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DDD Update

Daily news and top headlines for drug research professionals

NeuroVive Conducting Late-Stage NeuroSTAT Trial

March 8, 2011 6:39 am | News | Comments

NeuroVive has signed an agreement with the European Brain Injury Consortium to conduct a European multi-center Phase 2/3 clinical trial of NeuroSTAT for neuroprotection in patients with traumatic brain injury.


FDA Wants More Info on Xifaxan

March 8, 2011 6:32 am | News | Comments

Salix Pharmaceuticals Ltd. confirmed that the Food and Drug Administration wants more information about Salix's irritable bowel syndrome treatment Xifaxan, and is not ready to grant a new marketing approval.


FDA Accepts Dapagliflozin Application

March 8, 2011 6:29 am | News | Comments

AstraZeneca PLC and Bristol-Myers Squibb Co. say the U.S. Food and Drug Administration has accepted for review a new drug application for diabetes drug dapagliflozin.


Lycera Announces Research Collaboration with Merck

March 7, 2011 7:40 am | News | Comments

Lycera Corporation has entered into an exclusive research collaboration with Merck to discover, develop and commercialize small molecules that target T-helper 17 (Th17) cells, key mediators of inflammation.


Sanofi Extends Offer for Genzyme

March 7, 2011 7:33 am | News | Comments

France's Sanofi-Aventis SA says it will extend its cash buyout offer for Genzyme until next month, as part of its agreed $20.1 billion takeover of the U.S.-based specialty drugmaker.


Clinical Trial Data Coding Update

March 7, 2011 7:29 am | Drug Discovery & Development | Product Releases | Comments

Oracle announced Oracle Health Sciences Central Coding Release 3.0, a Web-based clinical trial data coding and dictionary management that promotes greater productivity for clinical trial teams.


Two Camera Imaging Adapter

March 7, 2011 7:27 am | Drug Discovery & Development | Product Releases | Comments

Andor Technology plc launched the TuCam adapter for simultaneous two camera imaging.


Scientists Create Cell Assembly Line

March 7, 2011 7:23 am | News | Comments

Borrowing a page from modern manufacturing, scientists from the Florida campus of The Scripps Research Institute have built a microscopic assembly line that mass produces synthetic cell-like compartments.


Normal White Blood Cells May Cause Rare Leukemia

March 7, 2011 7:20 am | News | Comments

New research has identified a small subset of normal white blood cells in the body that gives rise to a rare incurable form of leukemia.


Symphogen Receives U.S. Patent on Lead Cancer Compound

March 7, 2011 7:12 am | News | Comments

Symphogen has been granted a U.S. patent for Sym004 as well as other antibody compositions containing at least two distinct anti-EGFR antibodies having certain binding characteristics.


Primary Endpoints Met In Phase 3 Trial of Tofacitinib

March 7, 2011 7:10 am | News | Comments

Pfizer Inc. announced that the ORAL Sync Phase 3 study of tofacitinib,  an investigational, novel, oral JAK inhibitor, being studied in moderate-to-severe rheumatoid arthritis, met its primary endpoints.


Roche, RainDance Collaborate in Targeted Sequencing for ADME Research

March 7, 2011 7:04 am | News | Comments

RainDance Technologies, Inc., and 454 Life Sciences announced a collaboration for the development and commercialization of a targeted next-generation sequencing (NGS) solution for the investigation of drug absorption, distribution, metabolism, and excretion (ADME).


Cardiomyocyte Biomarker Testing Revealed

March 7, 2011 7:00 am | News | Comments

GE Healthcare announced preliminary data from its ongoing structural cardiomyocyte biomarker collaboration with Genentech at the 50th Annual Meeting of The Society of Toxicology (SOT) in Washington D.C.


Japan Halts Vaccines After Deaths of 4 Children

March 7, 2011 6:55 am | News | Comments

Japan has temporarily stopped using vaccines from U.S. drugmaker Pfizer Inc. and Sanofi-Aventis SA of France while it investigates the deaths of four children who were inoculated, the health ministry said.


AstraZeneca Ends Production of Asthma Inhaler

March 7, 2011 6:53 am | News | Comments

AstraZeneca PLC is ending production of one version of its asthma drug Pulmicort immediately because of technical problems in manufacturing.



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