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Daily news and top headlines for drug research professionals

Phase 2 Efatutazone Trial Shows Challenge of Matching Treatment to Population

April 9, 2014 1:29 pm | News | Comments

Researchers hope that new work on a Phase 2 trial of efatutazone with erlotinib in patients with refractory non-small cell lung cancer will allow them to make better future use of the drug or other drugs in its class. Read more...      


FDA Stops Halozyme PEGPH20 Pancreatic Cancer Trial

April 9, 2014 1:05 pm | News | Comments

Halozyme Therapeutics Inc. announced that the FDA informed the company Tuesday that a clinical hold has been placed on patient enrollment and dosing of PEGPH20 in an ongoing Phase 2 trial evaluating PEGPH20 in patients with pancreatic cancer. Read more...


Faking Fluorescence

April 9, 2014 11:05 am | by Takeharu Nagai, Ph.D., Osaka University, Japan | Articles | Comments

The world’s brightest luminescent protein, a discovery dubbed the “Nano-lantern,” is lighting up the future of in vivo imaging– without the use of external light. This could benefit more advanced applications, such as high-throughput drug screening and single-cell tracking in live animals and plants.


Immunotherapy Shows Early Promise Against Advanced Melanoma

April 9, 2014 10:45 am | News | Comments

A new type of immunotherapy that directs patients’ immune responses toward tumor cell killing, IMCgp100, was well tolerated and showed efficacy in some patients with advanced melanoma in a Phase 1 clinical trial. Read more...        


Glucosamine Promotes Longevity in Mice

April 9, 2014 10:35 am | News | Comments

Feeding glucosamine to mice extended their lifespan by almost 10%, reflecting around eight additional years of human lifespan. Moreover, the supplement improved glucose metabolism in elderly mice, indicating that it may provide protection from diabetes. Read more...


Roche Snags New Biopharma Company for Antibiotics Deal

April 9, 2014 10:20 am | News | Comments

Spero Therapeutics LLC, a biopharmaceutical company founded to develop novel therapies for treatment of bacterial infections, has entered into an antibiotics partnership with Roche. Read more...                


Compound Holds Potential to Treat Drug-Resistant Leukemias

April 9, 2014 10:06 am | News | Comments

Research in mice and human cell lines has identified an experimental compound dubbed TTT-3002 as potentially one of the most potent drugs available to block genetic mutations in cancer cells blamed for some forms of treatment-resistant leukemia.  Read more...


Teva Launches Generic Fish Oil Drug

April 9, 2014 8:30 am | News | Comments

Teva Pharmaceutical Industries said Tuesday it is now selling a generic version of the heart medication Lovaza, which is used to treat high triglyceride levels. Lovaza is made from omega-3 fish oils. Read more...            


Minitron Incubator Shaker

April 8, 2014 4:27 pm | Product Releases | Comments

The Minitron incubator shaker from INFORS HT has the same characteristics as the company’s Multitron incubator shaker, but on a smaller scale.


Update: Arkansas AG Files Petition on Risperdal Ruling

April 8, 2014 1:47 pm | by Andrew DeMillo | News | Comments

Arkansas Attorney General Dustin McDaniel asked the state Supreme Court to reconsider its decision tossing out a $1.2 billion judgment against drugmaker Johnson & Johnson, saying justices did "significant harm" to the state and broke from 170 years of precedent. Read more...


Curis, Debiopharm Report Anti-Tumor Activity, Synergy with Debio 0932

April 8, 2014 1:39 pm | News | Comments

Curis Inc. and Debiopharm Group announced the presentation of data for Debio 0932 at the Annual Meeting of the AACR that demonstrated synergy between Debio 0932 and various standard of care (SOC) agents in multiple in vitro and xenograft models of NSCLC and RCC. Read more...


USPTO Grants Hovione a New Inhaler Patent

April 8, 2014 1:27 pm | News | Comments

Hovione announced that the United States Patent and Trademark Office has granted a patent for a capsule-based, low-cost dry powder inhaler (DPI) to Hovione less than three years after the patent was filed and after just one Office Action– unusual speed for an inhaler application. Read more...


Calithera Glutaminase Inhibition Assay Shows Promise

April 8, 2014 1:17 pm | News | Comments

Calithera Biosciences, a clinical-stage biotechnology company focused on the development of novel cancer therapeutics, announced that data for its lead clinical candidate, CB-839, were featured in two presentations at the 2014 AACR Annual Meeting. Read more...


Pharmacyclics Files Imbruvica Supplemental NDA

April 8, 2014 12:45 pm | News | Comments

Pharmacyclics Inc. announced that it has submitted a sNDA to the FDA based on data from the Phase 3 RESONATE study, a head-to-head comparison of Imbruvica versus ofatumumab in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma. Read more... 


Zohydro Maker Sues to Block Massachusetts Ban

April 8, 2014 12:27 pm | News | Comments

The maker of Zohydro, a controversial new prescription painkiller, has filed a lawsuit in the U.S. District Court on Monday seeking to block Massachusetts' ban on local doctors prescribing and dispensing the drug. Read more...    



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