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DDD Update

Daily news and top headlines for drug research professionals

Uganda Confirms Marburg Fever Killed Man

October 8, 2014 1:22 pm | by Rodney Muhumuza - Associated Press | News | Comments

A Ugandan health worker recently died of Marburg, a highly infectious disease that manifests as a viral hemorrhagic fever, Uganda's Ministry of Health confirmed as health workers moved to quarantine a total of 80 people who had been in contact with the victim. Read more...

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Safety advocates seek stronger warnings on Chantix

October 8, 2014 1:13 pm | by Matthew Perrone - AP Health Writer - Associated Press | News | Comments

Public safety advocates are asking the federal government to strengthen warnings on Pfizer's anti-smoking drug Chantix, even as the drugmaker prepares to argue that a bolded warning about psychiatric problems should be removed from its medicine's label. Read more...

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Cost of Ebola Could Top $32B

October 8, 2014 1:09 pm | by Deb Riechmann | News | Comments

The economic impact of the Ebola epidemic could reach $32.6 billion by the end of next year if the disease ravaging Guinea, Liberia and Sierra Leone spreads to neighboring countries in West Africa, the World Bank Group said. Read more...

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New COPD Inhalation Spray Now Available in U.S. Pharmacies

October 8, 2014 12:58 pm | News | Comments

Boehringer Ingelheim announced that Striverdi Respimat (olodaterol) Inhalation Spray 5 mcg is now available by prescription in pharmacies across the United States. Read more...                               

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Genentech’s Diabetic Retinopathy Drug Gets FDA Priority Review

October 8, 2014 12:47 pm | News | Comments

Genentech, a member of the Roche Group announced that the FDA has accepted to file the company's supplemental sBLA and granted Priority Review of Lucentis (ranibizumab injection) for the treatment of diabetic retinopathy, an eye disease that impacts nearly 7.7 million Americans. Read more...

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Michael J. Fox Foundation Sues New Jersey Facility

October 8, 2014 12:36 pm | News | Comments

Actor Michael J. Fox's foundation is suing a New Jersey research organization, saying a freezer was left open, compromising scientific samples and hurting research efforts it was funding. Read more...

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Past Drug Failures Help Create War on Cancer's Next Successes

October 8, 2014 12:31 pm | News | Comments

The Pharmaceutical Research and Manufacturers of America (PhRMA) released a new report, "Researching Cancer Medicines: Setbacks and Stepping Stones,"  which highlights the number of investigational cancer medicines that did not succeed in clinical trials and how these so-called "failures" are a critical part of the drug development process. Read more...

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1st Ebola Patient Diagnosed in the US Has Died

October 8, 2014 12:14 pm | News | Comments

The first Ebola patient diagnosed in the United States died in a Dallas hospital, according to a hospital spokesman. Read more...                                            

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NIH to Study More Than 200 Rare Diseases

October 8, 2014 12:05 pm | News | Comments

Physician scientists at 22 consortia will collaborate with representatives of 98 patient advocacy groups to advance clinical research and investigate new treatments for patients with rare diseases. Read more...                          

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Drug Cured 16 of 16 Monkeys with Viral Ebola Relative

October 8, 2014 11:31 am | by Cynthia Fox, Science Editor | Articles | Comments

An experimental drug saved the lives of 16 of 16 monkeys with the Marburg virus, a killer near-indistinguishable from Ebola, just as symptoms broke out, said a new study. Read more...                   

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Majority of CROs Exchange TMFs Via Outdated Methods

October 8, 2014 11:05 am | News | Comments

The vast majority of contract research organizations (CROs) surveyed lag clinical trial sponsors in how they exchange trial master file (TMF) documents, according to the Veeva 2014 Paperless TMF Survey: The State of CRO TMFs. Read more...

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C3BS Gets Preferred Access from Mayo Clinic

October 8, 2014 10:58 am | News | Comments

Cardio3 BioSciences (C3BS), a leader in the discovery, development and commercialization of regenerative, protective and reconstructive therapies, announced the signing of a preferred access agreement with Mayo Clinic. Read more...

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'Unsung' Cells Double the Benefits of a New Osteoporosis Drug

October 8, 2014 10:48 am | News | Comments

Experiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder, according to Johns Hopkins researchers. Read more...

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What Kind of Research Can We Trust?

October 8, 2014 10:40 am | News | Comments

Research involving pharmaceutical company input is notoriously compromised. While not all industry ties lead to biased research, and not all biases are a consequence of industry ties, many studies show industry influence can make drugs look safer and more effective than they really are. Read more...

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3 Win Nobel for Super-Zoom Microscopes

October 8, 2014 10:16 am | by Karl Ritter and Malin Rising | News | Comments

Two Americans and a German scientist won the Nobel Prize in chemistry for finding ways to make microscopes more powerful than previously thought possible, allowing scientists to see how diseases develop inside the tiniest cells. Read more...

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