PharmaNet Development Group, Inc. has appointed George Scott, PhD, as vice president, Bioanalytical Services.
Shimadzu has integrated a low-pressure gradient (LPGE) unit to its Nexera ultra high-performance liquid chromatograph, allowing users to switch automatically between four mobile phases with solvent delivery units.
Thermo Fisher Scientific Inc. offers the EASY-nLC 1000 split-free nano-flow system that increases chromatographic resolution and protein and peptide identifications with high pressure operation.
Phenomenex Inc. has published a method for the analysis of aggregates of EPO, a recombinant biosimilar protein therapeutic. The gel filtration chromatography (GFC) method quantifies aggregates in recombinant therapeutics using a BioSep-SEC-s2000 series column, which provides a separation window for low-molecular-weight proteins.
LabLogic’s chromatography data system specifically for PET applications, Laura for PET can control and collect data generated by gas, thin-layer, and high pressure chromatography and multi-channel analysis.
Agilent Technologies Inc.’s Zorbax RRHD 300SB-C18 1.8 micron column for UHPLC systems is a silica reversed-phase column that can be used for higher-order reversed-phase characterization of intact proteins and protein digests.
Cardiotoxicity, which results when drugs adversely affect the heart, explains why roughly one-third of new pharmaceuticals are withdrawn from the market and why many compounds fail in late-stage clinical testing.
PerkinElmer offers screening assays for epigenetics that are built upon homogeneous assay platforms—LANCE Ultra detection assays for peptide substrates and AlphaLISA detection assays for peptide or full-length proteins.
Sigma Life Science’s CompoZr Targeted Integration Kit, mRosa26, can integrate transgenes into the mouse genome at the Rosa26 safe harbor locus.
EMD Millipore’s Magna ChIP-Seq preparation kit is designed to simplify genome-wide profiling of DNA-protein interactions by chromatin immunoprecipitation and next generation sequencing
Gardeners know that some trees require regular pruning: some branches must be cut so that others can grow stronger. The same is true of the developing brain: cells called microglia prune the connections between neurons, shaping how the brain is wired, scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, discovered.
Optimer Pharmaceuticals, Inc. launched Dificid (fidaxomicin) tablets for the treatment of Clostridium difficile-associated diarrhea (CDAD) in patients 18 years of age and older.
gIcare Pharma Inc. announced the closing of a $7 million Series A financing.
GenomeQuest and Pathogenica have announced a strategic partnership to offer discovery services in infectious disease research, including the interaction between the human microbiome and human genome.
A new study reveals that just as different soldiers in the field have different jobs, subsets of a type of immune cell that polices the barriers of the body can promote unique and opposite immune responses against the same type of infection.