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DDD Update

Daily news and top headlines for drug research professionals

New Data on Lilly, Biogen Alzheimer’s Drugs Show Mixed Results

July 22, 2015 1:00 pm | by Stephanie Guzowski, Editor | News | Comments

After much anticipation, new data was released today: Eli Lilly’s experimental drug showed consistently improved results the longer patients took its drug, while Biogen’s yielded stronger efficacy the higher the dose. However, Biogen’s most effective dose, the highest one, had a high rate of a brain-swelling side effect. Read more...

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Four Pharma Firms Create Potential Blockbuster Migraine Drugs

July 22, 2015 11:21 am | by Ryan Bushey, Associate Editor | News | Comments

The market for an effective migraine therapy is worth billions. Read more...

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Diabetes Drug May Protect Against Parkinson's Disease

July 22, 2015 8:54 am | by London School of Hygiene & Tropical Medicine | News | Comments

A type of drug used to treat diabetes may reduce the risk of developing Parkinson’s disease. Read more...

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Gilead: Phase 3 Results for Study Evaluating Switch from TDF-Based Regimens to TAF-Based Regimens

July 22, 2015 8:45 am | News | Comments

The study met its primary endpoint by demonstrating non-inferiority of E/C/F/TAF to the TDF-based regimens at Week 48. Read more...

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U.S., China Will Drive Cancer Companion Diagnostics Market Value to $670M by 2020

July 22, 2015 8:31 am | by Andrew S. Thompson, Ph.D., Senior In Vitro Diagnostics Analyst, GlobalData | Articles | Comments

Other significant drivers of cancer companion diagnostics market growth include increasing disease incidence, accelerating demand for targeted therapies and economic pressures to develop maximally efficient treatments. Read more...

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Horizon Pharma Raises Bid for Depomed to $33 Per Share

July 22, 2015 8:29 am | by The Associated Press | News | Comments

The Dublin-based company said Tuesday that the new offer is contingent on Depomed entering "good faith" talks on the transaction. Read more....

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Untreatable Eczema Beat with Arthritis Drug, Yale Researchers Say

July 22, 2015 8:29 am | by Seth Augenstein, Digital Reporter | News | Comments

An arthritis drug can beat chronic eczema, according to a new study by Yale researchers. Tofacitinib citrate, used for rheumatoid arthritis, led to dramatic improvement in eczema in six patients with moderate to severe forms of the chronic ailment, who had previously tried conventional treatments without improvement, according to the study. Read more...

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Aspirin’s Myriad Effects on Breast Cancer

July 22, 2015 8:20 am | by Cynthia Fox, Science Editor | Articles | Comments

A July Laboratory Investigation report found aspirin may render the environment of cancer stem cells, which can linger post-chemo, hostile to replication. Aspirin may also ward off breast cancer prophylactically, according to the study led by Sushanta Banerjee, Ph.D., research director of the Cancer Research Unit at the Kansas City (Mo.) Veterans Affairs Medical Center. Read more...

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Delcath Receives Orphan Drug Designation To Treat Cholangiocarcinoma

July 21, 2015 1:12 pm | News | Comments

Delcath Systems, Inc., a specialty pharmaceutical and medical device company focused on oncology with an emphasis on the treatment of primary and metastatic liver cancers, announced today that the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has granted Orphan Drug Designation for  melphalan  for the treatment of  cholangiocarcinoma. Read more...

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BMS Gains Breakthrough Therapy Designation for New HIV Treatment

July 21, 2015 1:10 pm | by Ryan Bushey, Associate Editor | News | Comments

The company believes this drug has a considerable edge over other therapies currently on the market. Read more...

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Universal Flu Vaccine in the Works

July 21, 2015 12:52 pm | by American Society for Microbiology | News | Comments

Each year, scientists create an influenza (flu) vaccine that protects against a few specific influenza strains that researchers predict are going to be the most common during that year. Read more...

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FDA Approves Abbott's iDesign System for Vision Treatment

July 21, 2015 12:27 pm | News | Comments

Abbott announced today the U.S. Food and Drug Administration approval and launch of the iDesign Advanced WaveScan Studio System. The system acts as the "brain" of the LASIK procedure, generating a high-definition scan that measures and maps irregularities of the eye that may impact vision. Read more...

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Team Links Gene Expression, Immune System with Cancer Survival Rates

July 21, 2015 12:12 pm | by Krista Conger, Stanford University | News | Comments

Linking gene expression patterns and immune system response to patient survival rates in nearly 18,000 cases of 39 types of cancers illuminates broad prognostic correlations. Read more...

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Studies: Better Sleep May Be Important for Alzheimer's Risk

July 21, 2015 12:01 pm | by Lauren Neergaard, AP Medical writer - Associated Press | News | Comments

To sleep, perchance to... ward off Alzheimer's? New research suggests poor sleep may increase people's risk of Alzheimer's disease, by spurring a brain-clogging gunk that in turn further interrupts shut-eye. Read more...

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Amgen Gains EU Approval for New Cholesterol Lowering Medication

July 21, 2015 8:37 am | News | Comments

The effect of Repatha on cardiovascular morbidity and mortality has not yet been determined. Read more...

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