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DDD Update

Daily news and top headlines for drug research professionals

Pfizer Stops China Vaccine Sales as Import License Expires

April 6, 2015 8:16 am | by The Associated Press | News | Comments

The world's second-biggest drugmaker by revenue said that it stopped sales immediately, a decision that affected about 200 of Pfizer's 9,000 employees in China. Read more...

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New Sickle Cell Gene Therapy Approaches

April 2, 2015 11:21 am | by Cynthia Fox, Science Writer | Articles | Comments

As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cell disease, two top scientists are already improving the approach. Read more...

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New Knowledge EphB Signaling May Improve Intestinal Cancers' Treatment

April 2, 2015 10:41 am | by Karolinska Institutet | News | Comments

A new study led by researchers at Sweden's Karolinska Institutet and Nanyang Technological University in Singapore, provides experimental evidence that a drug that inhibits the EphB-signaling pathway in the cell effectively can suppress the development of intestinal tumors. Read more..

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Experimental Ebola Vaccine Appears Safe, Prompts Immune Response

April 2, 2015 10:35 am | by NIH | News | Comments

An early-stage clinical trial of an experimental Ebola vaccine conducted at the National Institutes of Health (NIH) and the Walter Reed Army Institute of Research (WRAIR) found that the vaccine, called VSV-ZEBOV, was safe and elicited robust antibody responses in all 40 of the healthy adults who received it. Read more...

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Teva Pharmaceutical Buys Auspex for $3.2B

April 2, 2015 9:35 am | by The Associated Press | News | Comments

Teva is one of the world's largest generic drug developers. Read more...

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Valeant Pharmaceuticals Completes Salix Acquisition

April 2, 2015 9:30 am | News | Comments

Valeant Pharmaceuticals announced it has completed the previously announced acquisition of Salix Pharmaceuticals. Read more...

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New Evidence for How a Rare Form of Liver Cancer Arises

April 2, 2015 9:25 am | by Anne Trafton, MIT News Office | News | Comments

The research also lays the groundwork for applying this technology to identify other types of DNA damage. Read more...

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Reader Alert: More News, Deep Dives into Industry Trends

April 2, 2015 9:24 am | News | Comments

We’re investing in our valued readers with a creative new approach to delivering editorial content for Drug Discovery & Development that you can use in your daily work and life. It’s a bold, new approach as our staff editors, expert contributors and real-time reporters gather information on critical issues—and offer in-depth reports and track the pulse of your industry. It’s our commitment to our Science and Technology audience.

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Novartis Announces FDA Approval for Iron Chelation Tablets

April 2, 2015 9:18 am | News | Comments

Jadenu is the only once-daily oral iron chelator that can be swallowed whole. Read more...

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Liberia, Sierra Leone Gain in Ebola Crisis; Guinea Struggles

April 2, 2015 9:11 am | by Sarah Dilorenzo, Associated Press | News | Comments

The West African countries of Sierra Leone and Liberia both appear to be on steady paths to ending the epidemic. Read more...

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Making Adjustments After a Packaging Test Failure

April 2, 2015 9:01 am | by Ralph Nigro, Packaging Development Project Specialist, West Pharmaceutical Services, Inc. | Articles | Comments

Every day packages pour into offices and homes. Yet, thoughts about the integrity of that package are rare, unless there is a glaring hole or tear in the primary packaging. When dealing with medical packaging, however, failures are serious business and may compromise patient safety. Read more...

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GeoVax HIV Vaccine Moves Forward

April 1, 2015 1:40 pm | News | Comments

GeoVax Labs, a biotechnology company developing human vaccines for Ebola and HIV, today announced that the HIV Vaccine Trials Network (HVTN) has assigned a trial number, HVTN 114, to the next clinical trial of its clade B preventive HIV vaccine candidate. Read more...

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Pharmacist Group Says Members Shouldn't Aid in Executions

April 1, 2015 1:34 pm | by Julie Watson, The Associated Press | News | Comments

In a move that could heighten the hurdles faced by states attempting to execute prisoners, a leading association for U.S. pharmacists has officially discouraged its members from providing drugs for use in lethal injections. Read more...

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Drilling Down to Genetic Root of Prostate Tumor Development

April 1, 2015 1:26 pm | by Cancer Research UK | News | Comments

Scientists have revealed the root of prostate cancers in individual men, discovering that despite huge genetic variety between tumours they also share common gene faults - insight that could offer new treatment hopes, according to research published in Nature today. Read more..

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Old Cancer Drug Could Have New Use in Fighting Cancer

April 1, 2015 1:15 pm | by University of Missouri | News | Comments

A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients with leukemia. Read more...

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