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DDD Update

Daily news and top headlines for drug research professionals

Pfizer Requesting Cancer Drug Approval

June 1, 2011 6:46 am | News | Comments

Pfizer Inc. said it asked European Union regulators to approve its drug candidate axitinib as a treatment for advanced renal cell carcinoma in patients who haven't been helped by other therapies.

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FDA Approves DIFICID Tablets

June 1, 2011 5:50 am | News | Comments

The FDA has approved Optimer Pharmaceuticals' antibacterial drug DIFICID (fidaxomicin) tablets for the treatment of Clostridium difficile-associated diarrhea in adults.

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Mymetics’ Phase I Study on HIV Vaccine MYM-V101

May 31, 2011 1:14 pm | News | Comments

Mymetics Corporation reports its HIV-1 (Human Immunodeficiency Virus type 1) vaccine proved to be safe, well-tolerated, and demonstrated a high level of immunogenicity in a Phase I trial of 24 healthy women.

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Researchers Reveal Laboratory Mouse Details

May 31, 2011 1:10 pm | News | Comments

Mice and humans share about 95% of their genes, and mice are recognized as the leading experimental model for studying human biology and disease.

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FDA Approves Combivir

May 31, 2011 1:06 pm | News | Comments

The U.S. Food and Drug Administration (FDA) approved TEVA’s Abbreviated New Drug Application (ANDA) to market a generic version of ViiV Healthcare Company’s HIV treatment, Combivir Tablets (Lamivudine and Zidovudine).

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InSite Vision Joins Lawsuit Against Sandoz

May 31, 2011 1:03 pm | News | Comments

InSite Vision Incorporated reported it will join Merck and Pfizer Inc. in filing a patent infringement lawsuit against Sandoz Inc.

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Aegerion Pharma Posts New Lomitapide Study Data

May 31, 2011 12:55 pm | News | Comments

Aegerion Pharmaceuticals Inc. presented further late-stage study data for its drug candidate lomitapide on May 31, saying the drug is safe for lowering "bad" cholesterol and patients who continued to use it for more than a year maintained reductions.

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Excelimmune Completes $10.5 Million Series B Financing

May 31, 2011 12:36 pm | News | Comments

Excelimmune, Inc. announced that it will use the proceeds of $10.5 million in Series B financing  to advance Staphguard, a human recombinant polyclonal antibody (HRPA) candidate against methicillin-resistant Staphylococcus aureus (MRSA), toward the clinic and improve the company’s discovery platform and  proof-of-principle for its manufacturing systems.

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Molecular Blood Blotting Mystery Solved

May 31, 2011 12:29 pm | News | Comments

In a new study, researchers describe a chemical interaction between a clotting factor and a cell membrane that has baffled scientists for decades.

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Microplate Software Protocol

May 31, 2011 8:07 am | Product Releases | Comments

Thermo Fisher Scientific Inc. introduced a downloadable software protocol library for its Multiskan GO microplate spectrophotometer. There are currently 20 ready-made protocols available to cover a wide variety of photometric applications.

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DsiRNA Screening

May 31, 2011 7:52 am | Product Releases | Comments

Integrated DNA Technologies offers a comprehensive range of customizable products for RNA interference applications. The Screening Dicer-substrate siRNA provides researchers with a cost-effective and quick solution for their RNAi requirements.

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Noncoding RNA May Promote Alzheimer's

May 31, 2011 7:41 am | News | Comments

Researchers have pinpointed a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease or other types of neurodegeneration.

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SUNY Buffalo Picks Sage-N for Proteomics Research

May 31, 2011 7:34 am | News | Comments

Sage-N Research, Inc. announced that the State University of New York at Buffalo’s pharmaceutical sciences research group has chosen the SORCERER platform to assist with its advanced proteomics research.

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Gene Therapy Fails in Phase 3 Trial

May 31, 2011 7:24 am | News | Comments

Despite showing promising results in a recent phase 2 trial, administration of a novel gene therapy to enhance the growth of new blood vessels in people with critical limb ischaemia, does not reduce amputation or death.

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DTC Genetic Tests Inaccurate

May 31, 2011 7:10 am | News | Comments

Geneticists from the European Society of Human Genetics have found that direct-to-consumer genetic tests give inaccurate predictions of disease risks and believe that some of them should be banned.

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