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DDD Update

Daily news and top headlines for drug research professionals

Affimed’s Lymphoma Drug Shows Favorable Safety Profile, Activity

April 10, 2014 3:15 pm | News | Comments

Affimed Therapeutics AG announced further results from its Phase 1 clinical trial of AFM13 (a bispecific T and Ab antibody) as monotherapy for the treatment of patients with advanced relapsing/refractory (R/R) Hodgkin lymphoma. Read more... 

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Lung Fibrosis and Survival Improved in Preclinical Study of Genkyotex’s GKT137831

April 10, 2014 3:03 pm | News | Comments

Genkyotex, the leading developer of selective NOX enzyme inhibitors, announced the publication of data showing that GKT137831, a first in class NOX1 and 4 inhibitor, was able to reverse lung fibrosis associated with aging in a new model of idiopathic pulmonary fibrosis. Read more...

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BMS Study Shows Potential for New Hep C Treatment

April 10, 2014 2:57 pm | News | Comments

Bristol-Myers Squibb Co. announced Phase 3 results from a global study investigating the all-oral, interferon- and ribavirin-free regimen of daclatasvir and asunaprevir among genotype 1b hepatitis C virus (HCV) infected patients. Read more...   

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Tocagen Reports Positive Trial Results for Brain Cancer Combo

April 10, 2014 2:50 pm | News | Comments

Tocagen Inc. announced updated interim clinical data from two ongoing investigational studies of Toca 511 in combination with Toca FC in 68 patients with recurrent high grade glioma. Read more...                

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Merck’s Hep C Drug Moving to Phase 3

April 10, 2014 2:34 pm | News | Comments

Merck announced additional data from the C-WORTHy study, a Phase 2 trial evaluating a regimen combining MK-5172, an investigational hepatitis C virus NS3/4A protease inhibitor, and MK-8742, an investigational HCV NS5A replication complex inhibitor, among patients with chronic HCV Genotype 1 infection. Read more...

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Breaking News: Drug Ups Survival in H1N1 Mice

April 10, 2014 12:00 pm | News | Comments

A new study reveals that a drug that inhibits a molecule called prostaglandin E2 (PGE2) increases survival rates in mice infected with a lethal dose of the H1N1 flu virus, a finding that paves the way for an urgently needed therapy. Read more...

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Ampio, Paladin Labs Partner on Zertane Rights

April 10, 2014 10:55 am | News | Comments

Ampio Pharmaceuticals Inc. announced that its subsidiary Vyrix Pharmaceuticals has signed an agreement with Paladin Labs Inc. to provide exclusive rights to market, sell and distribute Zertane in Canada, the Republic of South Africa, Sub-Saharan Africa and Latin America. Read more...

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Gilead Posts Positive Results for All-Oral Sofosbuvir Regimens

April 10, 2014 10:47 am | News | Comments

Gilead Sciences Inc. announced data from two Phase 2 studies evaluating investigational all-oral regimens containing the nucleotide analog polymerase inhibitor sofosbuvir (SOF) for the treatment of chronic hepatitis C virus (HCV) infection. Read more...

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AbbVie's New Advanced Parkinson's Treatment Available in Canada

April 10, 2014 10:38 am | News | Comments

AbbVie announced that a new treatment called Duodopa (levodopa/carbidopa intestinal gel) is now available to Canadians with advanced Parkinson's disease. Read more...                        

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Hemophilia Drug Maintains Low Bleeding Rates in Children

April 10, 2014 10:34 am | News | Comments

Biogen Idec and Sobi released positive top-line results of the Kids A-LONG Phase 3 clinical study that evaluated the safety and efficacy of Eloctate in children with severe hemophilia A. Read more...            

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New Vaccine Hope for Viral Cause of Birth Defects

April 10, 2014 10:25 am | News | Comments

Experts in infection and immunity have made a path-finding discovery that could lead to the development of a vaccine for a health-ravaging virus that affects around 50% of adults in the UK. Read more...              

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Have Millions Been Wasted on Flu Drug?

April 10, 2014 10:11 am | News | Comments

British scientists say there isn’t enough evidence to prove the antiviral drug Tamiflu reduces the spread of flu. New study findings question whether governments worldwide were justified in spending millions on the drug during the 2009 swine flu pandemic. Read more...

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Erytech Expands Tumor Starvation Development Portfolio

April 9, 2014 1:59 pm | News | Comments

Erytech Pharma announced the addition of a new product development candidate, ERY-MET, to the company’s tumor starvation product pipeline. Read more...                             

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Lilly, T1D Exchange Collaborate to Advance Diabetes Care

April 9, 2014 1:54 pm | News | Comments

T1D Exchange and Eli Lilly and Co. announced they have entered into a research collaboration that will enable both organizations to gain deeper, real-world insight about the experience of people with type 1 diabetes. Read more...      

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Nektar Reports Positive Preclinical Data for Two Oncology Programs

April 9, 2014 1:48 pm | News | Comments

Nektar Therapeutics announced that positive preclinical data for NKTR-102 and NKTR-214 were presented at the 2014 Annual Meeting of the AACR in San Diego, Calif. Read more...                      

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