Strategies & Technologies Driving Drug Discovery to Market
A Model Dilemma
March 5, 2009 3:59 am | by Catherine Shaffer, Contributing Editor | Articles | CommentsCell-based toxicogenomics studies are emerging as an alternative to animal testing. But for now, animal models are the necessary choice.
Human vs. Rodent
March 5, 2009 3:37 am | by D. Lansing Taylor, PhD, Founder, President and CEO, Cellumen, Inc., Pittsburgh, PA. | Articles | CommentsIn vitro toxicity testing has been used for many years, but the predictive power for either rodent, or human toxic liability has not been demonstrated, until recently.
Court Ruling Could Hamper Drug Innovation
March 4, 2009 11:58 am | by Linda A. Johnson, AP Business Writer | News | CommentsA US Supreme Court ruling that federal approval of a drug is no protection from lawsuits in state courts could make drugmakers more cautious about safety issues and may lead them to halt development of some medicines.
Adventures in vivo
March 4, 2009 11:57 am | by James Netterwald, PhD, MT (ASCP), Senior Editor | Articles | CommentsIn vivo imaging technology developers and providers gear new features toward the drug discovery and development process.
Saving Time and Sample
March 4, 2009 11:29 am | by David Hayes, Director, Research and Development, Bioscience Division, Millipore Corporation | Articles | CommentsResearchers step up to multiplex bead-based platforms to detect proteins for target indentification through clinical analysis.
Helping Hands for Formulation
March 4, 2009 10:28 am | by Lindsay Hock, Associate Editor | Articles | CommentsWith a push to help clients get into the clinic faster and get their drugs on the market, contract formulators assist in all stages of the drug formulation process.
Genome Race Accelerates
March 4, 2009 9:39 am | by Rita C. Peters, Editor in Chief | Articles | CommentsIt took 13 years and nearly $3 billion to sequence the first single human genome, a proverbial lifetime and bank bailout away from the goal of a $1000 genome for an individual’s DNA sequence.
Next Leg in hESC Race
March 4, 2009 9:23 am | by Ted Agres, Contributing Editor | Articles | CommentsThe Food and Drug Administration’s (FDA) approval of a clinical trial involving a human embryonic stem cell-based therapy is being hailed both as a triumph of science over politics, as well as heralding a much-needed financial shot in the arm for the nascent hESC biotech industry.
Contract Formulation Company Profile - Lyophilization Services of New England
March 4, 2009 8:28 am | Articles | CommentsLyophilization Services of New England, Inc. (LSNE) has provided CGMP contract manufacturing services since 1997.
The Blind Mole Rat: A Soldier in the War on Cancer
March 4, 2009 8:03 am | News | CommentsA new discovery shows that cellular mechanisms used by the blind mole rat to survive the very low oxygen environment of its subterranean niche are the same as those that tumors use to thrive deep in our tissues.
Promising Target to Treat Chronic Abdominal Pain Uncovered
March 4, 2009 7:39 am | News | CommentsHigh levels of a protein linked to the way pain signals are sent to the brain led to a decrease in abdominal pain in a recent study in mice.
Is The FDA A Broken Agency?
March 4, 2009 6:36 am | by Ricardo Alonso-Zaldivar and Mike Baker, AP Writers | News | CommentsEvery few months, the Food and Drug Administration goes into fire-brigade mode, rushing to get control over another safety crisis.
Drug Development Program Based On CAP Human Cell Line
March 4, 2009 6:16 am | News | CommentsAlloksys Life Sciences BV, CEVEC Pharmaceuticals GmbH, and PharmaCell BV announced the start of Theraptech, a 2.4 million Euro therapeutic protein development program subsidized under the European Trans Bio Program.
Broccoli May Help Protect against Respiratory Conditions
March 4, 2009 6:01 am | News | CommentsUCLA researchers report that a naturally occurring compound found in broccoli and other cruciferous vegetables may help protect against respiratory inflammation that causes conditions like asthma.
Using Hair to Manage HIV/AIDS and Predict Treatment Success
March 4, 2009 5:43 am | News | CommentsUCSF researchers have found that examining levels of antiretroviral drugs in hair samples taken from HIV patients on therapy strongly predicts treatment success.
