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Daily news and top headlines for drug research professionals

Algorithm Helps Scientists Decipher How Drugs Work Inside the Body

July 24, 2015 12:05 pm | by Columbia University | News | Comments

Researchers at Columbia University Medical Center (CUMC) have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body. The study, published in the journal Cell, could help researchers create drugs that are more efficient and less prone to side effects, suggest ways to regulate a drug’s activity. Read more

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Drug Discovery Spotlight: Mixed Results for Lilly, Biogen Alzheimer’s Drugs; Europe Approves Amgen’s Repatha

July 24, 2015 11:13 am | by Stephanie Guzowski, Editor | News | Comments

This week’s Alzheimer’s Association International Conference (AAIC) in Washington, D.C. delivered highly anticipated data, but not all lived up to the expectation of researchers and investors. Read about this news and more.

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Scientists Discover Why Some Prostate Cancer Tumors are Radiotherapy-Resistant

July 24, 2015 9:25 am | by University of York | News | Comments

The York team have now shown that they are the switch which enables cells to react very rapidly to changes in their environment, such as that provided by cancer treatments. Read more...

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Tracking Breast Cancer Before it Grows

July 24, 2015 9:16 am | by University of Saskatchewan | News | Comments

A team of scientists led by University of Saskatchewan researcher Saroj Kumar is using cutting-edge Canadian Light Source techniques to screen and treat breast cancer at its earliest changes. Read more...

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Zebrafish Reveal Drugs That May Improve Bone Marrow Transplant

July 24, 2015 9:11 am | by Harvard Gazette | News | Comments

The findings could lead to human trials in patients with cancer and blood disorders within a year or two. Read more...

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India's 'Medicine Baba' Gets Drugs from Rich, Gives to Poor

July 24, 2015 9:02 am | by Rishabh R. Jain, Associated Press | News | Comments

Some 40 percent of India's 1.2 billion people have no access to modern medicines because they are too expensive or simply unavailable in government hospitals where supplies are often scarce. Read more...

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EU Drug Regulator Recommends 1st License for Malaria Shot

July 24, 2015 8:54 am | by Maria Cheng, AP Medical Writer | News | Comments

The European Medicines Agency is recommending the world's leading malaria vaccine be licensed even though it is only about 30 percent effective and that protection fades over time. Read more...

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New Antibody Portal Bolsters Biomedical Research Reliability

July 23, 2015 1:35 pm | News | Comments

For years, a crisis has been brewing in molecular biology. The problem is that antibodies - research tools used to identify key proteins at work in a cell - aren't always what they seem. Unreliable antibodies have led to numerous instances of false findings, failed experiments, and wasted money and samples. Read more...

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Positive Clinical Data From Lp(a) Lowering Drug ISIS-APO(a) Rx

July 23, 2015 1:21 pm | News | Comments

Isis Pharmaceuticals, Inc., the leader in RNA-targeted therapeutics, and Akcea Therapeutics announced today that The Lancet has published clinical data evaluating ISIS-APO(a)Rx in healthy volunteers with elevated lipoprotein(a) or Lp(a). Read more...

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Scientists Determine Structure of Important Drug Target Using Groundbreaking Approach

July 23, 2015 1:11 pm | by Van Andel Research Institute | News | Comments

Using the brightest X-ray laser in the world, scientists have determined the structure of a molecular complex that is responsible for regulating vital physiological functions, and that serves as a major pharmacological drug target. Read more...

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Diagnostic Test Developed for Enterovirus D68

July 23, 2015 1:04 pm | by Washington University in St. Louis | News | Comments

Researchers at Washington University School of Medicine in St. Louis have developed a diagnostic test to quickly detect enterovirus D68 (EV-D68), a respiratory virus that caused unusually severe illness in children last year. The outbreak caused infections at an unprecedented rate, with over 1,000 confirmed cases and 14 reported deaths nationwide. Read more...

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Researchers Link HIV Susceptibility to Little-Understood Immune Cell Class

July 23, 2015 12:40 pm | by Stanford University | News | Comments

High levels of diversity among immune cells called natural killer cells may strongly predispose people to infection by HIV, and may be driven by prior viral exposures, according to a new study. Read more...

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Finalists Announced for the 2015 R&D 100 Awards

July 23, 2015 12:26 pm | News | Comments

R&D Magazine today announced the Finalists for the 53rd annual R&D 100 Awards, which honor the 100 most innovative technologies and services of the past year. This year’s Winners will be presented with their honors at the annual black-tie awards dinner on November 13, 2015 at Caesars Palace, Las Vegas, Nevada.

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Modified DNA Building Blocks are Cancer's Achilles Heel

July 23, 2015 8:51 am | by University of Oxford | News | Comments

Cells are thrifty when it comes to synthesizing new DNA. Read more...

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New 'Chemotherapy Booster' Could Treat Lung and Pancreatic Cancer

July 23, 2015 8:42 am | by Institute of Cancer Research | News | Comments

The drug is scheduled to begin first-in-human clinical trials in patients with lung and pancreatic cancers – two cancers with low survival rates that continue to resist currently available treatments. Read more...

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