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DDD Update

Daily news and top headlines for drug research professionals

CoDa Releases Positive Results From Phase 2 Study

July 9, 2010 7:23 am | News | Comments

CoDa Therapeutics, Inc. announced positive results from its Phase 2 NOVEL Study of NEXAGON in patients with chronic venous leg ulcers.

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BOTOX Licensed to Treat Chronic Migraine

July 9, 2010 7:18 am | News | Comments

Allergan has announced that BOTOX (botulinum toxin type A) has been licensed by the MHRA in the UK for the prophylaxis of headaches in adults who have chronic migraine—headaches on at least 15 days per month of which at least 8 days are with migraine.

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Cancer Stem Cells Vary From Tumor to Tumor

July 9, 2010 7:07 am | News | Comments

Cancer stem cells have enticed scientists because of the potential to provide more durable and widespread cancer cures by identifying and targeting the tumor’s most voracious cells.

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GSK Diabetes Drug Target of Exhaustive FDA Review

July 9, 2010 7:02 am | by Matthew Perrone | News | Comments

A review by federal health scientists reinforces potential ties between the diabetes pill Avandia and heart attack and death, opening the door for government action, including a possible withdrawal of the once blockbuster drug.

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Newly Discovered Antibodies Stop Most HIV Strains

July 9, 2010 6:27 am | News | Comments

Scientists have discovered two potent human antibodies that can stop more than 90% of known global HIV strains from infecting human cells in the laboratory, possibly leading to improved vaccines to prevent or treat HIV infection.

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Sales Crumble Amidst New Recall

July 9, 2010 6:15 am | News | Comments

Sales of Johnson & Johnson pain relievers are collapsing as a string of recalls appears to have made consumers wary of once-sterling brands such as Tylenol and Motrin.

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EMEA Reviewing Safety of Avandia

July 9, 2010 6:02 am | News | Comments

The European agency that evaluates medicine said it will review the safety of the diabetes drug Avandia following research suggesting it is linked to a higher risk of heart problems, strokes and deaths in older adults.

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Fluorescence Imaging of Cranial Vasculature in Live Animals

July 8, 2010 10:32 am | by Deepak Sharma, PhD, Senior Product Manager, Photometrics, Tuscon, Ariz. | Articles | Comments

Radiation therapy is one of the most successful treatments for malignant tumors. In addition to causing tumor death it also weakens and collapses the rapidly forming vasculature around the tumor.

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ADRCs for Tissue Reconstruction in Cancer

July 8, 2010 10:18 am | by Ning Zhang PhD, Senior Project Leader, Caliper Life Sciences, Hopkinton, Mass. | Articles | Comments

Regenerative medicine is a rapidly emerging field using stem cells to repair or restore function to tissues lost or damaged due to the effects of injury, disease, and aging.

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Extraction Kit

July 8, 2010 8:22 am | Product Releases | Comments

Beckman Coulter Genomics has announced the development of a new version of the DNAdvance System for use with DNA Genotek’s Oragene•DNA samples.

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Merck Shuttering Sixteen Sites Worldwide

July 8, 2010 8:16 am | by Linda A. Johnson | News | Comments

Drugmaker Merck & Co. said it is shutting down eight manufacturing plants and eight research sites around the world, including two domestic locations, in the latest phase in its strategic pruning of operations.

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Liquid Handler

July 8, 2010 8:12 am | Product Releases | Comments

The mosquito LCP liquid handler from TTP LabTech has been designed to facilitate the crystallisation of membrane proteins, such as G-protein coupled receptors, by offering a fully automated solution to lipid cubic phase screening.

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MorphoSys Receives Grant From German Government

July 8, 2010 8:01 am | News | Comments

MorphoSys AG announced that it has been awarded a grant by the German Federal Ministry of Education and Research, BMBF.

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TB Alliance And DNDi Announce License Agreement

July 8, 2010 7:51 am | News | Comments

The Global Alliance for TB Drug Development (TB Alliance) and Drugs for Neglected Diseases initiative (DNDi) announced today a unique first-ever royalty-free license agreement between two not-for-profit drug developers that speeds progress toward markedly improved therapy of multiple neglected diseases.

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Histone Helps Form Ribosomes

July 8, 2010 7:33 am | News | Comments

A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes part in the formation of ribosomes, the cellular workbenches on which all proteins are made.

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