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DDD Update

Daily news and top headlines for drug research professionals

NIH Gives $10M for Microneedle Study

November 17, 2010 7:09 am | News | Comments

The National Institutes of Health has awarded $10 million to three groups to advance a technology for the painless, self-administration of flu vaccine using patches containing tiny microneedles that dissolve into the skin.

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Walmart Drug Plan May Not Be Best Option

November 17, 2010 6:46 am | by Ricardo Alonso-Zaldivar | News | Comments

A new Medicare drug plan with the lowest upfront cost in the country may not be for everyone, experts say. Medicare's open enrollment season just started, and the plan from insurer Humana and retail giant Walmart is getting attention.

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Anacetrapib Drops LDL, Raises HDL

November 17, 2010 6:42 am | by Marilynn Marchione | News | Comments

An experimental Merck drug safely boosted good cholesterol to record highs while dropping bad cholesterol to unprecedented lows in a study that stunned researchers and renewed hopes for an entirely new way of lowering heart risks.

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FDA Panel Backs New Lupus Treatment

November 17, 2010 6:39 am | by Marilynn Marchione | News | Comments

Federal health experts voted in favor of the first new drug to treat Lupus in over 50 years, setting aside concerns that the experimental therapy does not work in some key patient groups, including African-Americans.

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Zapping Nerves Helps Control High Blood Pressure

November 17, 2010 6:36 am | by Marilynn Marchione | News | Comments

Some people who couldn't get their blood pressure under control despite taking a fistful of pills every day found relief from an experimental treatment that shows promise as a permanent fix for the condition.

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Court Upholds Alimta Patent

November 16, 2010 7:53 am | News | Comments

Eli Lilly and Company announced that the trial on the validity of the compound patent for Alimta before the U.S. District Court for the District of Delaware ended this afternoon with a ruling from the court that judgment would be entered in Lilly's favor.

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Protea Expands Bioanalytical Laboratory

November 16, 2010 7:50 am | News | Comments

Protea Biosciences, Inc., a leading developer of technology for biomolecular analysis, announced that the company has completed an expansion of its GLP Bioanalytical Laboratory, including the introduction of quantitative proteomics mass spectrometry services.

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Gene Therapy Improves Condition in Wiskott-Aldrich

November 16, 2010 7:47 am | News | Comments

A pediatric immunologist at collaborated with European gene therapy researchers who achieved marked clinical improvements in two young children with Wiskott-Aldrich syndrome, a very rare but often severe immunodeficiency disorder.

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Diazoxide Slows Alzheimer's in Mice

November 16, 2010 7:42 am | News | Comments

A drug used decades ago to treat high blood pressure has been shown to improve learning and memory in mouse models of Alzheimer's disease, according to a new study by researchers at the National Institute on Aging.

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Merrion Preparing Phase 3 Orazol Study

November 16, 2010 7:37 am | News | Comments

After recent consultation with the FDA in November 2010, Merrion is preparing for its Phase 3 study for Orazol. If successful, the Phase 3 study will allow a new drug application for Orazol to be made under the FDA's abbreviated approval procedure.

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Effient Reduces Mortality in CABG

November 16, 2010 7:27 am | News | Comments

Results from an observational substudy from TRITON—TIMI 38 showed that patients treated with Effient prior to coronary artery bypass graft surgery had a reduced overall mortality rate compared to patients treated with Plavix.

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Mallinckrodt Chemicals Now Macron Chemicals

November 16, 2010 7:18 am | News | Comments

Avantor Performance Materials announced that it is renaming its Mallinckrodt Chemicals brand product line Macron Chemicals, as the company transitions away from its former Mallinckrodt Baker identity.

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Optivia And UCSF Receive Grant for Liver Tox Work

November 16, 2010 7:10 am | News | Comments

Optivia Biotechnology Inc. announced that it and the University of California, San Francisco, have received a SBIR grant to develop an innovative system for characterizing the role transporter proteins play in the disposition of drugs by the liver.

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First Stem Cell Trial for Stroke Patients

November 16, 2010 7:05 am | News | Comments

ReNeuron Group plc announces that the first patient has been treated with its ReN001 stem cell therapy for stroke in a ground-breaking UK clinical trial. PISCES is the world’s first fully regulated clinical trial of a neural stem cell therapy for disabled stroke patients.

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Pfizer Launches Global Centers for Therapeutic Innovation

November 16, 2010 6:57 am | News | Comments

Pfizer Inc. announced the establishment of the Global Centers for Therapeutic Innovation, an entrepreneurial network of partnerships with leading academic medical centers to transform research and development by accessing leading translational researchers.

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