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DDD Update

Daily news and top headlines for drug research professionals

FDA Fast Tracking Regorafenib

May 10, 2011 10:34 am | News | Comments

Bayer HealthCare Pharmaceuticals Inc. said that the Food and Drug Administration will conduct a fast track review of its cancer drug candidate regorafenib.

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Avanir Loss Grows in 2Q

May 10, 2011 10:29 am | News | Comments

Avanir Pharmaceuticals Inc. reported a bigger loss for its fiscal second quarter due to costs to launch the drug Nuedexta. Nuedexta is the first and only FDA-approved treatment for pseudobulbar affect.

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Remicade Meets UC Study Goals

May 10, 2011 10:23 am | News | Comments

Johnson & Johnson said that its drug Remicade met key goals in treating pediatric patients with moderate to severe ulcerative colitis in a late-stage study.

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DavosPharma to Market Immunologix’s Antbodies

May 10, 2011 8:05 am | News | Comments

Immunologix, Inc., Charleston, S.C., and DavosPharma, Upper Saddle River, N.J. have formed a strategic alliance whereby DavosPharma, a provider of discovery, chemistry, and formulation services, will represent and market 100% human antibodies produced by Immunologix.

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OncoGenex provided an update on recent drug development and clinical trial activities

May 10, 2011 8:00 am | News | Comments

The company is currently enrolling a Phase 3 clinical trial referred to as SYNERGY, to be conducted in approximately 123 cancer centers to evaluate a survival benefit for custirsen in combination with first-line docetaxel treatment in approximately 800 patients with castration-resistant prostate cancer (CRPC).

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OGI Genomics Researchers Awarded $23 million

May 10, 2011 7:49 am | News | Comments

The Ontario Genomics Institute (OGI) has been awarded $23.8 million to support genomics research. $11.3 million from Genome Canada and $12.5 million from co-funding.

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Kancera, Northwestern Collaborate on Cancer Research

May 10, 2011 7:42 am | News | Comments

Kancera AB and has launched a collaborative research effort with Mary Hendrix and her research group at The Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Feinberg School of Medicine.

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Shire Options Heptares GPCR Target

May 10, 2011 7:37 am | News | Comments

Heptares Therapeutics signed an exclusive option agreement granting Shire Pharmaceuticals an exclusive option, upon completion of certain preclinical studies, to license worldwide development and commercial rights to the Heptares novel adenosine A2A antagonist.

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Cellzome, Neusentis to Study Epigenetic Factors

May 10, 2011 7:31 am | News | Comments

Cellzome and Neusentis, Pfizer’s Pain & Sensory Disorders and Regenerative Medicine unit, will collaborate to characterize epigenetic factors involved in stem cell differentiation using Cellzome’s EpisphereTM technology.

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MS therapy Could Kill Brain Cells

May 10, 2011 6:47 am | News | Comments

Researchers with the Faculty of Medicine & Dentistry at the University of Alberta discovered that some “protective” T-cells can kill neurons.

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RM-131 Restores GI Function

May 10, 2011 6:40 am | News | Comments

Biotech company Rhythm announced results that demonstrated RM-131 were effective in restoring normal gastric function in animal models of delayed gastric emptying owing to a direct prokinetic effect.

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USCF Produces Botulism Antitoxin

May 10, 2011 6:31 am | News | Comments

Basic research conducted at the University of  California, San Francisco (UCSF) into botulism has translated into a novel antitoxin to protect against bioterrorism and  the first clinical trials to assess the resulting vaccine’s safety may launch soon.

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3D Proteins: Getting the Big Picture

May 10, 2011 5:51 am | by Miles O'Brien, Science Nation Correspondent, Marsha Walton, Science Nation Producer | News | Comments

Instead of viewing proteins in a two-dimensional textbook, students at the University of Arkansas in Fayetteville are working with a three-dimensional display to study proteins from the inside out.

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Biotech Drug Approvals Nearly Doubled in Last Decade

May 10, 2011 5:42 am | News | Comments

U.S. regulatory approvals for new biopharmaceuticals nearly doubled in the last decade, compared to the 1990s, but drug developers "face substantial challenges" if they are to maintain that pace.

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Suit Blames Stop-smoking Drug for Killings

May 10, 2011 5:36 am | News | Comments

The fathers of two people killed in a western Pennsylvania murder-suicide say a smoking cessation drug is to blame.

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