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DDD Update

Daily news and top headlines for drug research professionals

Chemical Disguise Transforms RNAi Drug Delivery

November 19, 2014 1:04 pm | News | Comments

Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery — it is extremely difficult to get RNAi drugs inside the cells in which they are needed.  Read more...

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Light-Responding Blood Vessel Receptor May Be New Target

November 19, 2014 12:46 pm | by Johns Hopkins | News | Comments

A team of researchers from Johns Hopkins Medicine has discovered a receptor on blood vessels that causes the vessel to relax in response to light, making it potentially useful in treating vascular diseases. In addition, researchers discovered a previously unknown mechanism by which blood vessel function is regulated through light of a specific wavelength. Read more...

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Maximizing the Power of Preclinical Cancer Research Tools

November 19, 2014 11:29 am | by Guizhong Liu, Senior Director of Cancer Biology, Crown Bioscience Inc. | Articles | Comments

Drug discovery is a protracted and uncertain process that needs to overcome many hurdles during preclinical and clinical development before it finally achieves regulatory approval for patient treatment. For every drug that reaches the marketplace, well over 100 have been abandoned at some point in their development. Read more...

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Janssen Seeks European Approval of Chronic Inflammatory Disease Drug

November 19, 2014 10:16 am | News | Comments

Janssen submitted an application for European approval regarding a drug intended to treat chronic inflammatory disease of the spine. Read more...                    

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Cardiome Finds Distributor for AFib Drug in South Africa

November 19, 2014 9:59 am | News | Comments

Cardiome entered into a new partnership with Pharmacare Ltd to sell and distribute its AFib drug in South Africa. Read more...                     

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New Laser Therapy Helps Slow Macular Degeneration

November 19, 2014 9:36 am | News | Comments

This new faster laser did not result in damage to the retina. Read more...                               

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Sub-Standard Meds Flood Afghan Market

November 19, 2014 9:24 am | News | Comments

Up to 300 companies in Pakistan produce poor quality drugs exclusively for Afghanistan because their products do not meet Pakistani government standards. Read more...                

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Study Will Test Survivors' Blood to Treat Ebola

November 19, 2014 9:19 am | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

Plasma from survivors contains antibodies, substances the immune system makes to fight the virus. Read more...                         

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New Insight Into Cells Could Lead to Better Drugs

November 19, 2014 9:11 am | News | Comments

Researchers investigated how different types of immune cells communicate with each other – and how they kill cancerous or infected cells. Read more...                   

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Reprogramming Cells, Long Term

November 18, 2014 2:07 pm | by B. D. Colen, Harvard Staff Writer | News | Comments

Harvard Stem Cell Institute (HSCI) researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology (MIT), have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period. Read more...

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Pfizer's Meningococcal Group B Vaccine Is Now Available

November 18, 2014 1:58 pm | News | Comments

Pfizer Inc. announced that Trumenba (Meningococcal Group B Vaccine) is now available for order by healthcare providers in the United States. Read more...

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Anti-Leukemia Drug May Also Work Against Ovarian Cancer

November 18, 2014 1:50 pm | News | Comments

An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine in a study. Read more...

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‘Big Data’ Approach to Help Pinpoint New Stent Drug

November 18, 2014 1:40 pm | by Tracie White, Stanford University | News | Comments

Replacing the current drug used to coat artery-opening stents with a drug more targeted to the actual cause of stent disease could reduce blood clots and heart attacks, researchers say. Read more...

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Strategy: Physicians Prescribe More Generics, Less Brand Name Drugs

November 18, 2014 1:19 pm | News | Comments

Programming electronic health records to make generic drugs the default choice when physicians write prescriptions may offer one way to reduce unnecessary spending and improve health care value in the face of spiraling U.S. health expenditures, according to a new study. Read more...

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Society for Neuroscience Annual Meeting Showcases Strides in Exploring the Brain

November 18, 2014 10:56 am | by Christina Jakubowski, Managing Editor, Bioscience Technology | Articles | Comments

More than 30,000 brain advocates from academia, industry and media converged on Washington, D.C. this week for the 44th annual meeting of the Society for Neuroscience (SfN). Read more...

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