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DDD Update

Daily news and top headlines for drug research professionals

New Oncogene Linked to Common Lung Cancer

July 28, 2010 7:16 am | News | Comments

The identification of the oncogene, BRF2, specific to lung squamous cell carcinoma suggests that genetic activation of this oncogene could be used as an identification marker for this type of lung cancer.

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Protein Critical to Skeletal Development

July 28, 2010 7:13 am | News | Comments

Too little of a protein called neogenin results in a smaller skeleton during development and sets the stage for a more fragile bone framework lifelong, Medical College of Georgia researchers report.

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Coral Pigment Helps Live-Cell Imaging

July 28, 2010 7:03 am | News | Comments

Scientists have shown that a variant form of a fluorescent protein originally isolated from a reef coral has excellent properties as a marker protein for super-resolution microscopy in live cells.

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Hypertension Predictable As Early as 17

July 28, 2010 6:58 am | News | Comments

Ben-Gurion University of the Negev researchers reveal in a new, large-scale study that "normal" blood pressure at age 17 can still predict hypertension at early adulthood and that teenage boys are three to four times more likely to develop high blood pressure in early adulthood than girls.

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Dynavax Begins Universal Flu Vaccine Study

July 28, 2010 6:53 am | News | Comments

Dynavax Technologies Corporation reported completing enrollment and the first immunizations of 39 subjects enrolled in its Phase 1 study of the company's Universal Flu vaccine.

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Tibotec Submits NDA for Rilpivirine

July 28, 2010 6:34 am | News | Comments

Tibotec Pharmaceuticals has submitted a New Drug Application to the U.S. Food and Drug Administration for TMC278 (rilpivirine), an investigational non-nucleoside reverse transcriptase inhibitor, for once-daily use in treatment-naïve HIV-1-infected adults.

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FDA Grants Cladribine Priority Review

July 28, 2010 6:30 am | News | Comments

Merck KGaA announced that the U.S. Food and Drug Administration has accepted for filing the New Drug Application for cladribine tablets as a therapy for relapsing forms of multiple sclerosis.

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Laser-Activated Nanoparticles Allow Swift Delivery

July 28, 2010 6:25 am | News | Comments

Using chemical "nanoblasts" that punch tiny holes in the protective membranes of cells, researchers have demonstrated a new technique for getting therapeutic small molecules, proteins and DNA directly into living cells.

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Caremark Earnings Weak, Hope on the Horizon

July 28, 2010 5:58 am | News | Comments

CVS Caremark Corp. said it struck a large pharmacy benefit management services contract with health insurer Aetna Inc., but confidence fell as the pharmacy chain reported weaker earnings and trimmed its profit forecast.

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Cytotoxicity Imaging

July 27, 2010 8:28 am | Product Releases | Comments

Genetix, a leading provider of solutions for imaging and image analysis, announces the availability of an independent, peer-reviewed publication comparing cytotoxicity testing using its CloneSelect Imager system against the conventional, widely-used, colorimetric MTT assay.

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Interaction Analysis

July 27, 2010 8:25 am | Drug Discovery & Development | Product Releases | Comments

GE Healthcare has launched the Biacore T200, designed to deliver exceptional sensitivity in the measurement of high-quality kinetic, affinity, concentration, specificity, and thermodynamic interaction data, in real time.

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AbD Serotec Signs Deal With University College London

July 27, 2010 8:08 am | News | Comments

AbD Serotec has signed an exclusive license agreement with University College London Business PLC to provide AbD Serotec with access to a potent anti-PTH antibody for commercial use in research and diagnostic applications.

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NovImmune to Supply Genentech With Antibodies

July 27, 2010 8:00 am | News | Comments

NovImmune, an antibody-focused research and development biotech company, has entered into an exclusive licensing agreement with Genentech Inc. for a proprietary anti-IL-17 fully human monoclonal antibody, and access to back-up antibodies.

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Herpes Protein Allows Cellular Invasion

July 27, 2010 7:54 am | News | Comments

The mechanism by which a herpes virus invades cells has always been a mystery to scientists, but now researchers have revealed that the unusual structure of a key member of the protein complex allows the herpes virus to enter cells.

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Key to Intensive Lupus Treatment Discovered

July 27, 2010 7:49 am | News | Comments

Researchers at UT Southwestern Medical Center have uncovered the biological rationale for why large doses of corticosteroids given repeatedly over several weeks may help individuals with lupus.

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