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DDD Update

Daily news and top headlines for drug research professionals

DDI Reality via Virtual Studies

September 13, 2010 7:41 am | by Steve Toon, PhD; Executive Director; Elizabeth Kingsley, PhD; PR Coordinator; Simcyp Limited; Sheffield, UK | Articles | Comments

Simulation of drug-drug interactions anticipate in vivo outcomes.

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Shedding A New Light on GPCRs

September 13, 2010 7:08 am | by Jean-Luc-Tardieu, PhD; Product Manager; Cisbio Bioassays; Bagnols-sur-Cèze, France | Articles | Comments

Fluorescent assay methods aid GPCR investigation in the discovery and development of therapeutic antibodies.

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ADME Picks Up Speed

September 13, 2010 6:49 am | by Alan Dove, PhD, Contributing Editor | Articles | Comments

Pharmacokinetic assays have traditionally been a bottleneck in lead optimization, but a new generation of technologies is increasing the throughput of these critical tests.

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Cell Migration and Invasion Assay

September 10, 2010 8:19 am | Product Releases | Comments

TTP LabTech has joined forces with Platypus Technologies to offer automated solutions for studying the migration and invasion profiles of different cell lines using the Acumen eX3 laser scanning microplate cytometer.

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Bausch + Lomb Pharma Appoints New President

September 10, 2010 7:55 am | News | Comments

Bausch + Lomb, the global eye health company, has named Daniel M. Wechsler as corporate vice president and global president of its Pharmaceuticals business.

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Sanofi Denies Raising Genzyme Offer

September 10, 2010 7:51 am | News | Comments

French drugmaker Sanofi-Aventis SA is sticking to its original offer of $69 a share to buy U.S. biotech company Genzyme Corp., according to a Sanofi spokesman.

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Metastatic Melanoma Treatment Fast-Tracked By FDA

September 10, 2010 7:34 am | News | Comments

In a phase 3 study, researchers randomly assigned patients to one of three treatment groups: those receiving ipilimumab plus an inactive version of gp 100 (a cancer vaccine); those receiving ipilimumab plus gp 100; and those receiving gp 100 plus ipilimumab placebo.

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Hopkins Scientists Find Key to Staying Pluripotent

September 10, 2010 7:25 am | News | Comments

Researchers have determined why certain stem cells are able to stay stem cells. An enzyme that changes the way DNA is packaged in cells allows specific genes to be turned on and off, thereby preventing a stem cell from becoming another cell type.

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Shire Licenses DMD Drug Candidate

September 10, 2010 6:58 am | News | Comments

Shire plc announced the expansion of its Human Genetic Therapies pipeline through the exclusive license, in markets outside of North America, for the activin receptor type IIB (ActRIIB) class of molecules being developed by Acceleron Pharma Inc.

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Daiichi Sankyo Wins Patent Case Against Mylan

September 10, 2010 6:54 am | News | Comments

Daiichi Sankyo Company, Limited announced that the United States Court of Appeals has affirmed the U.S. District Court decision in patent litigation against Mylan, upholding the validity of the Daiichi Sankyo U.S. patent covering Benicar, Benicar HCT, and AZOR.

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FDA Adds Warning Label to Imaging Drugs

September 10, 2010 6:45 am | by Matthew Perrone | News | Comments

Federal health regulators are warning doctors that a class of injectable drugs used in MRI medical imaging scans can cause a rare and sometimes fatal condition in patients with kidney disease.

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Activists Call for Greater AIDS Funding

September 10, 2010 6:42 am | by Donna Bryson | News | Comments

Doctors and AIDS activists urged African governments to fulfill a decade-old pledge to spend more of their own money on health if they want international help in fighting AIDS.

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Personal Microarray Solution

September 9, 2010 12:15 pm | Drug Discovery & Development | Product Releases | Comments

Affymetrix has launched the GeneAtlas System, which offers a complete personal solution for processing Affymetrix microarrays including stations for fluidics, imaging and hybridization, a computer workstation, and analysis software.

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Colony Formation Assay

September 9, 2010 8:48 am | Product Releases | Comments

TTP LabTech has validated a new cell colony formation assay on the Acumen eX3 fluorescence microplate cytometer in collaboration with ChemPartner.

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ISCA-UPD Array

September 9, 2010 8:44 am | Product Releases | Comments

Oxford Gene Technology (OGT), provider of clinical genetics and diagnostic solutions to advance molecular medicine, has introduced the CytoSure ISCA UPD 4 x 180k array.

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