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DDD Update

Daily news and top headlines for drug research professionals

Gene Affecting Clopidogrel Not Issue With Ticagrelor

August 31, 2010 8:19 am | News | Comments

A substudy of PLATO showed that the effects of ticagrelor on acute coronary syndrome patients who received the investigational oral antiplatelet treatment were maintained, whether or not they had the genetic variability that has been previously shown to affect a patient’s response to clopidogrel.

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Trius Begins Phase 3 Antibiotic Trial

August 31, 2010 8:09 am | News | Comments

Trius Therapeutics, Inc. announced that the first patient has been dosed in its Phase 3 clinical study of the oral dosage form of torezolid phosphate for the treatment of acute bacterial skin and skin structure infections.

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Amino Acid Vital to Fight Against Infection

August 31, 2010 7:24 am | News | Comments

Two University of Alberta researchers may be able to explain why proper nutrition is so vital in fighting infection. They have discovered an amino acid, called arginine, is required to let the body know that it's being attacked by an infection.

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Structural Defects Precede Decline In Heart Muscle

August 31, 2010 7:20 am | News | Comments

The disruption of a structural component in heart muscle cells, which is associated with heart failure, appears to occur even before heart function starts to decline, according to a new study.

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Nearby Cancer Cells Could Help Spread Melanoma

August 31, 2010 6:59 am | News | Comments

New research on how skin cancer begins has identified adjacent cancer cells that scientists are calling "co-conspirators" in the genesis of melanoma, findings that could someday allow the prediction, prevention, and treatment of this hard-to-treat cancer.

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Research Shows How Trypanosomes Evade Immune System

August 31, 2010 6:54 am | News | Comments

Trypanosomes are parasites responsible for many deaths, primarily in tropical climates. A team of researchers has shown, for the first time, how one such species evades the human innate defenses. The finding could open the way for new classes of drugs to treat the epidemic.

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Study Demonstrates Benefits of Cannabis for Pain

August 31, 2010 6:47 am | News | Comments

The medicinal use of cannabis has been debated by clinicians, researchers, legislators and the public at large for many years. A new study provides evidence that cannabis may offer relief to patients suffering from chronic neuropathic pain.

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Decongestant Use Linked to Fewer Premature Babies

August 31, 2010 6:44 am | News | Comments

A new study has found that women who took over-the-counter decongestants during their pregnancies are less likely to give birth prematurely. Preterm birth is the leading cause of infant morbidity and mortality in developed countries.

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New Device Allows Better Neutrophil Collection

August 31, 2010 6:40 am | News | Comments

A group of scientists has developed a microfluidic tool for quickly and accurately isolating neutrophils from small blood samples, an accomplishment that could provide information essential to better understanding the immune system's response to traumatic injury.

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Researchers to Activate Anti-Cancer Gene

August 31, 2010 6:34 am | News | Comments

The lining of the gut is coated in epithelial cells, a specialised layer that keeps dangerous bacteria and toxins at bay. Close contact with pathogenic microbes and toxins means that the epithelial cells may mutate to form cancer.

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A New Approach to Gene Splicing

August 31, 2010 6:30 am | News | Comments

A team of researchers has developed a type of hybrid proteins that can make double-strand DNA breaks at specific sites in living cells, possibly leading to better gene replacement and gene editing therapies.

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Divisible PCR Plates

August 30, 2010 8:46 am | Drug Discovery & Development | Product Releases | Comments

Eppendorf offers the first two-component PCR plate designed to be easily divisible. These twin.tec unskirted 96-well plates fit almost all available PCR instruments and can be snapped into four separate 24-well segments

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Tube Auditor Software

August 30, 2010 8:40 am | Product Releases | Comments

RTS Life Science, a worldwide supplier of automated sample management and pharmaceutical testing systems, has added a series of new software features to the RTS Tube Auditor.

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Protein Tied to Severe Allergic Asthma

August 30, 2010 8:16 am | News | Comments

Scientists have identified a genetic basis for determining the severity of allergic asthma in experimental models of the disease.

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Genetic Link Between Migraine Sufferers Found

August 30, 2010 8:14 am | News | Comments

After looking at the genetic data of more than 50,000 people, a world-wide collaboration of researchers has identified the first-ever genetic risk factor associated with common types of migraine.

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