Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, a team of scientists has produced the first-ever epigenetic landscape map for tissue differentiation.
A new study describes how a carbohydrate-binding protein, galectin-3, promotes angiogenesis, the growth of new blood vessels. Targeting the protein, scientists identified two approaches that significantly reduced angiogenesis in mice.
Pfizer Inc. announced that the U.S. Food and Drug Administration has granted approval of the use of a Prefilled Dual-Chamber Syringe for administration of XYNTHA Antihemophilic Factor (Recombinant) Plasma/Albumin-Free to hemophilia A patients.
Federal health scientists are questioning whether the antidepressant Cymbalta is safe and effective enough to be approved for use against chronic pain.
Federal health regulators are pushing to withdraw a blood pressure drug that has been on the market for 14 years in spite of the manufacturer's failure to submit evidence that it actually helps patients.
Warren Buffett's Berkshire Hathaway Inc. has partially rebuilt the stake in Johnson & Johnson he reduced over the past two years to raise cash for other investments.
Drugmaker Eli Lilly and Co. has stopped developing a potential Alzheimer's disease treatment in late-stage testing after patients taking the drug fared worse than those on a placebo.
CER-001 is an experimental high-density lipoproteins mimetic being developed by Cerenis Therapeutics. This class of drugs removes cholesterol from the vessel wall to treat high-risk atherosclerosis, including acute coronary syndrome.
In recent years, treatment strategies for type 2 diabetes have been focused on the development of novel therapeutic options, especially new drugs targeting the incretin system.
Biotage, a leading developer of tools and technology for medicinal and analytical chemistry, announces the introduction of the Isolera UV-VIS flash purification system.
Sage-N Research Inc., a leader in computational proteomics, announces the integration of the first commercially available phosphorylation tool using mass spectrometry into its drug discovery platform.
Researchers at North Carolina State University have developed a method for predicting the ways nanoparticles will interact with biological systems – including the human body.
Once thought to be a problem primarily in the developed world, cancer is now a leading cause of death and disability in poorer countries. Almost two-thirds of the 7.6 million cancer deaths in the world occur in low- and middle-income countries.
Pharmacy benefits manager Medco Health Solutions Inc. said it will buy United BioSource Corp., which develops technology used in clinical trials and patient monitoring, for $730 million in cash.
Amgen announced top-line results from a randomized Phase 3 trial evaluating Vectibix as a first-line treatment in patients with recurrent and/or metastatic squamous cell head and neck cancer.