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DDD Update

Daily news and top headlines for drug research professionals

Genetics of Children's Brain Tumor Unlocked

May 19, 2010 6:12 am | News | Comments

Clinicians and scientists have conducted the most comprehensive analysis to date of pediatric high-grade glioma, making a detailed scan of the genome of 78 newly-diagnosed patients.


Oncolytic Viruses Show Anti-Tumor Activity in Humans

May 19, 2010 6:04 am | News | Comments

Researchers at the University of Helsinki and Oncos Therapeutics published results that demonstrate the anti-tumor immunity of oncolytic viruses in humans, indicating strong efficacy of the viruses against solid tumor cancers.


Viagra Linked to Hearing Loss

May 19, 2010 5:51 am | News | Comments

Research by a University of Alabama at Birmingham professor shows an association between hearing loss and the use of the erectile dysfunction drug Viagra.


FDA Issues Complete Response Letter for Daxas

May 19, 2010 5:47 am | News | Comments

Nycomed and Forest Laboratories, Inc. announced that the U.S. Food and Drug Administration issued a complete response letter regarding the New Drug Application for Daxas.


Abbott Receives BLA for Chagas Test

May 19, 2010 5:39 am | News | Comments

Abbott has received Biologic License Application approval from the United States Food and Drug Administration for the ABBOTT PRISM Chagas test.


Pfizer to Cut 6,000 More Jobs

May 19, 2010 5:27 am | News | Comments

Pfizer Inc. said it will cut 6,000 jobs as it trims manufacturing capacity for health care products worldwide after acquiring smaller rival Wyeth last year.


$250M In Punitive Damages in Novartis Case

May 19, 2010 5:22 am | by Larry Neumeister | News | Comments

A jury that found drug company Novartis discriminated against women by paying them less than men, promoting fewer of them and allowing a hostile workplace awarded $250 million in punitive damages.


Tuberculosis Control Efforts Unsuccessful

May 19, 2010 5:15 am | by Maria Cheng | News | Comments

Global efforts to control tuberculosis have failed and radical new approaches are needed say experts. With more than 9 million people infected last year, including 2 million deaths, officials say there is more tuberculosis now than at any other time in history.


FDA Sends St. Jude Warning Letter

May 19, 2010 5:10 am | by Matthew Perrone | News | Comments

The Food and Drug Administration issued a warning letter to medical device maker St. Jude Medical Inc. for promoting its device for an unapproved use.


Building a Better Assay

May 18, 2010 12:56 pm | by Dahai Dong, Senior Scientist; Mike Koleto, Senior Scientist; Rohan A. Thakur, Associate Director; Richard LeLacheur, Vice President; Christopher Kemper, Business Director, Taylor Technology Inc., Princeton, N.J. | Articles | Comments

A CRO demonstrates a new approach for an equilibrium protein binding LC-MS/MS assay.


Data Snapshot

May 18, 2010 12:06 pm | by Vladimir Brusic, Director of Bioinformatics Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, Mass.; Xiaohong Cao, Senior Scientist, Genzyme Corporation Framingham, Mass. | Articles | Comments

Visual analytics provides insight into cancer vaccine clinical trials.


The Synthetic Side of Protein Expression

May 18, 2010 11:51 am | by Mike May, PhD, Contributing Editor | Articles | Comments

Made-to-order genes fill different research needs.


Enrich, Preserve, and Screen Low-Level Biomarkers

May 18, 2010 11:33 am | by Scott A. Kuzdzal, PhD, Life Sciences Business Leader, Shimadzu Scientific Instruments, Columbia, Md. | Articles | Comments

Biomarkers for early disease detection and therapeutic development are in high demand. However, the discovery process is hindered by several complex challenges.


The Search for Animal Alternatives

May 18, 2010 10:57 am | by Alan Dove, Contributing Editor | Articles | Comments

New assays based on nanotechnology and stem cell science promise to reduce the need for laboratory animals while increasing the success rate of new leads.


Unlocking hESC Success

May 18, 2010 10:00 am | by Ted Agres, Contributing Editor | Articles | Comments

Industry-Academia collaborations may pay off with hESC-based drug screening advances.



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