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DDD Update

Daily news and top headlines for drug research professionals

Automated Sample Preparation

March 15, 2011 8:00 am | Product Releases | Comments

Scientists know that the most important part of mass spec analysis is the preceding separation steps. That is why Perfinity integrated their proprietary automation and column technologies into Shimadzu instrumentation.

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LC Method Transfer

March 15, 2011 7:55 am | Product Releases | Comments

Agilent Technologies introduced the Intelligent System Emulation Technology which allows the 1290 Infinity LC to emulate other systems for transfer of methods between LCs, regardless of brand.

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Reducing Healthcare Costs With Electronic Data Capture

March 15, 2011 7:44 am | by Bruce Schatzman, CEO, StudyManager, Seattle, Wash. | Articles | Comments

It’s no secret that the cost of healthcare has skyrocketed. A primary reason is the expense of taking a drug or device through a lengthy clinical development process, which can last 8 to 10 years and cost upwards of $1 billion.

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Combining Clinical Trials With PPD PatientView

March 15, 2011 7:38 am | by Dave Agrella, executive director, information technology; Jeremy Botkin, associate manager, information technology; PPD, Inc., Wilmington, N.C. | Articles | Comments

As clinical trials grow longer the retention rates for study participants have dropped sharply. Having a patient drop out of a clinical trial is not only costly and frustrating, but also impacts the statistical research records and status of the trial.

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HPLC Column

March 14, 2011 8:33 am | Product Releases | Comments

Thermo Fisher Scientific Inc. announced the new Syncronis HPLC column range. The new range delivers consistent, predictable separations, from run to run and column to column.

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High Performance Mass Spectrometer

March 14, 2011 8:28 am | Product Releases | Comments

The Citius LC-HRT system utilizes LECO’s Folded Flight Path technology to provide full-range mass spectra at speeds of over 100 spectra per second, and resolutions of up to 100,000 with high-performance mass accuracy.

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A Focus on the Treatment of Transthyretin-Mediated Amyloidosis

March 14, 2011 8:10 am | by Dinah Sah, PhD, Vice President, Research; Alnylam Pharmaceuticals, Cambridge, MA | Articles | Comments

Since its discovery in 1981, RNA interference—a naturally occurring cellular mechanism for regulating all genes—has been recognized not only as a major breakthrough in cell biology, but also as the basis for a new, transformative class of drugs.

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Dealing with Increasing Protocol Complexities in Phase 1

March 14, 2011 8:05 am | by Mark Cusack, VP Business Development, Logos Technologies Inc, London, UK | Articles | Comments

Research carried out by Tufts' Center for the Study of Drug Development in 2010 has shown that protocol complexity, as measured by the number of unique procedures, their frequency, and the number of subject eligibility criteria, has risen dramatically.

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Nanoscale HPLC

March 14, 2011 8:00 am | Product Releases | Comments

Thermo Fisher Scientific Inc. announced the release of the EASY-Column for nanoscale HPLC applications. Nanoscale HPLC is primarily used in combination with high performance mass spectrometry for the analysis of complex biological samples.

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Pipette Management Software

March 14, 2011 7:57 am | Product Releases | Comments

Artel has launched version 3.3 of its Pipette Tracker software. Tightly integrated with the Artel Pipette Calibration System, Pipette Tracker provides a total management system for quality control of any pipette population.

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Ardea Revenue Doubles in Q4

March 14, 2011 7:48 am | News | Comments

Ardea Biosciences Inc. said its fourth-quarter loss narrowed considerably as a $15 million milestone payment helped the biotech company's revenue double.

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Lilly to Acquire Janssen Animal Health Business

March 14, 2011 7:42 am | News | Comments

The drugmaker Eli Lilly and Co. said it plans to buy the animal health business of Janssen Pharmaceutical NV in a deal that would give Lilly's Elanco division about 50 marketed animal health products.

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Findings Show How Good Cholesterol Protects the Body

March 14, 2011 7:36 am | News | Comments

Researchers have determined the structure of human HDL cholesterol and say the finding could help explain how this "fat packet" protects against cardiovascular diseases, including heart attack and stroke.

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Tumors Grow in Bursts Say Researchers

March 14, 2011 7:33 am | News | Comments

A new method of analyzing cancerous tumors developed by scientists at Cold Spring Harbor Laboratory suggests that tumors may not evolve gradually, but rather in punctuated or staccato-like bursts.

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Otelixizumab Flops in Phase 3 Trial

March 14, 2011 7:19 am | News | Comments

Tolerx Inc. and GlaxoSmithKline PLC said their potential diabetes drug failed to meet its goal in a late-stage study. The companies are studying otelixizumab as a potential treatment for patients with Type 1 diabetes.

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