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DDD Update

Daily news and top headlines for drug research professionals

Tracking Biological Changes

March 9, 2011 10:26 am | by Jeffrey D. Peterson, Head of Applied Biology; PerkinElmer, Waltham, Mass. | Articles | Comments

Researchers are expanding their use of in vivo imaging with fluorescence in order to quantify important biological changes associated with disease. However, this imaging modality faces significant challenges when applied to living animals.

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Metabolomics: The Pulse Quickens

March 9, 2011 10:20 am | by Alan Dove, PhD; Contributing Editor | Articles | Comments

Aided by a new generation of technologies, drug discovery labs are pushing the boundaries of the latest ‘omics trend: metabolomics.

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A Long Way to the Bedside

March 9, 2011 10:13 am | by Catherine Shaffer, Contributing Editor | Articles | Comments

Recent years have seen rapid technological progress in the fields supporting personalized medicine, from biomarker discovery to mapping the genome to pushing back the frontiers of mass spec sensitivity.

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Laboratory Pilot Mixing System

March 9, 2011 7:34 am | Product Releases | Comments

A new in-line multi-component laboratory pilot system for blending multiple streams of fluids and manufacturing homogeneous emulsions, dispersions, and blends is being introduced by Bematek Systems, Inc.

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Fluorescent Array Imaging Reader

March 9, 2011 7:19 am | Drug Discovery & Development, Drug Discovery & Development | Product Releases | Comments

The FLAIR from Sensovation is a compact, CCD-camera based reader that enables the user to quickly and sensitively read and analyze whole arrays of fluorescent assays at the bottom of each well of a 96-well plate.

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Sigma Adds 1,400 New Cell Lines

March 9, 2011 7:03 am | News | Comments

Sigma Life Science has announced the addition of 1,400 new European Collection of Cell Culture cell lines to its collection of cell line cultures and services. These cell lines have been fully authenticated and tested free of mycoplasma.

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Cipher Income Up $700K in Fourth

March 9, 2011 6:59 am | News | Comments

Cipher Pharmaceuticals Inc. reports net income of $100,000 or nil per share in its fourth quarter, compared with a loss of $600,000 or three cents per share in the same period last year.

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FDA Reviewing Carbinoxamine XR NDA

March 9, 2011 6:56 am | News | Comments

Tris Pharma announced that the US Food and Drug Administration has accepted its Extended Release Carbinoxamine Oral Suspension NDA for the treatment of allergies in kids two years and older.

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New Leukemia Treatment Given Orphan Drug Status

March 9, 2011 6:53 am | News | Comments

Stemline Therapeutics, Inc. announced that SL-401 has received Orphan Drug designation from the U.S. Food and Drug Administration for the treatment of acute myeloid leukemia.

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Mallinckrodt Chemicals Changes Name

March 9, 2011 6:49 am | News | Comments

Avantor Performance Materials (formerly Mallinckrodt Baker) announced that its Mallinckrodt Chemicals product brand name has officially changed and will now be referred to as Macron Chemicals.

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Genzyme CEO Could Pocket $221M from Buyout

March 9, 2011 6:45 am | News | Comments

The longtime chief executive of biotech firm Genzyme stands to make up to $221 million from the company's pending sale to French pharmaceutical giant Sanofi-Aventis.

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Secrets of Plague Revealed by STORM

March 9, 2011 6:43 am | News | Comments

In work that is pushing the "diffraction barrier" associated with microscopic imaging of living cells, researchers demonstrated the power of a new super-resolution microscopy technique which can simultaneously image multiple molecules in living immune cells.

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ADAM-12 Could Hold Key To Treating Lethal Ailments

March 9, 2011 6:37 am | News | Comments

ADAM-12 is the name of a gene that researchers believe could one day be an important element in the fight against cancer, arthritis, and cardiac hypertrophy, or thickening of the heart's walls.

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Sildenafil Reduces Raynaud's Frequency in lcSSc

March 9, 2011 6:33 am | News | Comments

Researchers in Europe reported that treatment with modified-release sildenafil significantly reduced the frequency of attacks of Raynaud's phenomenon in patients with limited cutaneous systemic sclerosis, also known as scleroderma.

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Roundworm Could Provide Sepsis Treatment

March 9, 2011 6:30 am | News | Comments

Researchers have found that systemic inflammation caused by sepsis can be suppressed by a protein which occurs naturally in the roundworm Acanthocheilonema viteae.

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