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DDD Update

Daily news and top headlines for drug research professionals

AstraZeneca's Cancer Drug Gets Positive CHMP Review

October 24, 2014 1:16 pm | News | Comments

AstraZeneca announced that the CHMP of the EMA has adopted a positive opinion recommending the marketing authorisation of Lynparza (olaparib) as monotherapy for the maintenance treatment of adult patients with platinum sensitive relapsed BRCA-mutated (germline and/or somatic) high grade serous epithelial ovarian, fallopian tube or primary peritoneal cancer. Read more...

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Arbor Pharmaceuticals Announces FDA New Drug Approval

October 24, 2014 12:40 pm | News | Comments

Arbor Pharmaceuticals announced that the FDA) has approved its New Drug Application (NDA) for Sotylize (sotalol hydrochloride) oral solution. Read more...                                      

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Baxter Announces FDA Approval For New Hemophilia Drug

October 24, 2014 12:27 pm | News | Comments

Baxter International Inc. announced that the FDA has approved Obizur for the treatment of bleeding episodes in adults with acquired hemophilia A. Read more...                           

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Researchers Find New Target for Treating Childhood Cancers

October 24, 2014 10:31 am | News | Comments

Scientists at the University of Liverpool have uncovered a new target for drugs that could battle a lethal childhood cancer known as neuroblastoma. Read more...                 

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Myriad Establishes New Tumor Research Lab in Europe

October 24, 2014 10:18 am | News | Comments

Myriad Genetics Inc. announced it has established a Tumor BRACAnalysis CDx laboratory in Europe. Read more...                                                        

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Study Finds Best Way to Treat Neck Pain

October 24, 2014 10:03 am | News | Comments

A multicenter study of 169 men and women with a common form of neck pain suggests that both spinal steroid injections and conservative treatment with physical therapy and painkillers work equally well to relieve pain in the short term. Read more...  

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Five More Ebola Vaccines To Be Tested in March

October 24, 2014 9:40 am | by Maria Cheng, AP Medical Writer | News | Comments

The World Health Organization says millions of doses of two experimental Ebola vaccines could be ready in 2015 and five more experimental vaccines will start being tested in March. Read more...           

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New Technique Achieved With Profound Implications for Drug Development

October 24, 2014 9:29 am | News | Comments

A team from The Scripps Research Institute has established a new C-H activation technique that opens the door to creating a broader range of pure molecules of one-handedness or “chirality” by eliminating previous starting-material limitations. Read more...

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After 1st Ebola Case in NYC, 3 Others Quarantined

October 24, 2014 9:06 am | by Jonathan Lemire and Colleen Long - Associated Press | News | Comments

A doctor who became New York City's first Ebola patient was praised for getting treatment immediately upon showing symptoms. Read more...                     

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NIH Announces Grants for Frontotemporal Degeneration Research

October 23, 2014 1:44 pm | News | Comments

The National Institutes of Health will award three large, five-year projects on a specific form of dementia, known as frontotemporal because of the areas of the brain that are affected. Read more...

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Experimental Breast Cancer Drug Has Promise in Combination Therapy

October 23, 2014 1:40 pm | News | Comments

Ewing sarcoma tumors disappeared and did not return in more than 70 percent of mice treated with combination therapy that included drugs from a family of experimental agents developed to fight breast cancer, reported St. Jude Children's Research Hospital scientists.  Read more...

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Shorter TB Treatment Not a Successful Alternative

October 23, 2014 1:27 pm | News | Comments

A clinical drug trial conducted in five Sub-Sahara African countries shows that a shortened (four month) treatment for tuberculosis (TB) is well tolerated and may work well in subsets of TB patients, but overall could not be considered as an alternative to the current six month standard treatment. Read more...

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New Genome Analysis Finds Markers of Aggresive Tumors

October 23, 2014 1:21 pm | News | Comments

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients. Read more...    

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Real-Time Tracking System Developed to Watch Dangerous Bacteria

October 23, 2014 1:02 pm | News | Comments

Combining a PET scanner with a new chemical tracer that selectively tags specific types of bacteria, Johns Hopkins researchers working with mice report they have devised a way to detect and monitor in real time infections. Read more...    

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Pfizer Wins Patent Case in Delaware District Court

October 23, 2014 12:42 pm | News | Comments

Pfizer Inc. announced that the U.S. District Court for the District of Delaware upheld its basic patent and the L-malate salt patent covering Sutent (sunitinib malate) capsules. Read more...           

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