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DDD Update

Daily news and top headlines for drug research professionals

Positive Results in Scar-Reducing Drug Trial

November 23, 2010 6:45 am | News | Comments

Renovo Group plc announced positive results in a clinical trial designed to establish the safety and efficacy of a new formulation of the scar revision drug Juvista intended for use in children.

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Vertex Submits Telaprevir NDA

November 23, 2010 6:40 am | News | Comments

Vertex Pharmaceuticals Incorporated has completed the submission of a new drug application to the U.S. Food and Drug Administration seeking approval for telaprevir, Vertex's investigational treatment for people with hepatitis C.

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Antiplatelet Mix Raises Risk of Bleeding

November 23, 2010 6:29 am | News | Comments

Dual antiplatelet therapy—treatment with the medications clopidogrel and aspirin together to prevent blood clots—poses a clinically significant risk of hemorrhage that should be considered before prescribing.

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Heat Destroys Drug-Resistant Bacteria

November 23, 2010 6:27 am | News | Comments

New findings by civil engineering researchers show that treating municipal wastewater solids at higher temperatures may be an effective tool in the fight against antibiotic-resistant bacteria.

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HIV Drugs Lead to Diabetes

November 23, 2010 6:25 am | News | Comments

The same powerful drugs that have extended the lives of countless people with HIV come with a price – insulin resistance that can lead to diabetes and cardiovascular disease.

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Spinal Cord Growth Controllable

November 23, 2010 6:23 am | News | Comments

Both the rate and direction of axon growth in the spinal cord can be controlled. A series of connections at the cellular level produce a guidance cue that tells an axon how fast and in which direction to grow in an embryonic environment.

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New Approach to Lou Gehrig's Disease

November 23, 2010 6:20 am | News | Comments

Amyotrophic lateral sclerosis is a fatal neurodegenerative disease that eventually destroys most motor neurons, causing muscle weakness and atrophy throughout the body. There is no cure and the current treatment has only a moderate effect on the disease.

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Treatment Delays Costly in HIV

November 23, 2010 6:17 am | News | Comments

HIV infected patients whose treatment is delayed not only become sicker than those treated earlier, but also require tens of thousands of dollars more in care over the first several years of their treatment.

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Half of Depression Suffers Stop Meds

November 23, 2010 6:16 am | News | Comments

Most patients who take anti-depressants give up their treatment in less than six months, the minimum period recommended for treating severe depression and only 25% continue their treatment for more than 11 months.

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New Tool in Fight Against Ebola

November 23, 2010 6:13 am | News | Comments

Boston University researchers have developed a simple diagnostic tool that can quickly identify dangerous viruses like Ebola and Marburg. The biosensor is the size of a quarter and can detect viruses in a blood sample.

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Gene Protects Cancer from Chemo

November 23, 2010 6:12 am | News | Comments

Researchers at Virginia Commonwealth University have discovered that a gene well known for its involvement in tumor cell development, growth and metastasis also protects cancer cells from being destroyed by chemotherapy.

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3D Cell Culture

November 22, 2010 7:49 am | Drug Discovery & Development | Product Releases | Comments

Reinnervate has announced the first commercial launch of alvetex, its 3D cell culture technology. Alvetex provides a robust and inert scaffold for cells to grow and form complex 3D cell structures, mimicking the normal growth and formation of tissues.

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Recirculating Chillers

November 22, 2010 7:43 am | Product Releases | Comments

Thermo Fisher Scientific Inc. has introduced the ThermoChill I and ThermoChill II re-circulating chillers. These compact, floor-standing re-circulating chillers provide a temperature range of 5 to 30°C and have a cooling capacity from 700 to 2000 W.

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Rare Disease Reveals Path to Stem Cells

November 22, 2010 7:35 am | News | Comments

Researchers at Harvard Medical School and the Harvard School of Dental Medicine have found that by mimicking a rare genetic disorder in a dish, they can rewind the internal clock of a mature cell and drive it back into an adult stem-cell stage.

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Normal Tissue Turned Into 3D Cancer

November 22, 2010 7:31 am | News | Comments

Researchers have successfully transformed normal human tissue into three-dimensional cancers in a tissue culture dish for the first time. Watching how the cells behave as they divide and invade surrounding tissue will help physicians better understand how human cancers act in the body.

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