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DDD Update

Daily news and top headlines for drug research professionals

Merck Advancing Breast Cancer Drug to Mid-Stage

December 11, 2014 11:33 am | by Linda A. Johnson - AP Business Writer | News | Comments

Merck said it will start mid-stage patient tests of Keytruda in the first half of 2015. Read more...                           

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Patient with Exposure to Ebola to be Admitted at NIH Clinical Center

December 11, 2014 11:30 am | News | Comments

Later today, the National Institutes of Health expects to admit a patient with exposure to the Ebola virus to the NIH Clinical Center’s special clinical studies unit for observation and to enroll in a clinical protocol. The patient is an American nurse who was volunteering services in an Ebola treatment unit in Sierra Leone. Read more...

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Supporting Drug Development Process with Raman Spectroscopy

December 11, 2014 11:25 am | by Kathleen A. Martin, Ph.D., Senior Research Chemist, McCrone Associates, Inc. | Articles | Comments

Raman spectroscopy has steadily gained a wider role in the pharmaceutical industry because of its applicability to several important aspects of drug development and manufacturing. Read more...                         

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Ebola Vaccine Trial Suspended After Side Effects

December 11, 2014 9:17 am | by Associated Press | News | Comments

Swiss researchers have suspended the testing of one of the leading Ebola vaccine candidates after some volunteers reported unexpected side effects. Read more...                                

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‘Placebo Therapy’ Ineffective For Long-Term Chronic Pain Relief

December 11, 2014 9:13 am | News | Comments

Scientists at the University of Liverpool have shown that ‘placebo therapy’ could be effective for short-term pain relief in patients with Complex Regional Pain Syndrome (CRPS), but does not have a lasting impact. Read more...                              

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Actavis Launches Generic Version of Celebrex

December 11, 2014 9:09 am | News | Comments

Actavis plc announced that it has launched a generic version of Celebrex (celecoxib) 50 mg, 100 mg, 200 mg and 400 mg capsules, as part of a settlement agreement with Pfizer, Inc.  Read more...                                   

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Gilead Faces Lawsuit Over Hepatitis C Drug Pricing

December 11, 2014 8:49 am | News | Comments

Gilead has been selling a 12-week treatment of Sovaldi in the United States for approximately $84,000, or $1,000 per pill. Read more...                     

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Targeting Enzyme May Reduce Chemo Drug's Cardiac Side Effects

December 10, 2014 4:56 pm | by Massachusetts General Hospital | News | Comments

MGH investigators identified two compounds that appear to block the cardiac damage caused by the important chemotherapy drug doxorubicin. Their report in the issue of Science Translational Medicine indicates that inhibiting the action of an enzyme that is key to the generation of cellular energy in mitochondria could prevent doxorubicin-induced damage to cardiac cells. Read more...

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New HPV Vaccine Strengthens Cancer Protection

December 10, 2014 4:42 pm | by Associated Press | News | Comments

The drugmaker Merck & Co. Inc. has received approval for an updated version of its Gardasil vaccine that protects against an additional five strains of the virus that causes most cases of cervical cancer. Read more..                  

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Prescribed Painkiller Not Effective in Controlling Back Pain

December 10, 2014 4:35 pm | by University of Rochester | News | Comments

A new study out in the journal Neurology shows that pregabalin is not effective in controlling the pain associated with lumbar spinal stenosis, the most common type of chronic lower back pain in older adults. Read more...

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Ebola Fighters Named Time Person of The Year

December 10, 2014 2:34 pm | by Kiley Armstrong - Associated Press | News | Comments

Time Magazine named doctors, nurses, and others fighting Ebola as 2014's Person of the Year. Read more...                          

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Pinpointing Part of Brain That Triggers Addiction

December 10, 2014 1:14 pm | by University of Michigan | News | Comments

Activating the brain's amygdala, an almond-shaped mass that processes emotions, can create an addictive, intense desire for sugary foods, a new University of Michigan study found. Rewards such as sweet tasty food or even addictive drugs like alcohol or cocaine can be extremely attractive when this brain structure is triggered. Read more...

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Metal Test Could Help Diagnose Breast Cancer Early

December 10, 2014 1:06 pm | by University of Oxford | News | Comments

A team, led by Oxford University scientists, took techniques normally used to analyse trace metal isotopes for studying climate change and planetary formation and applied them to how the human body processes metals. Read more...                                    

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Ohio Lawmakers Debate Execution Drugmaker Bill

December 10, 2014 1:01 pm | by Andrew Welsch-Huggins, AP Legal Affairs Writer - Associated Press | News | Comments

Companies providing Ohio with lethal injection drugs would have their names shielded for at least 20 years, under a bill scheduled for a possible vote that lawmakers say is needed to restart executions in the state. Read more...                                  

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Mylan Launches Generic Versions of Celebrex Capsules

December 10, 2014 12:51 pm | News | Comments

Mylan Inc. announced the U.S. launch of its Celecoxib Capsules, 50 mg, 100 mg, 200 mg, and 400 mg, one of the first available generic versions of Pfizer's Celebrex Capsules, which is indicated for the relief of the signs and symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, and for the management of acute pain in adults. Read more...

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