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DDD Update

Daily news and top headlines for drug research professionals

Specialty Drug Prescription Service ZappRx Raises $5.6M

April 7, 2015 2:29 pm | by Ryan Bushey, Associate Editor | Articles | Comments

This brings the total funding for the Boston-based startup to 8.8 million. Read more...

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Using Sound Waves to Detect Rare Cancer Cells

April 7, 2015 12:06 pm | by Anne Trafton, MIT | News | Comments

Acoustic device can rapidly isolate circulating tumor cells from patient blood samples. Read more...

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Shire: Clear Regulatory Path Forward for Investigational ADHD Treatment

April 7, 2015 11:54 am | News | Comments

Shire plc announces that it has reached an agreement with the U.S. Food and Drug Administration (FDA) on a clear regulatory path for SHP465 (triple-bead mixed amphetamine salts - MAS), an investigational oral stimulant medication being evaluated as a potential treatment for Attention-Deficit/Hyperactivity Disorder (ADHD) in adults. Read more..

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New R&D Alliance Forms to Find First-Ever Biomarker for Pancreatic Cancer

April 7, 2015 11:49 am | by Ryan Bushey, Associate Editor | Articles | Comments

This program will utilize a precision medicine approach to potentially find a cure for this disease. Read more...

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Prosecutors Seek Congressional Probe of Supplement Industry

April 7, 2015 11:48 am | by Mary Esch - Associated Press | News | Comments

Fourteen attorneys general asked Congress to launch an investigation of the herbal supplements industry and to consider giving the U.S. Food and Drug Administration stronger oversight of the industry, New York Attorney General Eric Schneiderman announced. Read more...

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Study: Breast Cancer Overtreatment Costs U.S. $4B a Year

April 7, 2015 11:44 am | by Ricardo Alonso-Zaldivar, Associated Press Writer | News | Comments

Sharpening a medical debate about the costs and benefits of cancer screening, a new report estimates that the U.S. spends $4 billion a year on unnecessary medical costs due to mammograms that generate false alarms, and on treatment of certain breast tumors unlikely to cause problems. Read more...

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Scientists Identify Receptor for Asthma Associated Virus

April 6, 2015 5:01 pm | by National Institute of Allergy and Infectious Disease | News | Comments

Scientists have identified a cellular receptor for rhinovirus C. Read more...

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Cancer Drug Shows Promise for Treating Stroke

April 6, 2015 4:51 pm | by University of Victoria | News | Comments

Neuroscientists discovered a cancer drug may improve recovery rates for diabetic patients who have suffered a stroke. Read more...

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BMS, uniQure to Collaborate on Developing Gene Therapies for Cardiovascular Diseases

April 6, 2015 4:42 pm | News | Comments

Bristol-Myers Squibb and uniQure N.V. announced an agreement that provides Bristol-Myers Squibb with exclusive access to uniQure’s gene therapy technology platform for multiple targets in cardiovascular diseases. Read more...

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Study Suggests New Role for Gene in Suppressing Cancer

April 6, 2015 4:37 pm | by University of Manchester | News | Comments

Scientists have discovered that a previously known gene also helps cells divide normally and that its absence can cause tumors. Read more...

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Two Compounds Target the Gut to Lower Blood Sugar

April 6, 2015 4:32 pm | by Toronto General Hospital Research Institute | News | Comments

Researchers have discovered metformin and resveratrol trigger novel signaling pathways in the small intestine to lower blood sugar. Read more...

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Cancer Drug Target also Essential for Blood Cell Recovery

April 6, 2015 4:26 pm | by Walter & Eliza Hall Institute of Medical Research | News | Comments

Blocking key survival proteins is a promising tactic for treating cancer, however new research suggests care should be taken as these proteins are also vital for emergency blood cell production. Read more...

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New Developments in Characterizing Protein-Small Molecule Interactions for Drug Discovery

April 6, 2015 4:26 pm | by Bill Sawka, MicroCal Product Manager, Malvern Instruments & Natalia Markova, Principal Scientist – MicroCal, Malvern Instruments | Articles | Comments

Isothermal titration calorimetry (ITC) is a highly valuable technique that is used throughout drug discovery workflow to study the binding interactions of proteins and small molecules. It is an essential tool for both drug design and the study and regulation of protein interactions. Read more...

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Putting Big Data to Work

April 6, 2015 12:33 pm | by Beth Dougherty, Harvard University | News | Comments

What do you get when you mix data from a genome-wide association study of schizophrenia with electronic medical information about blood cancer? Read more...

Emerging Form of Poliovirus Threatens Hope for Eradication

April 6, 2015 12:11 pm | by Erin Digitale, Stanford University | News | Comments

A newly recognized form of poliovirus has emerged from one of the vaccines being used to eradicate the paralyzing illness. Stanford’s Yvonne Maldonado and others are studying how to solve the problem. Read more...

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