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DDD Update

Daily news and top headlines for drug research professionals

More Salt Could Mean Less Stress

April 6, 2011 7:40 am | News | Comments

All those salty snacks available at the local tavern might be doing more than increasing your thirst: They could also play a role in suppressing social anxiety.

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BMS Releases HCV Trial Results

April 6, 2011 7:37 am | News | Comments

PEG-Interferon lambda and ribavirin achieved higher rates of rapid virologic response in genotypes 1, 2, 3, and 4 than the standard regimen of PEG-Interferon alfa and ribavirin in treatment-naïve patients chronically infected with hepatitis C.

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C3BS Presents Stem Cell Trial Data

April 6, 2011 7:30 am | News | Comments

Belgian biotechnology company, Cardio3 BioSciences, presented detailed data from the Phase 2 clinical trial of C3BS-CQR-1 (C-Cure), its novel stem cell therapy for ischemic cardiomyopathy.

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Interferon-fused Antibody Increases Tumor Retention

April 6, 2011 7:24 am | News | Comments

Immunomedics, Inc. announced results from a preclinical study of C2-2b-2b, a new protein construct created by the company's dock-and-lock method for protein engineering. C2-2b-2b is an immunocytokine that targets the HLA-DR antigen.

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Data Shows OGX-427 Inhibits Hsp27

April 6, 2011 7:15 am | News | Comments

OncoGenex Pharmaceuticals, Inc. announced that preclinical data utilizing their pipeline compound OGX-427 demonstrated the ability of the drug candidate to inhibit Heat Shock Protein 27.

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Researchers Develop Screen for Anticancer Drug Targets

April 6, 2011 7:09 am | News | Comments

Tumor suppressor genes normally control the growth of cells, but cancer can spring up when these genes are silenced by certain chemical reactions that modify chromosomes.

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Nanopolymer May Reduce Chemo Side Effects

April 6, 2011 7:06 am | News | Comments

A biochemist has developed a nanopolymer that can be coated with drugs, enter cells and then be removed to determine which proteins in the cells the drug has entered, which may help reduce drug side effects.

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Strawberries May Help Prevent Esophageal Cancer

April 6, 2011 6:55 am | News | Comments

Eating strawberries may be a way to help people at risk of esophageal cancer protect themselves from the disease, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center.

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Valeant Proposes New Cephalon Board

April 6, 2011 6:50 am | News | Comments

Valeant Pharmaceuticals named its own slate of directors for Cephalon as part of its hostile takeover bid. Cephalon Inc. recently rejected an unsolicited, $5.7 billion offer from Canada's Valeant.

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Prochieve Cuts Preterm Births in Half

April 6, 2011 6:45 am | by Lauran Neergaard | News | Comments

A simple treatment - a hormone-containing vaginal gel - significantly reduces premature births among pregnant women who are at high risk because of a problem with the cervix, government researchers reported.

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Detecting Multiple miRNA Markers with Microarrays

April 5, 2011 10:40 am | by John Keefe, Sr. Product Manager-RNA; Affymetrix, Santa Clara, Calif. | Articles | Comments

Small non-coding RNA has become a very important class of molecules for understanding cellular development, differentiation, and the mechanisms of disease for genetic disorders such as cancer.

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Small RNA Discovery and Profiling with Next-Generation Sequencing

April 5, 2011 10:32 am | Articles | Comments

As next-generation sequencing continues to evolve as a research tool, it is being adopted for examining gene regulation at the transcriptional and post-transcriptional levels.

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Antibody Purification

April 5, 2011 8:16 am | Drug Discovery & Development | Product Releases | Comments

GE Healthcare’s rProtein A GraviTrap, Protein G GraviTrap and rProtein A/Protein G GraviTrap, gravity-flow columns enable single-step, efficient manual purification of monoclonal and polyclonal antibodies from various species in milligram scale.

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Thermal Cycler

April 5, 2011 8:12 am | Drug Discovery & Development | Product Releases | Comments

Agilent Technologies, Inc. introduced the SureCycler 8800, a full-featured thermal cycler that eliminates the need to choose between popular features of other major PCR instruments.

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Critical And PolyTherics Working on Delivery System

April 5, 2011 8:03 am | News | Comments

Critical Pharmaceuticals and PolyTherics Limited announced a collaboration to develop a novel injectable sustained release drug delivery system for a high value biological drug.

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