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DDD Update

Daily news and top headlines for drug research professionals

Acacia Begins Phase 2 Trial of CINV Drug

February 16, 2011 5:25 am | News | Comments

Acacia Pharma has initiated a dose-escalating, Phase 2a proof-of-concept study of APD421, is an intravenous formulation of a currently marketed dopamine D2 antagonist for the new use of prevention and treatment of nausea & vomiting.

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NIH Study Finds Possible Heart Disease Risk Factor

February 16, 2011 5:23 am | News | Comments

Abnormal heart rate turbulence is associated with an increased risk of heart disease death in otherwise low-risk older individuals, according to a study funded by the National Heart, Lung, and Blood Institute.

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Good Diet Helps Fight Alzheimer's Genes

February 16, 2011 5:20 am | News | Comments

Scientists today agree that there are five molecules that are known to affect or cause Alzheimer's disease, which plagues an estimated five million Americans. The potency of these molecules is linked to environmental factors such as diet and lifestyle.

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New Tools Help Study Lifecycle of Cancer

February 16, 2011 5:17 am | News | Comments

Scientists have developed new synthetic molecules as models to study the structural and functional role of the proline residue and tetrapeptide sequence important for the regulation of cancer cell apoptosis by the XIAP protein.

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Protein Provides New Approach to TB Treatment

February 16, 2011 5:15 am | News | Comments

Recently published findings present possible new opportunities for developing organism-specific drugs, which target the pathogen that causes tuberculosis but leave other microorganisms, which are beneficial to us, untouched.

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Ligand Reports Decreased Profits

February 16, 2011 5:11 am | News | Comments

Ligand Pharmaceuticals Inc. reported a smaller fourth-quarter profit compared to a year ago, when one-time payments boosted its revenue. Ligand said its net income fell to $2.4 million.

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Drug May Slow Growth of Early Prostate Cancer

February 16, 2011 5:08 am | by Marilynn Marchione | News | Comments

A new study suggests a way to help men with early, low-risk prostate cancer avoid being overtreated for a disease that in most cases will never threaten their lives. It found that a drug can slow the growth of these tumors in men who opt to be monitored instead of having treatment right away.

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More Recall Problems for J & J

February 16, 2011 5:06 am | News | Comments

A unit of Johnson & Johnson has recalled 70,000 syringes of its antipsychotic drug Invega Sustenna after finding that some of the pre-filled syringes may have cracks which possibly could affect the drug's sterility.

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Novo Nordisk Subpoenaed Over Marketing

February 16, 2011 5:04 am | News | Comments

Novo Nordisk A/S says it has been subpoenaed by the U.S. Attorney for the District of Massachusetts in an investigation of how the Danish pharmaceutical company markets three diabetes drugs.

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Sanofi Buying Genzyme for $20.1B

February 16, 2011 5:03 am | by Greg Keller | News | Comments

French drug maker Sanofi-Aventis SA has agreed to buy Genzyme Corp. in a sweetened all-cash $20.1 billion deal that ends months of corporate haggling and positions Sanofi at the forefront of the market in lucrative drugs for rare genetic disorders.

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Optimizing Therapeutic and Diagnostic Monoclonal Human Antibodies

February 15, 2011 10:25 am | by Markus Enzelberger, PhD, Head of Discovery Alliances & Technologies, MorphoSys AG, Munich, Germany | Articles | Comments

The development of monoclonal antibodies as therapies and as diagnostics has made tremendous advances since the approval of the first therapeutic mAb 25 years ago. New technologies have enabled the synthesis of fully human mAbs.

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NG Class Detegents

February 15, 2011 7:11 am | Product Releases | Comments

Affymetrix, Inc. launched its Anatrace brand Neopentyl Glycol Class Detergents, the next generation of detergents to significantly advance the study of integral membrane proteins, the most important proteins found in the human genome.

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Colony Picker

February 15, 2011 7:09 am | Drug Discovery & Development | Product Releases | Comments

Tecan and SciRobotics announced the launch of the integrated Pickolo colony-picker for the Freedom EVO liquid handling platforms, providing customers with a complete solution for automation of molecular biology workflows, from cloning to PCR sequencing or cell-based screening.

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BioConvergence And Creapharm Partner

February 15, 2011 7:04 am | News | Comments

BioConvergence and Creapharm have combined their strengths to offer the biotech and pharmaceutical industries experienced talent and a variety of services required during preclinical and early stage clinical phases.

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Jomaa And MMV Working on New Anti-Malarial

February 15, 2011 6:58 am | News | Comments

Jomaa Pharma GmbH and Medicines for Malaria Venture announced that they have signed a Memorandum of Understanding for the joint development of fosmidomycin, as a component of non-artemisinin based combination therapy, for acute Plasmodium falciparum malaria.

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