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DDD Update

Daily news and top headlines for drug research professionals

GSK Announces Singapore Collaborations

October 7, 2010 8:11 am | News | Comments

GlaxoSmithKline R&D announced the start of four new academic collaborations with Singapore-based scientists and GSK’s global drug discovery network as the first step in a longer term plan to seek alliances with scientific experts in the country.

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Insoluble Nanodrugs Can Still Be Absorbed

October 7, 2010 8:08 am | News | Comments

Researchers in India have demonstrated that producing nanoscopic crystals of a pharmaceutical product can allow the medication to be absorbed by the gut even if the drug is not soluble in water.

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Zebrafish Tumors Similar to Humans

October 7, 2010 8:00 am | News | Comments

While human cells have 23 pairs of chromosomes, tumor cells usually have extra copies of some chromosomes. This trait, known as aneuploidy, appears to give tumor cells a survival edge.

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FDA Admits Need to Modernize

October 7, 2010 7:55 am | by Matthew Perrone | News | Comments

The Food and Drug Administration must update its scientific tools for reviewing prescription drugs, medical devices and tracking food safety, according to a research plan laid out by agency leadership.

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Prescription Drug Sales May Increase 7%

October 7, 2010 7:53 am | by Linda A. Johnson | News | Comments

Revenue from global prescription drug sales should increase 5 percent to 7 percent next year, reaching at least $880 billion, fueled by new drugs and rising sales in developing countries, according to drug data firm IMS Health.

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Rituximab Shows Benefits in Untreated CLL

October 7, 2010 7:46 am | News | Comments

The monoclonal antibody rituximab given in addition to a standard chemotherapy regimen of fludarabine plus cyclophosphamide significantly prolongs the lives of patients with chronic lymphocytic leukaemia compared with standard chemotherapy alone.

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Sanofi Publishes Jevtana Data

October 7, 2010 7:41 am | News | Comments

The data demonstrated that Jevtana with prednisone reduced the risk of death by 30% in men with metastatic castration-resistant prostate cancer whose disease progressed following treatment with a docetaxel-containing treatment regimen.

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Amgen Announces Results of Phase 3 Studies

October 7, 2010 7:36 am | News | Comments

Amgen announced that results from the PRIME '203' and '181' pivotal Phase 3 trials evaluating Vectibix in combination with chemotherapy (FOLFOX or FOLFIRI) as a first and second-line treatment for metastatic colorectal cancer, respectively.

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ISTA Announces Positive Results of Allergy Study

October 7, 2010 7:29 am | News | Comments

ISTA Pharmaceuticals, Inc. announced positive preliminary results from a Phase 1/2 clinical study of bepotastine besilate nasal spray for the treatment of symptoms associated with seasonal allergic rhinitis, the inflammation of the nasal passages caused by allergies.

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Immunocore Melanoma Drug Receives Trial OK

October 7, 2010 7:24 am | News | Comments

Researchers at Immunocore Limited announced that IMCgp100, a targeted therapeutic for the treatment of advanced metastatic melanoma, has received regulatory and ethics approval and has opened enrollment for clinical trials in the UK and USA.

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NephRx Drug Helps Mucositis Sufferers

October 7, 2010 7:18 am | News | Comments

NephRx Corporation announced that a study has shown that its peptide NX002 demonstrated significant efficacy when tested in an animal model of oral mucositis. Mucositis is a debilitating and often dose-limiting side effect of many forms of cancer therapy.

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Unexpected Results from Gene Therapy Trial

October 7, 2010 7:11 am | News | Comments

A clinical trial designed to replace the genetic defect causing the most common form of muscular dystrophy has discovered that some patients mount an immune response to the dystrophin protein even before they have received the gene therapy.

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3D Tissue Construction

October 6, 2010 8:52 am | Product Releases | Comments

The Automation Partnership (TAP) has announced RAFT (Real Architecture for 3D Tissue), its system for generating reproducible, 3D collagen tissue constructs.

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BME-Dependent Cell Invasion Assay

October 6, 2010 8:49 am | Product Releases | Comments

Combining research on factors affecting BME-dependent cell invasion assay performance with the advantages of offering the assay in a format where the BME is already coated on the invasion plate, the 96 well CultreCoat optimized BME cell invasion assay was designed.

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Thermal Cyclers

October 6, 2010 8:29 am | Product Releases | Comments

Thermo Fisher Scientific Inc. has introduced the Piko and Arktik Thermal Cyclers. These two Thermo Fisher Scientific PCR instruments meet the needs of a broad range of researchers, for applications covering individual PCRs through to high throughput projects.

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