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DDD Update

Daily news and top headlines for drug research professionals

Phenomenex And Shimadzu in Chromatography Collaboration

February 23, 2011 5:51 am | News | Comments

Phenomenex Inc. and Shimadzu Scientific Instruments announced a marketing collaboration for LC and GC systems. Through this collaboration, Shimadzu systems and Phenomenex columns will be offered together as a complete solution.

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Search Identifies Potential Brain Disease Drug

February 23, 2011 5:42 am | News | Comments

Scientists who examined more than 10,000 chemical compounds during the last year in search of potential new drugs for a group of untreatable brain diseases, are reporting that one substance shows unusual promise.

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USPTO Awards New Patent to Somaxon

February 23, 2011 5:37 am | News | Comments

Somaxon Pharmaceuticals Inc. said it received a new patent on its insomnia drug Silenor, extending its exclusivity on the drug. The company said the U.S. Patent and Trademark Office awarded it a patent that will expire no earlier than July 2027.

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Delcath Takes Hit After FDA Refusal

February 23, 2011 5:16 am | News | Comments

Delcath Systems Inc. is reeling after the company said regulators did not accept a marketing application for its cancer therapy system. The Food and Drug Administration refused to file Delcath's application for its chemotherapy system.

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SIGA On Track for Billion-Dollar Smallpox Contract

February 23, 2011 5:14 am | News | Comments

Shares of biodefense company SIGA Technologies Inc. rose sharply after government actions signaled that the company is a top contender to supply millions of doses of smallpox treatment for a national stockpile.

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Vertex Drug Improves Lung Function

February 23, 2011 5:09 am | News | Comments

Vertex Pharmaceuticals Inc. said that its potential cystic fibrosis drug improved lung function in a key late-stage study. The company said VX-770 prompted a 10.5 percent improvement in lung function.

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Non-radioactive Homogeneous Assays for Detecting Histone Epigenetic Modifications

February 23, 2011 4:55 am | by Roberto Rodriguez-Suarez, PhD, Senior Scientist; Lucille Beaudet, PhD, Senior Project Leader; Nathalie Rouleau, Section Leader Research & Development, Bio-discovery Division; PerkinElmer BioSignal, Montreal, Canada | Articles | Comments

The expression of the thousands of genes present in the human cell is regulated in good part by dynamic changes in chromatin compaction throughout the different regions of the genome.

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Managing the Dose: The VASP Assay for Anti-P2Y12 Drugs

February 23, 2011 4:49 am | by Paul Riley, PhD, Product Manager; Diagnostica Stago, Inc., Parsippany, N.J. | News | Comments

In a clinical trial, the selection of an appropriate dose of a drug leads to optimal efficacy and safety as the trial progresses. By necessity, assays are developed that specifically measure responsiveness to a drug.

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Cancer Cell Lines

February 22, 2011 7:14 am | Product Releases | Comments

Sigma Life Science, the biological products and services research business of Sigma-Aldrich, announced the addition of genetically modified cancer cells to the company’s range of cell lines.

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Large-Scale Flow Chemistry

February 22, 2011 7:07 am | Drug Discovery & Development | Product Releases | Comments

Uniqsis has launched the first instrument on the market for multi-kilogram flow chemistry. FlowSyn MAXI, allows users to safely perform larger-scale flow reactions, at up to 100ml/min between –90ºC and 260ºC, and at pressures up to 1400 psi.

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Supreme Court Tosses Vaccine Lawsuit

February 22, 2011 6:55 am | by Mark Sherman | News | Comments

The Supreme Court ruled that a federal law bars lawsuits against drug makers over serious side effects from childhood vaccines. By a 6-2 vote, the court ruled against the parents of a child who sued Wyeth for the health problems they say their daughter suffered.

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FDA Approves Generic Adoxa

February 22, 2011 6:50 am | News | Comments

Impax Laboratories Inc. said it received Food and Drug Administration approval for a generic version of 150-milligram capsules of the antibiotic Adoxa, which is used to treat bacterial infections.

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Frost & Sullivan Awards Carestream Molecular Imaging

February 22, 2011 6:47 am | News | Comments

Based on its recent analysis of the preclinical imaging systems market, Frost & Sullivan recognizes Carestream Molecular Imaging with the prestigious 2011 Frost & Sullivan Best Practice Award for Preclinical Imaging Systems Product Line Strategy.

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Fungus Takes Aim at Malaria Hosts

February 22, 2011 6:42 am | News | Comments

In 2009, malaria was responsible for 781,000 deaths worldwide. New research presents a method of dispersing pathogenic fungi as a means of preventing the spread of malaria.

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Scientists Link Amphetamines to Parkinson's

February 22, 2011 6:39 am | News | Comments

New research shows people who have used amphetamines such as benzedrine and dexedrine appear to be at an increased risk of developing Parkinson's disease.

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