Drug Discovery & Development

Strategies & Technologies Driving Drug Discovery to Market

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DDD Update

Daily news and top headlines for drug research professionals

Closing the Lab Information Gap

March 5, 2009 5:02 am | by Kim Shah, VP Marketing & Business Development, Thermo Fisher Scientific, Informatics | Articles | Comments

Integrating lab data into business enterprise systems can drive both research processes and business decisions.

New Hope for Sufferers of Muscle Wasting Diseases

March 5, 2009 4:50 am | News | Comments

An experimental procedure that strengthens stem cells’ ability to regenerate damaged tissue could offer new hope to sufferers of muscle-wasting diseases such as myopathy and muscular dystrophy.

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Wyeth Comments on Wyeth v. Levine Ruling

March 5, 2009 4:36 am | News | Comments

A Wyeth statement called the US Supreme Court’s ruling in Wyeth v. Levine "disappointing, not only for Wyeth, but for patients and public health in general".

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Seeking Out Sepsis

March 5, 2009 4:26 am | by Mike May, PhD, Contributing Editor | Articles | Comments

Sepsis, a blood-borne bacterial infection, can kill as many as 60 percent of the people who contract it.

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A Model Dilemma

March 5, 2009 3:59 am | by Catherine Shaffer, Contributing Editor | Articles | Comments

Cell-based toxicogenomics studies are emerging as an alternative to animal testing. But for now, animal models are the necessary choice.

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Human vs. Rodent

March 5, 2009 3:37 am | by D. Lansing Taylor, PhD, Founder, President and CEO, Cellumen, Inc., Pittsburgh, PA. | Articles | Comments

In vitro toxicity testing has been used for many years, but the predictive power for either rodent, or human toxic liability has not been demonstrated, until recently.

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Court Ruling Could Hamper Drug Innovation

March 4, 2009 11:58 am | by Linda A. Johnson, AP Business Writer | News | Comments

A US Supreme Court ruling that federal approval of a drug is no protection from lawsuits in state courts could make drugmakers more cautious about safety issues and may lead them to halt development of some medicines.

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Adventures in vivo

March 4, 2009 11:57 am | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | Comments

In vivo imaging technology developers and providers gear new features toward the drug discovery and development process.

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Saving Time and Sample

March 4, 2009 11:29 am | by David Hayes, Director, Research and Development, Bioscience Division, Millipore Corporation | Articles | Comments

Researchers step up to multiplex bead-based platforms to detect proteins for target indentification through clinical analysis.

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Helping Hands for Formulation

March 4, 2009 10:28 am | by Lindsay Hock, Associate Editor | Articles | Comments

With a push to help clients get into the clinic faster and get their drugs on the market, contract formulators assist in all stages of the drug formulation process.

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Genome Race Accelerates

March 4, 2009 9:39 am | by Rita C. Peters, Editor in Chief | Articles | Comments

It took 13 years and nearly $3 billion to sequence the first single human genome, a proverbial lifetime and bank bailout away from the goal of a $1000 genome for an individual’s DNA sequence.

Next Leg in hESC Race

March 4, 2009 9:23 am | by Ted Agres, Contributing Editor | Articles | Comments

The Food and Drug Administration’s (FDA) approval of a clinical trial involving a human embryonic stem cell-based therapy is being hailed both as a triumph of science over politics, as well as heralding a much-needed financial shot in the arm for the nascent hESC biotech industry.

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Contract Formulation Company Profile - Lyophilization Services of New England

March 4, 2009 8:28 am | Articles | Comments

Lyophilization Services of New England, Inc. (LSNE) has provided CGMP contract manufacturing services since 1997.

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The Blind Mole Rat: A Soldier in the War on Cancer

March 4, 2009 8:03 am | News | Comments

A new discovery shows that cellular mechanisms used by the blind mole rat to survive the very low oxygen environment of its subterranean niche are the same as those that tumors use to thrive deep in our tissues.

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Promising Target to Treat Chronic Abdominal Pain Uncovered

March 4, 2009 7:39 am | News | Comments

High levels of a protein linked to the way pain signals are sent to the brain led to a decrease in abdominal pain in a recent study in mice.

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