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DDD Update

Daily news and top headlines for drug research professionals

Watson Meets Earning Estimates

January 13, 2011 5:33 am | News | Comments

Watson Pharmaceuticals Inc. said Wednesday its 2010 results were about equal to its expectations. The company said its earnings will be at the midpoint of its estimated range of $3.37 to $3.45 per share.

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Oregon Sues J & J Over Recall

January 13, 2011 5:30 am | News | Comments

Oregon Attorney General John Kroger has sued Johnson & Johnson and two subsidiaries, claiming consumers were exposed to defective supplies of Motrin by a delay in public disclosure of a recall.

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FDA Panel Votes No on Liprotamase

January 13, 2011 5:27 am | News | Comments

Drugmaker Eli Lilly and Co. Inc. said a panel of federal health advisers voted against an experimental treatment designed to aid digestion in patients with cystic fibrosis and other diseases that affect the pancreas.

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Cell Sorter

January 13, 2011 5:15 am | Product Releases | Comments

The MoFlo Astrios next-generation cell sorter from Beckman Coulter, Inc. leverages the stable fluidic design of the original MoFlo and the electronic processing of the MoFlo XDP.

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LCD Microscope Display

January 13, 2011 5:11 am | Product Releases | Comments

Carl Zeiss introduced a new generation of ergonomic and compact tissue culture microscopes with its Primo Vert Monitor. The traditional eyepiece has been replaced with an integrated digital camera and LCD display.

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Advanced Imaging Software for Western Blot Analysis

January 13, 2011 5:06 am | by Stephanie R. Noles, PhD, Global In Vitro Product Manager Carestream Molecular Imaging, Woodbridge, Conn. | Articles | Comments

Protein analysis has quickly become as integral a component of the drug discovery process as genomics. The examination of protein expression levels and post-translational modifications helps identify new drug targets.

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Fluorescent Western Blotting: A Quantitative Approach

January 13, 2011 4:54 am | by Amy Schutz-Geschwender, PhD, Principal Scientist; LI-COR Biosciences, Lincoln, Neb. | Articles | Comments

For decades, researchers have used Western blotting to confirm the presence of a target protein in a complex sample. After gel electrophoresis, proteins are transferred to a membrane and interrogated with antibodies.

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High Throughput Western Blotting

January 13, 2011 4:32 am | by Jeff Xu, Product Manager, Blotting and Stains, Bio-Rad Laboratories, Inc., Hercules, Calif. | Articles | Comments

Western blotting involves the transfer of proteins from a gel matrix to a membrane following protein electrophoresis. This process serves as a bridge between protein separation and identification.

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QIAGEN Gains Minority Stake in Alacris

January 11, 2011 11:54 am | News | Comments

QIAGEN has signed an agreement for the acquisition of a strategic stake in Alacris Theranostics GmbH, a German start-up company using novel technologies to develop individualized cancer treatment strategies based upon a patient’s genomic profile.

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Genzyme Quarterly Growth Falls Short

January 11, 2011 11:52 am | News | Comments

Genzyme Corp. said that it expects to report adjusted profit and revenue growth in the fourth quarter, but the preliminary results fell short of Wall Street expectations.

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New Scoring System for PTEN Mutation

January 11, 2011 11:49 am | News | Comments

Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers.

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Protective Protein Also Causes Atherosclerosis

January 11, 2011 11:47 am | News | Comments

UCLA researchers have found that a protein that plays an important role in some antioxidant therapies may not be as effective due to additional mechanisms that cause it to promote atherosclerosis, or clogging of the arteries.

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3D Tissue Modeling System

January 11, 2011 11:43 am | Product Releases | Comments

The Automation Partnership (TAP) announced a new 12-well version of RAFT (Real Architecture for 3D Tissue), its system for generating reproducible, 3D collagen tissue models.

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sCMOS-based Camera

January 11, 2011 11:37 am | Product Releases | Comments

Andor Technology plc launched the Neo camera platform based on next-generation scientific CMOS (sCMOS) technology. The platform offers ultra-low noise, extremely fast frame rates, wide dynamic range, high resolution and a large field of view.

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Raising the High Content Bar

January 11, 2011 11:25 am | by Mike May, PhD, Contributing Editor | Articles | Comments

 To see how compounds impact cells, many researchers now use high content approaches. Typically, this involves automatically capturing and photographing cells, and then applying image analysis.

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