U.S. regulators have told drugmaker Bristol-Myers Squibb Co. they won't approve an important new drug until the company fixes multiple deficiencies at its Puerto Rico manufacturing plant, the company's CEO has disclosed.
British pharmaceutical company GlaxoSmithKline PLC will pay $750 million to settle allegations that it knowingly manufactured and sold adulterated drugs, including the popular antidepressant Paxil, federal prosecutors in Massachusetts said.
An overall goal of the Georgetown Database of Cancer is to accelerate the personalization of medical treatment for patients. G-DOC means that physicians and researchers need only access a single website to open a universe of information on cancer.
Research indicates that patients with a variant of KRAS-mutated metastatic colorectal tumors who don't respond to chemotherapy and were treated with cetuximab had longer overall and progression-free survival than patients with other KRAS-mutations.
A study looked at people who have a gene variant that is closely associated with narcolepsy, a sleep disorder that causes excessive daytime sleepiness. However, having the gene variant, called DQB1 *0602, does not mean that a person will develop narcolepsy.
New analysis indicates that use of clopidogrel in patients who have common genetic variants of a certain gene and are undergoing a procedure such as coronary stent placement have an associated increased risk for major adverse cardiovascular events.
New research links three molecules to a critical tumor suppressor gene that is often turned off in multiple myeloma, a presently incurable cancer of the blood. The findings might offer a new strategy for treating this disease and other blood cancers.
In addition to genetic susceptibility, it is generally accepted that environmental factors play important roles in triggering Type 1 diabetes, with virus infection having perhaps the strongest association.
Scientists have demonstrated for the first time that long non-protein-coding RNA (lncRNA) are involved in the host response to viral infection. These findings could greatly change the way scientists look at the body's response to viral infection.
Leica Microsystems has extended its automated high-content screening solution to cover applications on widefield fluorescence systems. The Leica HCS A package enables fast and efficient multi-position experiments.
EMD Millipore, the life science division of Merck KGaA of Germany, announced the introduction of a rapid kit for bisulfite conversion, which is a critical first step in mapping the differences in genomic DNA methylation patterns.
Celtic Therapeutics Holdings L.P. and Resolvyx Pharmaceuticals, Inc. announced that they have entered into an option agreement relating to Resolvyx’s RX-10045, a late-stage program for the treatment of dry eye syndrome and other ophthalmic conditions.
Techulon Inc. has signed an exclusive license with Virginia Tech Intellectual Properties Inc. to market a new, traceable DNA delivery platform created to deliver genetic medicine to cells while carrying a beacon so scientists can follow its progress.
When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called splicing.
A popular cancer drug could be produced cheaply and sustainably using stem cells derived from trees, a study suggests. Researchers have isolated and grown stem cells from a yew tree whose bark is a natural source of the drug paclitaxel.