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DDD Update

Daily news and top headlines for drug research professionals

Forgotten Smallpox Vials Found in Storage Room

July 9, 2014 1:07 pm | by Mike Stobbe, AP Medical Writer | News | Comments

A government scientist cleaning out an old storage room at a research center near Washington made a startling discovery last week- decades-old vials of smallpox packed away and forgotten in a cardboard box. Read more...          

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HIV Vaccine Research Team Loses $1.38M Grant

July 9, 2014 12:54 pm | by David Pitt | News | Comments

An AIDS research team at Iowa State University will not get the final $1.38 million payment of a National Institutes of Health five-year grant after a team member admitted last year to faking research results. Read more...        

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Cinnamon Could Halt the Progression of Parkinson’s

July 9, 2014 12:49 pm | News | Comments

Neurological scientists have found that using cinnamon, a common food spice and flavoring material, can reverse the biomechanical, cellular and anatomical changes that occur in the brains of mice with Parkinson’s disease (PD). Read more...    

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Sandoz Launches Generic Diovan in the U.S.

July 9, 2014 11:24 am | News | Comments

Sandoz announced the U.S. introduction of an authorized generic version of Diovan (valsartan) tablets for the treatment of high blood pressure (HBP) and will market the authorized generic version of Diovan in the same strengths marketed for the branded version of Diovan. Read more...

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Insys Updates Timing of NDA for Dronabinol Oral Solution

July 9, 2014 11:18 am | News | Comments

Insys Therapeutics Inc. announced the successful completion of a human abuse study for Dronabinol Oral Solution, its proprietary, orally administered liquid formulation of the synthetic cannabinoid dronabinol in development for the treatment of CINV and anorexia associated with weight loss in patients with AIDS. Read more...

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BI Posts Positive Results for Leukemia Drug

July 9, 2014 11:12 am | News | Comments

Results from a Phase 2 study that compared volasertib plus low-dose cytarabine (LDAC), a form of chemotherapy, versus LDAC alone in older patients with untreated acute myeloid leukemia (AML) were published in the American Society of Hematology journal Blood. Read more...

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Actavis Confirms Generic Ampyra Patent Challenge

July 9, 2014 11:06 am | News | Comments

Actavis plc confirmed that it has filed an Abbreviated NDA with the U.S. FDA seeking approval to market Dalfampridine Extended-release Tablets, 10 mg, a generic version of Acorda Therapeutics' Ampyra, which is indicated as a treatment to improve walking in patients with multiple sclerosis. Read more...

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Glioblastoma Cells Disrupt Blood-Brain Barrier

July 9, 2014 10:59 am | News | Comments

Invading glioblastoma cells may hijack cerebral blood vessels during early stages of disease progression and damage the brain’s protective barrier, a study in mice indicates, a finding that may lead to new ways to bring about the death of the tumor, increasing our ability to treat glioblastoma patients. Read more...

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EU Antitrust Fines Drugmakers $580M

July 9, 2014 10:50 am | News | Comments

The European Union's antitrust body is imposing a fine of 428 million euros ($580 million) on France's pharmaceutical company Servier and five producers of generic medicines for distorting competition, by striking a series of deals with the producers of generic medicines to protect Perindopril from price competition. Read more...

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CardioCell Launches Phase 2a Chronic Heart Failure Trial

July 8, 2014 3:19 pm | News | Comments

CardioCell LLC announced the start of its Phase 2a clinical trial for chronic heart failure (HF) patients with non-ischemic cardiomyopathy. Read more...                            

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FDA Approves NovoSeven for Glanzmann's Thrombasthenia

July 8, 2014 3:12 pm | News | Comments

Novo Nordisk announced the FDA approved NovoSeven RT as the first recombinant treatment for bleeding episodes and perioperative management in patients with Glanzmann's Thrombasthenia with refractoriness to platelet transfusions, with or without antibodies to platelets. Read more...

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FDA Grants Priority Review to Purdue’s Abuse-Deterrent Pain Drug

July 8, 2014 3:05 pm | News | Comments

Purdue Pharma L.P. announced that the FDA has granted Priority Review designation for the company’s once-daily, single-entity hydrocodone bitartrate tablet (HYD). Read more...                      

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Nanoparticles Can Enhance Cisplatin in Chemotherapy

July 8, 2014 2:19 pm | News | Comments

Researchers have developed a new formulation of cisplatin, a common chemotherapy drug, that significantly increases the drug's ability to target and destroy cancerous cells. Read more...                   

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Newly Discovered Compounds Could Affect Circadian Rhythm

July 8, 2014 2:08 pm | News | Comments

Scientists have discovered a surprising new role for a pair of compounds that have the potential to alter circadian rhythm. At least one of these compounds could be developed to uncover new therapeutic approaches to a range of disorders. Read more...

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AbbVie Raises Bid for Shire to $51.3B

July 8, 2014 1:51 pm | News | Comments

U.S. drugmaker AbbVie has boosted its offer for Shire by 11 percent to about $51.3 billion, hoping it will be enough to pique the interest of its British counterpart. Read more...                     

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