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DDD Update

Daily news and top headlines for drug research professionals

Scientists Pinpoint Mutations Responsible for Ineffective 2014-2015 Flu Vaccine

June 25, 2015 12:25 pm | News | Comments

Viruses like influenza have the ability to mutate over time, and given that the flu vaccines administered during the 2014-2015 season were largely ineffective at preventing the spread of the flu, it appears the virus that recently circulated had taken on mutations not accounted for when last year's vaccine was developed. Read more...

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Experimental Treatment Sends Deadly Leukemia Into Remission

June 25, 2015 12:09 pm | by University of Virginia Health System | News | Comments

An experimental new treatment approach for a rare, deadly leukemia can send the disease into remission even in patients for whom the standard therapy has failed, buying them more time to have the stem cell transplant that could save their lives, a small pilot study has found. Read more...

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NIH Begins Clinical Trial of New Medication for Alcohol Use Disorder

June 25, 2015 12:02 pm | by NIH | News | Comments

A clinical trial investigating a potential treatment for alcohol use disorder (AUD) was announced by the National Institute of Alcohol Abuse and Alcoholism (NIAAA). The study will assess the safety and efficacy of gabapentin enacarbil (HORIZANT) in extended-release tablets for treating moderate to severe AUD. NIAAA is part of the National Institutes of Health. Read more...

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NeuroRx: First Human Trial Results Targeting Bipolar Depression, Suicidality

June 25, 2015 11:52 am | News | Comments

NeuroRx, Inc., a clinical phase pharmaceutical company, reports first-in-man efficacy data for a newly-purposed class of drugs targeted towards rapidly reducing symptoms of depression and suicidality in patients with bipolar disorder and maintaining that effect over time. Read more..

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Ebola Cases Not Slowing in Guinea, Sierra Leone

June 25, 2015 9:11 am | by Youssouf Bah, Associated Press | News | Comments

Despite hopes that the deadly Ebola outbreak could soon be contained in West Africa, it shows no signs of abating in Guinea and may be flaring up once more in Sierra Leone as people are flouting rules limiting travel meant to stop it. Read more...

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Research Shows Possible Way to Prevent Degenerative Eye Condition

June 25, 2015 9:07 am | by University of Oxford | News | Comments

Stargardt disease affects around 1 in 10,000 people and begins in childhood, leading to progressive loss of central vision. Read more...

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New Breath Test for Pneumonia

June 25, 2015 8:58 am | by University of Manchester | News | Comments

Researchers from The University of Manchester are part of a team that has identified an important new approach to diagnose infections in critically ill patients rapidly and accurately. Read more...

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Pinpointing the Onset of Metastasis

June 25, 2015 8:55 am | by Lindsay Hock, Editor | News | Comments

Within the oncology community, a debate is raging about two controversial topics. The first is overdiagnosis. According to a recent report in The Wall Street Journal, some leading cancer experts say that zealous screening is finding ever-smaller abnormalities that are being labeled cancer or precancer with little or no justification. Read more...

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EU Approves Daiichi Sankyo's Lixiana

June 25, 2015 8:52 am | News | Comments

The drug is intended for stroke prevention in nonvalvular atrial fibrillation and for the treatment and prevention of reccurent DVT and PE. Read more...

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Future Antibiotics

June 25, 2015 8:45 am | by MIT | News | Comments

The global rise in antibiotic resistance is a growing threat to public health, damaging our ability to fight deadly infections such as tuberculosis. Read more...

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Study Points to Unexplored Realm of Protein Biology, Drug Targets

June 24, 2015 1:07 pm | by The Scripps Research Institute | News | Comments

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins. Read more...

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AbbVie Announces New Phase3b Results for Liver Cirrhosis

June 24, 2015 12:58 pm | News | Comments

AbbVie, a global biopharmaceutical company, today announced TURQUOISE-III study results demonstrating 100 percent (n=60/60) sustained virologic response at 12 weeks post-treatment (SVR12) in genotype 1b (GT1b) chronic hepatitis C virus (HCV) infected adult patients with compensated liver cirrhosis. Read more...

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Researchers ID Best Source of Stem Cells to Block Diabetic Blindness

June 24, 2015 12:52 pm | by UVA | News | Comments

University of Virginia School of Medicine researchers have taken a significant step forward in their efforts to use stem cells to block vision loss caused by diabetic retinopathy, a condition that affects millions of people with diabetes. Read more...

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For Vitiligo Patient, Arthritis Drug Restores Skin Color

June 24, 2015 12:41 pm | by Yale University | News | Comments

A medication for treating rheumatoid arthritis has restored skin color in a patient suffering from vitiligo, according to dermatologists at Yale School of Medicine. The disfiguring condition is best known as the disease that plagued late pop star Michael Jackson. Read more...

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Nanowire Implants Offer Remote-Controlled Drug Delivery

June 24, 2015 12:34 pm | by Seth Augenstein, Digital Reporter | News | Comments

A team of researchers has created a new implantable drug-delivery system using nanowires that can be wirelessly controlled. Read more...

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