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DDD Update

Daily news and top headlines for drug research professionals

'Unsung' Cells Double the Benefits of a New Osteoporosis Drug

October 8, 2014 10:48 am | News | Comments

Experiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder, according to Johns Hopkins researchers. Read more...

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What Kind of Research Can We Trust?

October 8, 2014 10:40 am | News | Comments

Research involving pharmaceutical company input is notoriously compromised. While not all industry ties lead to biased research, and not all biases are a consequence of industry ties, many studies show industry influence can make drugs look safer and more effective than they really are. Read more...

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3 Win Nobel for Super-Zoom Microscopes

October 8, 2014 10:16 am | by Karl Ritter and Malin Rising | News | Comments

Two Americans and a German scientist won the Nobel Prize in chemistry for finding ways to make microscopes more powerful than previously thought possible, allowing scientists to see how diseases develop inside the tiniest cells. Read more...

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A Universal Ebola Drug Target

October 8, 2014 10:05 am | News | Comments

University of Utah biochemists have reported a new drug discovery tool against the Ebola virus. According to a study published in the online edition of Protein Science, they have produced a molecule, known as a peptide mimic, that displays a functionally critical region of the virus that is universally conserved in all known species of Ebola. Read more...

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Green Tea-based ‘Missiles’ May Kill Cancer Cells

October 7, 2014 3:31 pm | News | Comments

Green tea has long been known for its anti-oxidant, anti-cancer, anti-aging and anti-microbial properties. A group of researchers from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR has taken the health benefits of green tea to the next level by using one of its ingredients to develop a drug delivery system, which kills cancer cells more efficiently. Read more...

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Manzo Pharmaceuticals' Probiotic Will Not Need FDA Approval

October 7, 2014 3:05 pm | News | Comments

Manzo Pharmaceuticals Inc. announced that after discussions with the FDA, it has been determined that its long lasting lactose digestive aid, Lacto-Freedom, will not need FDA approval to be released to the public. Read more...           

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BMS Won't Pursue FDA Approval for HCV Treatment

October 7, 2014 2:56 pm | News | Comments

Given the rapidly evolving hepatitis C (HCV) treatment landscape in the U.S., Bristol-Myers Squibb has decided that it will not pursue U.S. Food and Drug Administration (FDA) approval of the dual regimen of daclatasvir and asunaprevir for the treatment of HCV genotype 1b patients in the United States and has therefore withdrawn its new drug application (NDA) for asunaprevir. Read more...

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FDA Grants Fast Track Designation to NurOwn for the Treatment of ALS

October 7, 2014 2:45 pm | News | Comments

BrainStorm Cell Therapeutics Inc., a leading developer of adult stem cell technologies for neurodegenerative diseases, announced that the United States Food and Drug Administration (FDA) has designated NurOwn as a Fast Track product for the treatment of amyotrophic lateral sclerosis (ALS, or Lou Gehrig's Disease). Read more...

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A New Pathway Discovered Regulating Autoimmune Diseases

October 7, 2014 2:32 pm | News | Comments

The main function of the immune system is to protect against diseases and infections. For unknown reasons our immune system attacks healthy cells, tissues and organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis. There are currently no existing cures for these diseases. Read more...

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Vivolux Cancer Drug Receives FDA Clearance for Clinical Study

October 7, 2014 2:21 pm | News | Comments

Vivolux, a pharmaceutical company specialized in cancer treatment, announced that the FDA has granted clearance to proceed with VLX1570 to clinical phase 1/2 for treatment against relapsed and/or refractory multiple myeloma. Read more...        

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Experimental Drug Provided to Dallas Ebola Patient

October 7, 2014 10:57 am | by Matthew Perrone, AP Health Writer | News | Comments

A North Carolina drugmaker is providing its experimental antiviral drug to a Dallas patient being treated for Ebola, an emergency step authorized by the Food and Drug Administration. Read more...                                    

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Acacia Pharma Gets Positive Results for PONV Treatment

October 7, 2014 10:36 am | News | Comments

 Acacia Pharma announces positive Phase 3 results with APD421 for the management of post-operative nausea & vomiting (PONV). Read more...                                   

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Stratophase Announces Results From Collaboration with GSK

October 7, 2014 10:21 am | News | Comments

Stratophase, a world-leading provider of automated feeding systems for the biomanufacturing industry, announced the availability of data from a collaboration with the Biopharm Process Research Group at the GSK Medicine Research Centre, applying the Ranger system for Automated Closed Loop Feeding Control (AFC) to a CHO cell culture. Read more...

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Researchers Develop Personalized Ovarian Cancer Vaccines

October 7, 2014 10:02 am | News | Comments

Researchers at the University of Connecticut have found a new way to identify protein mutations in cancer cells. The novel method is being used to develop personalized vaccines to treat patients with ovarian cancer. Read more...         

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Spain Quarantines Three More After Nurse Gets Ebola

October 7, 2014 9:48 am | by Ciaran Giles and Mike Stobbe | News | Comments

Three more people were placed under quarantine for Ebola at a Madrid hospital where a Spanish nurse became infected, authorities said. More than 50 other possible contacts were being monitored. Read more...

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