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DDD Update

Daily news and top headlines for drug research professionals

BMS Board Authorizes $3B Stock Buyback

May 4, 2010 7:23 am | News | Comments

Bristol-Myers Squibb Company announced its Board of Directors has authorized the repurchase of up to $3 billion of its common stock.


Broccoli Component Limits Breast Cancer Stem Cells

May 4, 2010 7:08 am | News | Comments

A compound derived from broccoli could help prevent or treat breast cancer by targeting cancer stem cells--the small number of cells that fuel a tumor's growth--according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.


Signaling Pathways May Link Cancer and Neurodegeneration

May 4, 2010 6:59 am | News | Comments

At first glance, cancer and neurodegenerative diseases seem to have little in common, but the more that is learned about the signaling pathways that control cell division, differentiation, neuronal plasticity and cell death, the more apparent is the overlap between the two types of disease.


CS-8635 Shows Greater Reduction in Blood Pressure

May 4, 2010 6:48 am | News | Comments

Currently under FDA review, CS-8635 combines three powerful blood pressure treatments with different mechanisms of action, Benicar (olmesartan medoxomil), amlodipine and hydrochlorothiazide.


Cempra Announces TAKSTA Phase 2 Results

May 4, 2010 6:35 am | News | Comments

Cempra Pharmaceuticals announced positive results from its Phase 2 clinical trial evaluating the efficacy and tolerability of the novel front loading dosing regimen of TAKSTA, the company’s oral, anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotic.


FDA Probes Prostate Cancer Drugs

May 4, 2010 6:24 am | News | Comments

The Food and Drug Administration is looking into data suggesting a group of prostate cancer drugs increase the risk of diabetes and heart disease.


Lawsuit Filed Against Merck Over Gardasil

May 4, 2010 6:20 am | News | Comments

An Albuquerque woman has filed a lawsuit over a vaccine intended to protect women from cervical cancer, alleging it caused physical and behavioral problems in her teenage daughter.


Gilead to Submit NDA for Combination Truvada-TMC278

May 4, 2010 6:10 am | News | Comments

Gilead Sciences, Inc. has obtained data supporting bioequivalence of a formulation of the fixed-dose combination of Truvada and Tibotec Pharmaceuticals' investigational non-nucleoside reverse transcriptase inhibitor TMC278.


Spectroscopy Software

May 3, 2010 8:04 am | Product Releases | Comments

Thermo Fisher Scientific Inc. announced the latest release in its GRAMS Suite of spectroscopy software, an industry standard solution for visualizing, processing, reporting and managing spectroscopy data.


xCELLigence Useful for Testing Cytotoxicity

May 3, 2010 7:54 am | Product Releases | Comments

Monitoring of cell viability and toxicity are critical to many areas of biological and biomedical research. This is true for understanding the molecular and biochemical pathways regulating cell viability, for developing therapeutic agents which modulate cell viability and for identifying potential cytotoxic side effects of potential therapeutic agents.


Indiana Researchers Find Inflammatory Trigger

May 3, 2010 7:43 am | News | Comments

Researchers at Indiana University School of Medicine have identified a mechanism that causes inflammation in asthma and other allergic diseases, a discovery that could lead to new targets to control such allergic reactions.


CFSE T Cell Proliferation Assays

May 3, 2010 7:17 am | Product Releases | Comments

ProImmune Ltd offers the CFSE T cell proliferation assays for immunogenicity risk assessment used in the design and selection of biological drug leads at the preclinical stage.


BrainCells Issued First Patent for Neurogenic Drug Combinations

May 3, 2010 7:08 am | News | Comments

BrainCells Inc. announced that the United States Patent and Trademark Office issued the company Patent Number 7,678,808 entitled, “5 HT Receptor Mediated Neurogenesis.”


TB Alliance Collaborating With AstraZeneca

May 3, 2010 7:02 am | News | Comments

The Global Alliance for TB Drug Development (TB Alliance) and AstraZeneca announced at the 2010 BIO International Convention that they have entered into a research collaboration agreement to accelerate the discovery, development and clinical use of drugs against tuberculosis (TB), including drug-resistant strains of the disease.


Advanced Mycoplasma Tests

May 3, 2010 7:02 am | Product Releases | Comments

A new white paper, “Advanced Detection of Mycoplasmas: How Real-Time PCR Analysis Helps Save Time and Money for Biopharmaceutical Manufacturers,” explores relevant mycoplasma characteristics, established testing solutions, and the use of real-time PCR analysis as an alternative testing method for fast, preliminary mycoplasma detection.



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