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DDD Update

Daily news and top headlines for drug research professionals

Fetal Heart Cells Could Be Key to Renewing Cardiac Cells

October 8, 2010 7:01 am | News | Comments

Heart muscle cells do not normally replicate in adult tissue, but multiply with abandoned during development. This is why the loss of heart muscle after a heart attack is so dire—you can't grow enough new heart muscle to make up for the loss.

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Genomic and Metabolic Data Harnessed to Fight TB

October 8, 2010 6:49 am | News | Comments

Researchers at the Institute for Genomic Biology at the University of Illinois have developed a way to harness the prodigious quantities of both genomic and metabolic data being generated with high-throughput genomics and other techniques.

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An X-ray for Your Genes

October 8, 2010 6:45 am | News | Comments

Not every patient reacts to a medicine in the same way. The personal genetic characteristics of individuals and populations can explain why a specific prescription successfully treats one patient and not another.

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The Business of Recombinant Protein Production

October 7, 2010 11:05 am | by Joel White, Business Manager, Biotechnology; Ajinomoto AminoScience, Raleigh, North Carolina | Articles | Comments

The path to a functionally active recombinant pharmaceutical can be plagued with technical pitfalls and failures. Strategies can optimize use of time and resources.

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DNA Sequencing Kits

October 7, 2010 8:33 am | Product Releases | Comments

Bioo Scientific has expanded its line of kits for next generation sequencing sample preparation with the introduction of the AIR Genomic and AIR Paired-End DNA Sequencing Kits, designed for use with the llumina GAII and HiSeq 2000 sequencers.

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Mass Spectrometer

October 7, 2010 8:30 am | Product Releases | Comments

Thermo Fisher Scientific Inc. has announced the Thermo Scientific Prima PRO, a next-generation process massspectrometer for online gas analysis in biotechnology applications.

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Ricera Adds to Drug Safety Division

October 7, 2010 8:14 am | News | Comments

Ricerca Biosciences, a preclinical contract research organization (CRO) providing services to the biopharmaceutical industry, has announced the addition of Eric J. Lubert, Ph.D., as a scientist in its drug safety division.

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GSK Announces Singapore Collaborations

October 7, 2010 8:11 am | News | Comments

GlaxoSmithKline R&D announced the start of four new academic collaborations with Singapore-based scientists and GSK’s global drug discovery network as the first step in a longer term plan to seek alliances with scientific experts in the country.

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Insoluble Nanodrugs Can Still Be Absorbed

October 7, 2010 8:08 am | News | Comments

Researchers in India have demonstrated that producing nanoscopic crystals of a pharmaceutical product can allow the medication to be absorbed by the gut even if the drug is not soluble in water.

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Zebrafish Tumors Similar to Humans

October 7, 2010 8:00 am | News | Comments

While human cells have 23 pairs of chromosomes, tumor cells usually have extra copies of some chromosomes. This trait, known as aneuploidy, appears to give tumor cells a survival edge.

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FDA Admits Need to Modernize

October 7, 2010 7:55 am | by Matthew Perrone | News | Comments

The Food and Drug Administration must update its scientific tools for reviewing prescription drugs, medical devices and tracking food safety, according to a research plan laid out by agency leadership.

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Prescription Drug Sales May Increase 7%

October 7, 2010 7:53 am | by Linda A. Johnson | News | Comments

Revenue from global prescription drug sales should increase 5 percent to 7 percent next year, reaching at least $880 billion, fueled by new drugs and rising sales in developing countries, according to drug data firm IMS Health.

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Rituximab Shows Benefits in Untreated CLL

October 7, 2010 7:46 am | News | Comments

The monoclonal antibody rituximab given in addition to a standard chemotherapy regimen of fludarabine plus cyclophosphamide significantly prolongs the lives of patients with chronic lymphocytic leukaemia compared with standard chemotherapy alone.

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Sanofi Publishes Jevtana Data

October 7, 2010 7:41 am | News | Comments

The data demonstrated that Jevtana with prednisone reduced the risk of death by 30% in men with metastatic castration-resistant prostate cancer whose disease progressed following treatment with a docetaxel-containing treatment regimen.

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Amgen Announces Results of Phase 3 Studies

October 7, 2010 7:36 am | News | Comments

Amgen announced that results from the PRIME '203' and '181' pivotal Phase 3 trials evaluating Vectibix in combination with chemotherapy (FOLFOX or FOLFIRI) as a first and second-line treatment for metastatic colorectal cancer, respectively.

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