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DDD Update

Daily news and top headlines for drug research professionals

Scientists’ Structural Discoveries Could Aid in Better Drug Design

August 25, 2015 9:26 am | by The Scripps Research Institute | News | Comments

F. Scott Fitzgerald once said that the test of a first-rate intelligence is the ability to hold two opposed ideas in mind at the same time and still retain the ability to function. Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found the biological equivalent of that idea or something very close. Read more...

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Expression of a Single Gene Lets Scientists Easily Grow Hepatitis C Virus in the Lab

August 25, 2015 9:13 am | by The Rockefeller University | News | Comments

Worldwide, 185 million people have chronic hepatitis C. Since the late 1980s, when scientists discovered the virus that causes the infection, they have struggled to find ways to grow it in human cells in the lab — an essential part of learning how the virus works and developing new effective treatments. Read more...

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Report: Nearly 47 Million People Now Have Dementia

August 25, 2015 8:40 am | by The Associated Press | News | Comments

Health researchers say there are now nearly 47 million people living with dementia globally, up from 35 million in 2009. Read more...

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Protein Plays Important Role in Preventing Pathogen Survival

August 25, 2015 8:15 am | by Helen Knight, MIT News Correspondent | News | Comments

Invading microbial pathogens must scavenge essential nutrients from their host organism in order to survive and replicate. Read more...

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FDA Approves Expanded Use of Novartis' Promacta for Treating Chronic ITP

August 25, 2015 8:00 am | News | Comments

This treatment is intended for children ages 1 and older. Read more...

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Promising Class of New Cancer Drugs Cause Memory Loss in Mice

August 25, 2015 7:45 am | by Rockefeller University | News | Comments

These therapies act on a group of proteins that help regulate the expression of many genes, some of which play a role in cancer. Read more...

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Sierra Leone Releases Its Last Known Ebola Patient

August 25, 2015 7:30 am | by Clarence Roy-Macaulay, Associated Press | News | Comments

Health authorities in Sierra Leone released the country's last known Ebola patient from the hospital on Monday. Read more...

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Genetic Overlapping in Multiple Autoimmune Diseases May Suggest Common Therapies

August 24, 2015 11:39 am | by Children's Hospital of Philadelphia | News | Comments

Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets for treating many of these diseases, in some cases with existing drugs already available for non-autoimmune disorders. Read more...

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New Study Makes Major Advance Toward More Effective, Long-Lasting Flu Vaccine

August 24, 2015 11:06 am | by The Scripps Research Institute | News | Comments

Scientists from The Scripps Research Institute (TSRI) and the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) have found a way to induce antibodies to fight a wide range of influenza subtypes—work that could one day eliminate the need for repeated seasonal flu shots. Read more...

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Scientists Uncover Surprising Mechanism Behind Antibiotic-Resistant Bacteria

August 24, 2015 10:35 am | by The Scripps Research Institute | News | Comments

Every year, more strains of bacteria develop resistance to the antibiotics we use to treat deadly infections. At The Scripps Research Institute (TSRI) scientists have been working to develop new forms of these drugs, including an antibiotic called arylomycin—but tests have shown that it is possible for bacteria to become resistant to arylomycin, too. Read more...

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Second Cancers Are on the Rise; 1 In 5 U.S. Cases Is a Repeat

August 24, 2015 10:08 am | by Marilynn Marchione, AP Medical Writer | News | Comments

Second cancers are on the rise. Nearly 1 in 5 new cases in the U.S. now involves someone who has had the disease before. Read more...

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Powdered Cranberry Combats Colon Cancer in Mice

August 24, 2015 9:58 am | by American Chemical Society | News | Comments

Cranberries are often touted as a way to protect against urinary tract infections, but that may be just the beginning. Researchers fed cranberry extracts to mice with colon cancer and found that the tumors diminished in size and number. Read more...

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A Bridge for Promising Research

August 24, 2015 9:32 am | by Harvard University | News | Comments

A dozen accelerator grants help cover biomedical development gap. Read more...

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Researchers Set to Develop New Diabetes Treatment

August 24, 2015 8:49 am | by University of Otago | News | Comments

The team will use their Proof of Concept Grant to progress their product to commercialization. Read more...

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With Many Ebola Survivors Ailing, Doctors Evaluate Situation

August 24, 2015 8:40 am | by Carley Petesch, Associated Press | News | Comments

Lingering health problems afflicting many of the roughly 13,000 Ebola survivors have galvanized global and local health officials to find out how widespread the ailments are, and how to remedy them. Read more...

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