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DDD Update

Daily news and top headlines for drug research professionals

Protein Complex Offer Fresh Clues About Alzheimer's

November 13, 2014 1:23 pm | by Andrea Crawford, Columbia University | News | Comments

Columbia neurologist Scott Small, MD, was hot on the trail of a relatively unknown cellular component known as retromer and sure he was on to something big—the molecular engine underlying the pathologies at the core of Alzheimer’s devastating symptoms. Read more...

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Online Tool Provides Health Info by ZIP Code, District

November 13, 2014 1:15 pm | News | Comments

For the first time, anyone can easily access comprehensive California health statistics by ZIP code, city and legislative district thanks to a new web tool created by the UCLA Center for Health Policy Research.  Read more...

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Injectable Antidote for Carbon Monoxide Poisoning

November 13, 2014 1:10 pm | News | Comments

When Joseph Roderique was a first-year student in the Virginia Commonwealth University School of Medicine, he had an idea for an injectable antidote for carbon monoxide poisoning. It was a big idea, one that could have dramatic and wide-ranging results if he could make it work. Read more...

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Facets of the Flu

November 13, 2014 12:58 pm | by Elizabeth Cooney, Harvard Medical School | News | Comments

Infectious disease specialist Raphael Dolin, the Maxwell Finland Professor of Medicine at Harvard Medical School and at Beth Israel Deaconess Medical Center discuss flu, vaccination, and the (limited) evidence behind hand washing. Read more...   

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'Smart' Drugs Won't Make Smart People Smarter

November 13, 2014 12:46 pm | News | Comments

It is claimed one in five students have taken the 'smart' drug Modafinil to boost their ability to study and improve their chances of exam success. But new research into the effects of Modafinil has shown that healthy students could find their performance impaired by the drug. Read more...

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Roche Teams Up with LabCentral to Support Biotech Startups

November 13, 2014 12:27 pm | News | Comments

LabCentral and Roche announced an agreement in which Roche would provide technology and financial support to LabCentral, a first-of-its-kind shared laboratory space designed as a launchpad for high-potential life-sciences and biotech startups. Read more...

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When Tobacco Saved Lives

November 13, 2014 10:21 am | by Skip Derra | Articles | Comments

Will ZMapp’s Ebola success force big pharma to take plant-based drugs seriously? Read more...                                                      

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Abivax to Commercialize Vaccines in Asia, Latin America

November 13, 2014 10:05 am | News | Comments

Abivax, a leading European, clinical stage biopharmaceutical company developing and commercializing anti-viral compounds and human vaccines, announced that it has signed an agreement with The Finlay Institute, Havana, Cuba, that will allow it to commercialize vaccines against typhoid, meningococcus, and leptospirosis, in Asian and Latin American markets. Read more...

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AstraZeneca, Isis Pharmaceuticals to Co-Develop Targeted Delivery

November 13, 2014 9:57 am | News | Comments

Isis Pharmaceuticals Inc. and AstraZeneca announced a strategic alliance to discover and develop novel delivery methods for antisense oligonucleotides. The new delivery approaches seek to target the desired tissue more effectively. Read more...                   

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Gene Study Boosts Interest in Heart Drug Zetia

November 13, 2014 9:50 am | by Marilynn Marchione, AP Chief Medical Writer - Associated Press | News | Comments

Scientists have discovered gene mutations that give people naturally lower cholesterol levels and cut their risk of heart disease in half. That discovery may have a big implication. Read more...

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Ebola Drug Testing Sparks Ethics Debate

November 13, 2014 9:36 am | by Matthew Perrone, AP Health Writer - Associated Press | News | Comments

Health officials are scrambling to begin human testing of a handful of experimental drugs for Ebola. But the effort has sparked an ethical debate over how to study unproven medicines amid an outbreak that has killed nearly 5,000. Read more...

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Improved Survival in Women with HER2 Negative Breast Cancer

November 13, 2014 9:22 am | News | Comments

The results from a pooled analysis of two Phase 3 Halaven (eribulin) trials are published in Breast Cancer Research and Treatment. Findings from the pooled analysis show that eribulin improves overall survival in women compared to control. Read more...

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Measuring PD-L1 Expression in CTCs in Lung Cancer Patients

November 12, 2014 2:34 pm | News | Comments

Epic Sciences will present an analysis of PD-L1 protein expression on circulating tumor cells (CTCs) from non-small cell lung cancer (NSCLC) patients.  Read more...                                               

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Next-Gen Melanoma Drug Excels in Lab Tests

November 12, 2014 2:16 pm | by Garth Sundem, University of Colorado | News | Comments

A University of Colorado Cancer Center study published online in the journal Molecular Cancer Therapeutics reports anti-cancer activity in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733, a small molecule inhibitor of MEK1/2.  Read more...

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The Odd Ouster of Sanofi's Former CEO

November 12, 2014 2:16 pm | by Ryan Bushey, Associate Editor | Articles | Comments

This high-flying pharma executive had his career derailed for a variety of surprising factors. Read more...                          

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