Researchers in Europe reported that treatment with modified-release sildenafil significantly reduced the frequency of attacks of Raynaud's phenomenon in patients with limited cutaneous systemic sclerosis, also known as scleroderma.
Researchers have found that systemic inflammation caused by sepsis can be suppressed by a protein which occurs naturally in the roundworm Acanthocheilonema viteae.
A group of researchers has discovered that a class of chemotherapy drugs originally designed to inhibit key signaling pathways in cancer cells also kills the parasite that causes malaria.
A recent trial of rituximab in combination with a tumor necrosis factor inhibitor and methotrexate in patients with active rheumatoid arthritis found the safety profile to be consistent with other RA trials with TNF inhibitors.
Hidden financial conflicts-of-interest are sneaking into published drug research through the back door, warns an international team of investigators.
Thermo Fisher Scientific Inc. has introduced the ToxInsight DILI Assay Cartridge, a tool for assessing the liver toxicity risk of chemical compounds. It will help pharmaceutical companies better assess liver toxicity early in the drug development process.
Toxikon Corp. has completed toxicity studies in two species for Cellceutix Corp.’s Kevetrin, a compound being developing for the treatment of resistant lung and breast cancers.
Transparent Inc. announced that it has developed a more advanced medium for Cell-able, a human hepatocyte array kit that has the potential to reduce drug development costs and time-to-market for pharmaceutical companies.
Battelle experts will debut a new industry-leading, multi-scale toxicology program as a way to more effectively advance drug development during a Battelle symposium on March 7-10 at the 2011 Society of Toxicology Annual Meeting.
RainDance Technologies, Inc. and Ambry Genetics announced a new collaboration focused on the development and commercialization of a comprehensive drug absorption, distribution, metabolism, and excretion genetic screening panel for use on next-generation sequencing systems.
Highlights of Pall’s product showcase include AcroPrep Advance Filter Plates, Microsep Advance and Macrosep Advance Ultrafiltration Centrifugal Devices, and acrodisc PSF Syringe Filters.
EMD Millipore announced the introduction of an all-in-one water purification system designed specifically for clinical analyzers. The Elix Gulfstream Clinical water purification system will provide up to 100 liters per hour of clinical laboratory reagent water daily.
Covance Inc. announced that its Seattle-based genomics laboratory has initiated a collaboration with the Institute for Systems Biology to further understand the area of brain tumor biology.
Specialty drug maker Hospira Inc. said that it had hired Allergan Inc. President F. Michael Ball to become its new chief executive and member of the board.
Working as part of a public program to screen compounds to find potential medicines and other biologically useful molecules, scientists have discovered an extremely potent class of potential anti-cancer and anti-neurodegenerative disorder compounds.