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DDD Update

Daily news and top headlines for drug research professionals

Trevigen Receives Grant for Cell Line Panel

October 27, 2010 8:08 am | News | Comments

Trevigen, Inc., a leader in providing specialized products for the study of DNA damage and cancer cell behavior, announced that it is the primary recipient of a NIGMS, two-year Phase 2 Grant for $2,526,726.


Pharmaxis Announces Phase 3 Data

October 27, 2010 8:03 am | News | Comments

Pharmaceutical company Pharmaxis announced significant results of pooled data from its two large scale six month Phase 3 trials of Bronchitol (inhaled mannitol) in people with cystic fibrosis.


Nymox BPH Drug in Phase 3 Trials

October 27, 2010 7:59 am | News | Comments

Nymox Pharmaceutical Corporation provided an update on the company's Phase 3 pivotal trials for NX-1207, Nymox's investigational drug for benign prostatic hyperplasia. The Safety Monitoring Committee meeting was favorable and indicated no significant safety concerns.


FDA Tells BMS to Fix Puerto Rico Plant

October 27, 2010 7:46 am | by Linda A. Johnson | News | Comments

U.S. regulators have told drugmaker Bristol-Myers Squibb Co. they won't approve an important new drug until the company fixes multiple deficiencies at its Puerto Rico manufacturing plant, the company's CEO has disclosed.


GSK Settles $750M Adulterated Drug Suit

October 27, 2010 7:41 am | by Denise Lavoie | News | Comments

British pharmaceutical company GlaxoSmithKline PLC will pay $750 million to settle allegations that it knowingly manufactured and sold adulterated drugs, including the popular antidepressant Paxil, federal prosecutors in Massachusetts said.


Database Launched to Personal Cancer Treatment

October 27, 2010 7:27 am | News | Comments

An overall goal of the Georgetown Database of Cancer is to accelerate the personalization of medical treatment for patients. G-DOC means that physicians and researchers need only access a single website to open a universe of information on cancer.


Cetuximab May Work for Some Colorectal Cancer Patients

October 27, 2010 7:23 am | News | Comments

Research indicates that patients with a variant of KRAS-mutated metastatic colorectal tumors who don't respond to chemotherapy and were treated with cetuximab had longer overall and progression-free survival than patients with other KRAS-mutations.


Reaction to Sleep Deprivation May Be Genetic

October 27, 2010 7:15 am | News | Comments

A study looked at people who have a gene variant that is closely associated with narcolepsy, a sleep disorder that causes excessive daytime sleepiness. However, having the gene variant, called DQB1 *0602, does not mean that a person will develop narcolepsy.


Gene Variants Lead to Worse Outcome with Clopidogrel

October 27, 2010 7:08 am | News | Comments

New analysis indicates that use of clopidogrel in patients who have common genetic variants of a certain gene and are undergoing a procedure such as coronary stent placement have an associated increased risk for major adverse cardiovascular events.


Study Identifies Key Molecules in Multiple Myeloma

October 27, 2010 7:04 am | News | Comments

New research links three molecules to a critical tumor suppressor gene that is often turned off in multiple myeloma, a presently incurable cancer of the blood. The findings might offer a new strategy for treating this disease and other blood cancers.


Haptoglobin Biomarker for Virus-induced Diabetes

October 27, 2010 7:00 am | News | Comments

In addition to genetic susceptibility, it is generally accepted that environmental factors play important roles in triggering Type 1 diabetes, with virus infection having perhaps the strongest association.


New Research Says lncRNA Affects Immune Response

October 27, 2010 6:56 am | News | Comments

Scientists have demonstrated for the first time that long non-protein-coding RNA (lncRNA) are involved in the host response to viral infection. These findings could greatly change the way scientists look at the body's response to viral infection.


Widefield Fluorescence System

October 26, 2010 8:17 am | Product Releases | Comments

Leica Microsystems has extended its automated high-content screening solution to cover applications on widefield fluorescence systems. The Leica HCS A package enables fast and efficient multi-position experiments.


Bisulfite Conversion Kit

October 26, 2010 8:11 am | Product Releases | Comments

EMD Millipore, the life science division of Merck KGaA of Germany, announced the introduction of a rapid kit for bisulfite conversion, which is a critical first step in mapping the differences in genomic DNA methylation patterns.


Celtic And Resolvyx Sign Deal for RX-10045

October 26, 2010 8:02 am | News | Comments

Celtic Therapeutics Holdings L.P. and Resolvyx Pharmaceuticals, Inc. announced that they have entered into an option agreement relating to Resolvyx’s RX-10045, a late-stage program for the treatment of dry eye syndrome and other ophthalmic conditions.



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