home opioid pills prescribed to patients after surgery.

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Tiny Microscopes Reveal Hidden Role of Nervous System Cells

April 28, 2016 9:22 am | by Salk Institute | News | Comments

A microscope about the size of a penny is giving scientists a new window into the everyday activity of cells within the spinal cord. The innovative technology revealed that astrocytes—cells in the nervous system that do not conduct electrical signals and were traditionally viewed as merely supportive—unexpectedly react to intense sensation.

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Who Gets Hooked on Drugs? Genetic Markers Influence Addiction

April 28, 2016 9:16 am | by University of Michigan | News | Comments

Why does one person who tries cocaine get addicted, while another might use it and then leave it alone? Why do some people who kick a drug habit manage to stay clean, while others relapse? 

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Study Reveals COPD Linked to Increased Bacterial Invasion

April 28, 2016 8:36 am | by Vanderbilt University Medical Center | News | Comments

The investigators were interested in the function of the body's mucus membranes like those found in the nose and the lining of the lungs. 

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Advocates Hold NYC Protest Over Price of Pneumonia Vaccine

April 28, 2016 8:31 am | by Rachelle Blinder, Associated Press | News | Comments

About 70 people walked silently and in single file to Pfizer's headquarters, where they placed 2,500 flowers in a crib as though laying tribute on a coffin.

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Molecular Switch to Better Understand Signaling

April 28, 2016 8:30 am | by American Chemical Society | News | Comments

In the alphabets of our genomes, a single typo can mean the difference between health and disease.

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FDA: Yeast Infection Drug Could Cause Miscarriage

April 27, 2016 11:57 am | by Stephanie Guzowski, Editor | News | Comments

The warning came after the release of results of a Danish study that linked oral fluconazole (Diflucan), which treats yeast infections, to miscarriage.

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Oasmia: Positive OS Results From Phase 3 Ovarian Cancer Study

April 27, 2016 10:23 am | News | Comments

Overall Survival data from the Phase 3 study meets endpoint and demonstrates non-inferiority favoring Paclical/Apealea; will form basis for application seeking marketing approval in the United States anticipated for the end of 2016/2017.

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Cholesterol Levels, Not Statins, Influence Colorectal Cancer Risk

April 27, 2016 10:02 am | by University of Pennsylvania | News | Comments

Long-term use of the cholesterol-lowering drugs known as statins does not appear to decrease a patient's risk of colorectal cancer, suggests a new, large case-control study.

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Valeant CEO Will Cite 'Mistakes' in Price-Hiking Strategy

April 27, 2016 9:49 am | by Matthew Perrone, AP Health Writer | News | Comments

J. Michael Pearson will issue the unusual mea culpa on Capitol Hill for the business strategy that made Valeant an industry powerhouse but also triggered a backlash against the Canadian drugmaker.

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MicroRNA Pathway Could Lead to New Avenues for Leukemia Treatment

April 27, 2016 9:28 am | by University of Cincinnati | News | Comments

Cancer researchers have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.

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The New Focus on IL-12 in Oncology Research

April 26, 2016 3:23 pm | by Dr. Premal Thaker M.D., Washington University School of Medicine; Dr. Charles Leath III, M.D., University of Alabama School of Medicine | Articles | Comments

In recent years, researchers have made considerable headway in efforts to improve both the pharmacokinetics and safety of therapies based on rIL-12 based on the use of more advanced delivery mechanisms.

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South Korean Pharmaceutical Market to Experience Slow Four-Year Growth

April 26, 2016 2:00 pm | by Adam Dion, MSc, Senior Industry Analyst, GlobalData | Articles | Comments

Many novel drugs are set to lose their patents by 2020, meaning South Korea’s generics market is expected to increase significantly.

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Could Marijuana Help Treat Painkiller and Heroin Addiction?

April 26, 2016 1:00 pm | by Michael Casey, Associated Press | News | Comments

The growing number of patients who claim marijuana helped them drop their painkiller habit has intrigued lawmakers and emboldened advocates.

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