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DDD Update

Daily news and top headlines for drug research professionals

A Different Culture

August 1, 2011 10:55 am | by Bill Cooney, President and CEO; MedPoint Digital, Evanston, Ill. | Articles | Comments

Over the last decade, research programs have expanded offshore into Eastern Europe, Latin America, and Asia-Pacific. This has been driven in large part by escalating costs and difficulties associated with patient recruitment in North America and Western Europe.


A Holistic Approach

August 1, 2011 10:39 am | by Ken Stuart, PhD, President and Founder; Seattle BioMed, Seattle | Articles | Comments

Dramatic increases in the ability to measure biomolecules and biological traits, as well as increased capacity for computers to store and analyze this data, mean that it is now possible to understand diseases at the level of biological complexity at which they occur.


The Human Element in Toxicity Testing

August 1, 2011 10:27 am | by Vanessa Ott, Hepatocytes Product Manager; Blake Anson, Cardiomyocytes Product Manager; Cellular Dynamics International, Madison, Wisc. | Articles | Comments

Current in vitro cell models—such as animal cells, tumor cell lines, and cadaveric tissue—do not truly reflect human biology and have significant limitations in reproducibility and/or availability.


Baxter Ventures to Invest in Early-Stage Therapies

August 1, 2011 9:52 am | News | Comments

Baxter International Inc. has established Baxter Ventures to invest up to $200 million in equity in promising early-stage companies developing therapies that complement Baxter's existing portfolio.


SETTLE Study Completes Enrollment

August 1, 2011 9:49 am | News | Comments

Merck KGaA announced that a Phase 3 trial designed to evaluate the efficacy and safety of a dose range of safinamide as an adjunctive therapy to a stable dose of levodopa has completed patient enrollment.


Eli Lilly India, Lupin Collaborate on Diabetes Drugs

August 1, 2011 9:45 am | News | Comments

Eli Lilly India and Lupin Limited announced a collaboration to promote and distribute Lilly's Huminsulin range of products.


Switching Off Serotonin-producing Neurons

August 1, 2011 9:43 am | by David Cameron | News | Comments

Researchers have developed a way to turn off targeted cell populations while leaving others unaffected. The group focused on serotonin-producing neurons, observing how mice behave in a normal environment when suddenly their serotonin neurons are turned down.


Researchers Find Key to Oncogene Addiction

August 1, 2011 9:38 am | News | Comments

A team of scientists has laid bare the mechanism behind a phenomenon called oncogene addiction in mice suffering from a form of leukemia that mimics acute myelogenous leukemia in humans.


Grant Funds Fasudil Research for Parkinson's Disease

August 1, 2011 9:36 am | News | Comments

Researchers are investigating Fasudil,a drug that has the potential to not only alleviate Parkinson’s symptoms, but also to halt the disease’s progression.


Analyst upgrades Eli Lilly to 'Market Perform'

August 1, 2011 9:28 am | News | Comments

Drugmaker Eli Lilly and Co. has several growth drivers that will help balance an upcoming wave of patent expirations for key products and keep its dividend sustainable, according to a Leerink Swann analyst.


Identifying Previously Undetected Proteins

August 1, 2011 9:27 am | by Jeff D. Chapman, PhD, Director, Discovery Products Business Center; Jean-Marc Busnel, PhD, Senior Applications Scientist; Beckman Coulter, Inc., Brea, Calif. | Articles | Comments

Liquid chromatography-electrospray ionization-mass spectrometry is commonly used to identify proteins from complex peptide mixtures made from enzymatic digests of selected proteomes. However, these experiments only represent part of the proteome.


Western Blotting Kits

August 1, 2011 7:23 am | Drug Discovery & Development | Product Releases | Comments

AMRESCO has introduced two Rapid Western Blotting Kits that are compatible with goat and rat primary antibodies. Rapid Western Blotting Kits reduce the time from transfer to protein detection to less than 90 minutes.


Biological Safety Cabinet

August 1, 2011 7:12 am | Product Releases | Comments

NuAire has updated its LabGard ES model NU-629 Animal Handling Class II, Type A2 Biological Safety Cabinet. The NU-629 provides personnel, product, and environmental protection for sensitive animal handling and cage changing procedures.


Accelrys Collaborating with ACD/Labs

August 1, 2011 7:03 am | News | Comments

Accelrys, Inc. announced that it is continuing a partnership with ACD/Labs and deploying ACD/Labs analytical component collection on the Accelrys Pipeline Pilot enterprise R&D platform.


Pozen Losses Hit $6.4M for Quarter

August 1, 2011 6:33 am | News | Comments

Drug developer Pozen Inc. said that it lost money in the second quarter on lower payments from its arthritis drug Vimovo. Pozen reported a loss of $6.4 million, or 21 cents per share.



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