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Daily news and top headlines for drug research professionals

Mylan Launches One of First Generic Lescol XL Tablets

September 22, 2015 7:30 am | News | Comments

Mylan received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for this product. Read more...

Targeting DNA

September 22, 2015 7:15 am | by Anne Trafton, MIT News Office | News | Comments

MIT biological engineers have developed a modular system of proteins that can detect a particular DNA sequence in a cell and then trigger a specific response. Read more...


Bungling by U.N. Agency Hurt Ebola Response

September 22, 2015 7:00 am | by Maria Cheng, Raphael Satter, and Krista Larson, Associated Press | News | Comments

As a worker at Kenema Government Hospital mixed a batch of chlorine on a broiling August day, he noticed it didn't have its typically strong, bleach-like odor. Concerned, he turned to a consultant with the World Health Organization, who tested the disinfectant and found barely any active ingredient. Read more...


Merck: Phase 3 Studies of Bezlotoxumab to Prevent Clostridium Difficile Infection Recurrence

September 21, 2015 12:34 pm | News | Comments

Merck  today announced that the two pivotal Phase 3 clinical studies for bezlotoxumab, its investigational antitoxin for prevention of Clostridium difficile (C. difficile) infection recurrence, met their primary efficacy endpoint: the reduction in C. difficile recurrence through week 12 compared to placebo, when used in conjunction with standard of care antibiotics for the treatment of C. difficile. Read more...


Gilead: Results from Four Phase 3 Studies Evaluating Hepatitis C Combination

September 21, 2015 12:25 pm | News | Comments

Gilead Sciences, Inc. today announced topline results from four international Phase 3 clinical studies (ASTRAL-1, ASTRAL-2, ASTRAL-3 and ASTRAL-4) evaluating a once-daily, fixed-dose combination of the nucleotide analog polymerase inhibitor sofosbuvir (SOF) with velpatasvir (VEL), an investigational pangenotypic NS5A inhibitor, for the treatment of genotype 1-6 chronic hepatitis C virus (HCV) infection.  Read more...


Clinton To Propose New Prescription Drug Proposal This Week

September 21, 2015 12:20 pm | by Associated Press | News | Comments

Hillary Rodham Clinton says she'll soon roll out a proposal for controlling the cost of prescription drugs, a key fix to President Barack Obama's signature health care law. Read more...


FDA Grants Priority Review for Amgen's Supplemental NDA in Relapsed Multiple Myeloma

September 21, 2015 12:15 pm | News | Comments

Amgen today announced the U.S. Food and Drug Administration (FDA) has accepted for priority review the supplemental New Drug Application (sNDA) of Kyprolis (carfilzomib) for Injection for patients with relapsed multiple myeloma.  Read more...


Vaccine Clears Some Precancerous Cervical Lesions in Clinical Trial

September 21, 2015 12:11 pm | by Johns Hopkins University | News | Comments

Scientists have used a genetically engineered vaccine to successfully eradicate high-grade precancerous cervical lesions in nearly one-half of women who received the vaccine in a clinical trial. The goal, say the scientists, was to find nonsurgical ways to treat precancerous lesions caused by HPV. Read more...


Rare Disease Drug Price Skyrockets, from $13.50 a Tablet to $750

September 21, 2015 11:30 am | by Stephanie Guzowski, Editor | News | Comments

A drug that is the standard of care for treating a life-threatening parasitic infection recently increased in price from $13.50 per pill to $750 — a nearly 5,000 percent jump. Read more...


U.S. Officials to Stop Screening Liberian Passengers for Ebola

September 21, 2015 8:15 am | by Mike Stobbe, AP Medical Writer | News | Comments

Travelers entering the U.S. from Liberia will no longer be screened for Ebola. Read more...


FDA Approves New Indication for Boehringer's Spiriva Respimat

September 21, 2015 8:00 am | News | Comments

It is approved by the FDA for the long-term, once-daily, maintenance treatment of asthma in patients 12 years of age and older. Read more...


Common Drug Presents Fracture Risk to Older Women

September 21, 2015 7:45 am | by University of Queensland | News | Comments

Researchers are urging caution in prescribing one of the world’s most commonly issued drug groups, citing links to increased fracture risks in older Australian women. Read more...


E-Reminders Keep TB Patients on Track with Medication in China

September 21, 2015 7:30 am | by London School of Hygiene & Tropical Medicine | News | Comments

China has world’s second largest number of TB cases, and plans to scale up use of medication monitors in the next five years. Read more... 


Swiss Health Authorities Approve Novartis's Heart Failure Drug

September 21, 2015 7:15 am | News | Comments

Entresto will be available on prescription for adult patients whose condition is classified NYHA class II-IV and with an ejection fraction of 40 percent or less. Read more...


Malaria in Africa Cut by Half Since 2000

September 21, 2015 7:00 am | by University of Oxford | News | Comments

The overall rate of malaria infections in Africa fell by 50 percent between 2000 and 2015. Read more...



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