Advertisement
Strategies & Technologies Driving Drug Discovery to Market
Subscribe to Drug Discovery & Development All
View Sample

FREE Email Newsletter

DDD Update

Daily news and top headlines for drug research professionals

Liberia Seals Slum to Halt Ebola

August 20, 2014 10:09 am | by Jonathan Paye-Layleh, Abbas Dulleh, Associated Press | News | Comments

Security forces blocked off a seaside slum in Liberia's capital Wednesday, stepping up the government's fight to stop the spread of Ebola, unnerving residents and reportedly sparking a protest by disgruntled youths opposed to the quarantine. Read more...

TOPICS:

NIH Launches Three Integrated Precision Medicine Trials

August 19, 2014 4:01 pm | News | Comments

The NIH's Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials (ALCHEMIST) was launched Monday to identify early-stage lung cancer patients with tumors that harbor certain uncommon genetic changes and evaluate whether drug treatments targeted against those changes can lead to improved survival. Read more...

TOPICS:

Amgen's Thyroid Drug Hits Key Phase 3 Endpoints

August 19, 2014 3:52 pm | News | Comments

Amgen announced that a second placebo-controlled Phase 3 study evaluating AMG 416 for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), receiving hemodialysis, met its primary and all secondary endpoints. Read more...

TOPICS:
Advertisement

FDA Accepts NDA for BI’s COPD Combo

August 19, 2014 3:45 pm | News | Comments

Boehringer Ingelheim announced that the FDA accepted for review the New Drug Application (NDA) for the fixed-dose combination (FDC) of tiotropium and olodaterol delivered via the Respimat inhaler. Read more...           

TOPICS:

New Vaccines Can Cut Meningitis Spread by 39%

August 19, 2014 3:35 pm | News | Comments

Investigators have discovered that two new vaccines can prevent the transmission of meningitis bacteria from person to person. The vaccines do this by reducing "carriage" of the responsible bacteria in the nose and throats of the population. Read more...

TOPICS:

DOJ Closes Probe into AstraZeneca Trial

August 19, 2014 3:26 pm | News | Comments

British drugmaker AstraZeneca says the U.S. Department of Justice has closed its investigation into a clinical trial of the company's blood thinner Brilinta, and plans no further action. Read more...               

TOPICS:

Liberian Ebola Patients Receiving ZMapp Improving

August 19, 2014 3:05 pm | by Jonathan Paye-Layleh and John Heilprin | News | Comments

Three Liberian health workers receiving an experimental drug for Ebola are showing signs of recovery, officials said Tuesday, though medical experts caution it is not certain if the drug is effective. Read more...           

TOPICS:

Gamida Cell, Novartis Sign Option Agreement

August 19, 2014 11:56 am | News | Comments

Gamida Cell, a world leader in stem cell expansion technologies and therapeutic products, announced that it has signed an investment and option agreement with Novartis Pharma AG, under which Novartis will invest $35 million in Gamida Cell. Read more...

TOPICS:
Advertisement

DelMar Pharmaceuticals Amends Glioblastoma Trial

August 19, 2014 11:49 am | News | Comments

DelMar Pharmaceuticals Inc. announced a protocol amendment to allow for expanded dosing in its VAL-083 clinical trial had been filed with the U.S. Food and Drug Administration and that a new cohort of a new 50mg/m2 has been opened at three clinical trial sites in the United States. Read more...

TOPICS:

Eisai, Zeria Collaborate on Proton Pump Inhibitor in Japan

August 19, 2014 11:44 am | News | Comments

Eisai Co. Ltd. and Zeria Pharmaceutical Co. Ltd. announced that they have concluded a license agreement concerning E3710, a novel proton pump inhibitor (PPI) discovered and developed in-house by Eisai, which shows promise as a best-in-class treatment. Read more...

TOPICS:

FDA Tentatively Approves Lilly, BI Insulin Glargine

August 19, 2014 11:37 am | News | Comments

The U.S. Food and Drug Administration granted tentative approval for Basaglar (insulin glargine injection), which is indicated to improve glycemic control in adults with type 2 diabetes and in combination with mealtime insulin in adults and pediatric patients with type 1 diabetes. Read more...

TOPICS:

AstraZeneca Posts Positive Antibiotic Combo Results

August 19, 2014 11:30 am | News | Comments

AstraZeneca announced positive top-line results from RECLAIM-1 and RECLAIM-2, the pivotal Phase 3 studies investigating the potential of the antibiotic ceftazidime-avibactam as a treatment for hospitalized adult patients with complicated intra-abdominal infections. Read more...

TOPICS:

Unlocking the Power of Big Data in R&D, Part Two

August 19, 2014 11:23 am | by Sharon Benzeno, PhD, MBA, Senior Director, Business Development Bioinformatics, Elsevier | Articles | Comments

Big data is one of the hottest topics in R&D as its potential to accelerate successful drug development becomes more widely recognized. Part 2 of this two-part article analyses the new data-driven decision-making approaches make a difference to life science R&D. Read more...

TOPICS:

Breaking News: All Missing Ebola Patients Are Back

August 19, 2014 10:16 am | by Jonathan Paye-Layleh, John Heilprin, Associated Press | News | Comments

All the people who were being screened for Ebola when they fled a health center during looting are now back in a hospital, a Liberian official said Tuesda, but it is still not clear where the stolen bloody sheets and mattresses are. Read more...

TOPICS:

Small Molecules, Stem Cells Can Improve Hearing

August 18, 2014 3:14 pm | by Cynthia Fox, Science Editor | Articles | Comments

A scientist has found that a compound, LY-411575, can restore 20% of hearing in deaf mice, or ten decibels. Since electroacoustic hearing aids, at best, improve hearing by five decibels, there is a “good chance” the work will lead to help for deafened patients.

TOPICS:

Pages

X
You may login with either your assigned username or your e-mail address.
The password field is case sensitive.
Loading