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DDD Update

Daily news and top headlines for drug research professionals

Genetics of Children's Brain Tumor Unlocked

May 19, 2010 6:12 am | News | Comments

Clinicians and scientists have conducted the most comprehensive analysis to date of pediatric high-grade glioma, making a detailed scan of the genome of 78 newly-diagnosed patients.

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Oncolytic Viruses Show Anti-Tumor Activity in Humans

May 19, 2010 6:04 am | News | Comments

Researchers at the University of Helsinki and Oncos Therapeutics published results that demonstrate the anti-tumor immunity of oncolytic viruses in humans, indicating strong efficacy of the viruses against solid tumor cancers.

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Viagra Linked to Hearing Loss

May 19, 2010 5:51 am | News | Comments

Research by a University of Alabama at Birmingham professor shows an association between hearing loss and the use of the erectile dysfunction drug Viagra.

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FDA Issues Complete Response Letter for Daxas

May 19, 2010 5:47 am | News | Comments

Nycomed and Forest Laboratories, Inc. announced that the U.S. Food and Drug Administration issued a complete response letter regarding the New Drug Application for Daxas.

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Abbott Receives BLA for Chagas Test

May 19, 2010 5:39 am | News | Comments

Abbott has received Biologic License Application approval from the United States Food and Drug Administration for the ABBOTT PRISM Chagas test.

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Pfizer to Cut 6,000 More Jobs

May 19, 2010 5:27 am | News | Comments

Pfizer Inc. said it will cut 6,000 jobs as it trims manufacturing capacity for health care products worldwide after acquiring smaller rival Wyeth last year.

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$250M In Punitive Damages in Novartis Case

May 19, 2010 5:22 am | by Larry Neumeister | News | Comments

A jury that found drug company Novartis discriminated against women by paying them less than men, promoting fewer of them and allowing a hostile workplace awarded $250 million in punitive damages.

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Tuberculosis Control Efforts Unsuccessful

May 19, 2010 5:15 am | by Maria Cheng | News | Comments

Global efforts to control tuberculosis have failed and radical new approaches are needed say experts. With more than 9 million people infected last year, including 2 million deaths, officials say there is more tuberculosis now than at any other time in history.

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FDA Sends St. Jude Warning Letter

May 19, 2010 5:10 am | by Matthew Perrone | News | Comments

The Food and Drug Administration issued a warning letter to medical device maker St. Jude Medical Inc. for promoting its device for an unapproved use.

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Building a Better Assay

May 18, 2010 12:56 pm | by Dahai Dong, Senior Scientist; Mike Koleto, Senior Scientist; Rohan A. Thakur, Associate Director; Richard LeLacheur, Vice President; Christopher Kemper, Business Director, Taylor Technology Inc., Princeton, N.J. | Articles | Comments

A CRO demonstrates a new approach for an equilibrium protein binding LC-MS/MS assay.

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Data Snapshot

May 18, 2010 12:06 pm | by Vladimir Brusic, Director of Bioinformatics Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, Mass.; Xiaohong Cao, Senior Scientist, Genzyme Corporation Framingham, Mass. | Articles | Comments

Visual analytics provides insight into cancer vaccine clinical trials.

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The Synthetic Side of Protein Expression

May 18, 2010 11:51 am | by Mike May, PhD, Contributing Editor | Articles | Comments

Made-to-order genes fill different research needs.

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Enrich, Preserve, and Screen Low-Level Biomarkers

May 18, 2010 11:33 am | by Scott A. Kuzdzal, PhD, Life Sciences Business Leader, Shimadzu Scientific Instruments, Columbia, Md. | Articles | Comments

Biomarkers for early disease detection and therapeutic development are in high demand. However, the discovery process is hindered by several complex challenges.

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The Search for Animal Alternatives

May 18, 2010 10:57 am | by Alan Dove, Contributing Editor | Articles | Comments

New assays based on nanotechnology and stem cell science promise to reduce the need for laboratory animals while increasing the success rate of new leads.

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Unlocking hESC Success

May 18, 2010 10:00 am | by Ted Agres, Contributing Editor | Articles | Comments

Industry-Academia collaborations may pay off with hESC-based drug screening advances.

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