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DDD Update

Daily news and top headlines for drug research professionals

NIH Announces Grants for Frontotemporal Degeneration Research

October 23, 2014 1:44 pm | News | Comments

The National Institutes of Health will award three large, five-year projects on a specific form of dementia, known as frontotemporal because of the areas of the brain that are affected. Read more...

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Experimental Breast Cancer Drug Has Promise in Combination Therapy

October 23, 2014 1:40 pm | News | Comments

Ewing sarcoma tumors disappeared and did not return in more than 70 percent of mice treated with combination therapy that included drugs from a family of experimental agents developed to fight breast cancer, reported St. Jude Children's Research Hospital scientists.  Read more...

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Shorter TB Treatment Not a Successful Alternative

October 23, 2014 1:27 pm | News | Comments

A clinical drug trial conducted in five Sub-Sahara African countries shows that a shortened (four month) treatment for tuberculosis (TB) is well tolerated and may work well in subsets of TB patients, but overall could not be considered as an alternative to the current six month standard treatment. Read more...

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New Genome Analysis Finds Markers of Aggresive Tumors

October 23, 2014 1:21 pm | News | Comments

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients. Read more...    

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Real-Time Tracking System Developed to Watch Dangerous Bacteria

October 23, 2014 1:02 pm | News | Comments

Combining a PET scanner with a new chemical tracer that selectively tags specific types of bacteria, Johns Hopkins researchers working with mice report they have devised a way to detect and monitor in real time infections. Read more...    

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Pfizer Wins Patent Case in Delaware District Court

October 23, 2014 12:42 pm | News | Comments

Pfizer Inc. announced that the U.S. District Court for the District of Delaware upheld its basic patent and the L-malate salt patent covering Sutent (sunitinib malate) capsules. Read more...           

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New Anti-Cancer Drug Shows Few Side-Effects in Mice

October 23, 2014 10:15 am | News | Comments

A new drug, known as OTS964, can eradicate aggressive human lung cancers transplanted into mice, according to a new report. Read more...                     

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New Study Finds Potential Targets for Personalized Cancer Vaccines

October 23, 2014 10:01 am | News | Comments

A team of University of Notre Dame scientists, in collaboration with researchers at the University of Connecticut, have announced the results of a new study on identifying potential targets for personalized cancer vaccines. Read more...    

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Eli Lilly Adds $375M to Zymeworks Partnership

October 23, 2014 9:52 am | News | Comments

Eli Lilly and Zymeworks said they are expanding a cancer drug development partnership. Read more...                                                   

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Microscopic “Walkers” Find Way Across Cell Surfaces

October 23, 2014 9:47 am | News | Comments

Technology could provide a way to deliver probes or drugs to cell structures without outside guidance. Read more...                                         

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Sutro BioPharma and Celgene Announce New Collaboration Plan

October 23, 2014 9:41 am | News | Comments

Sutro Biopharma announced it has entered into a strategic collaboration and option agreement with Celgene Corporation to discover and develop multispecific antibodies and antibody drug conjugates. Read more...                

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U.S. to Track Everyone Coming from Ebola Nations

October 23, 2014 9:26 am | by Mike Stobbe - AP Medical Writer | News | Comments

All travelers who come into the U.S. from three Ebola-stricken West African nations will now be monitored for three weeks. Read more...                     

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NIH Begins Early Human Clinical Trial of New Ebola Vaccine

October 22, 2014 2:00 pm | News | Comments

Human testing of a second investigational Ebola vaccine candidate is under way at the National Institutes of Health’s Clinical Center in Bethesda, Maryland. Read more...                

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UNC Researchers Found New Characters In Cancer Cells

October 22, 2014 1:47 pm | News | Comments

UNC School of Medicine researchers have pinpointed a set of intriguing characteristics in a previously unknown subpopulation of melanoma cancer cells in blood vessels of tumors. Read more...            

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PhosImmune, PureMHC Working Together on Cancer Immunotherapies

October 22, 2014 1:28 pm | News | Comments

PhosImmune Inc. and PureMHC LLC announced they have entered into a license and collaboration agreement to develop novel antibody-based immunotherapies designed to target cancers. Read more...

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