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DDD Update

Daily news and top headlines for drug research professionals

Debiopharm, Aurigene Collaborate on Debio 1142

May 5, 2011 8:29 am | News | Comments

Debiopharm Group and Aurigene Discovery Technologies signed an agreement concerning the development and commercialization of Debio 1142, a novel inhibitor of an undisclosed oncology pathway.

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Celldex Loss Widens on Revenue Dip

May 5, 2011 8:23 am | News | Comments

Cancer drug developer Celldex Therapeutics Inc. reported a larger first-quarter loss, saying its revenue and investment income decreased. Celldex lost $10.1 million, or 31 cents per share.

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Par Bottom Line Stung By $196M Settlement

May 5, 2011 8:19 am | News | Comments

Par Pharmaceutical posted a first-quarter loss following a quarter in which the generic drug developer saw sales of a key drug slide and also a hefty legal charge.

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J & J Ending Run of Infant Acetaminophen Drops

May 5, 2011 8:16 am | News | Comments

Johnson & Johnson and other makers of cold and fever medications said that they will discontinue infant drops of medicines containing acetaminophen in an effort to avoid confusion that can lead to dangerous overdoses.

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Supreme Court Grants Viagra Appeal

May 5, 2011 8:12 am | News | Comments

The Supreme Court will hear a Canadian drug maker's challenge of the Viagra patent held by pharmaceutical giant Pfizer. The high court granted the leave to appeal that was being sought by Teva Canada.

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Eli Lilly Molecules Target Genetic Mutations

May 5, 2011 8:09 am | News | Comments

Eli Lilly and Company announced results from two preclinical studies of molecules that target genetic mutations and disable specific signaling pathways that can lead to cancer.

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Algeta Licenses Affibody Molecules

May 5, 2011 8:04 am | News | Comments

Algeta has entered a research, development, and commercialization agreement with Affibody to develop tumor-targeting alpha-pharmaceuticals based on thorium-227.

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Argos: Immunotherapy Platform Shows Promise

May 5, 2011 7:59 am | News | Comments

Argos Therapeutics announced that an immunotherapy platform based on recombinant human soluble CD83 demonstrated significant promise for renal and heart transplantation.

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White Blood Cells Stop Treatment

May 5, 2011 7:52 am | News | Comments

Cancer Research UK scientists discovered tumors can recruit part of the body’s defense system to protect them from the effect of a drug designed to block the supply of blood to the tumor.

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An N-type Calcium Channel Blocker for Chronic Pain

May 5, 2011 7:49 am | by Simon Tate, Chief Scientific Officer; Convergence Pharmaceuticals Ltd, Cambridge, U.K. | Articles | Comments

The drug discovery and development community is faced with an immense challenge, as it moves to bring novel analgesic medicines, with an improvement in efficacy, responder rate, and safety to the market.

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Nycomed and Almirall Co-brand Roflumilast

May 5, 2011 7:49 am | News | Comments

Nycomed and Almirall have entered a co-branding agreement for the commercialization in Spain of Roflumilast, a once-daily tablet for patients with chronic obstructive pulmonary disease (COPD).

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Private TB Drug Market Worries Officials

May 5, 2011 7:44 am | News | Comments

Tuberculosis (TB) is widely considered a public health concern and its treatment a public sector responsibility; however, the private sector aspect for its treatment is ignored.

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Study Reveals TA-65 Behavior

May 5, 2011 7:30 am | News | Comments

A study, “The Telomerase Activator TA-65 elongates short telomeres and increases healthspan of adult/old mice without increasing cancer incidence” describes TA-65’s mechanism of action and organismal response.

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Protein May Control Weight Gain

May 5, 2011 6:24 am | News | Comments

Scientists have added another piece to the obesity puzzle, showing how and why a certain protein that is active in a small part of the brain contributes to weight gain.

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Protein Could Help Prevent Spread of Cancer

May 5, 2011 6:20 am | News | Comments

A protein capable of halting the spread of breast cancer cells could lead to a therapy for preventing or limiting the spread of the disease.

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