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DDD Update

Daily news and top headlines for drug research professionals

Folotyn Drives Allos Revenue Growth

January 13, 2011 5:46 am | News | Comments

Allos Therapeutics Inc. said that sales of the lymphoma drug Folotyn drove revenue in the fourth quarter and it will cut 13 percent of its staff. The company said it expects to report revenue of $11.7 million, which tops Wall Street estimates.


Genzyme Revenue Falls Short in 4Q

January 13, 2011 5:40 am | News | Comments

Genzyme Corp. said that it expects to report revenue growth in the fourth quarter, but the preliminary results fell short of expectations. The drugmaker also trimmed its outlook for 2011 as it continues recovering from manufacturing problems.


Watson Meets Earning Estimates

January 13, 2011 5:33 am | News | Comments

Watson Pharmaceuticals Inc. said Wednesday its 2010 results were about equal to its expectations. The company said its earnings will be at the midpoint of its estimated range of $3.37 to $3.45 per share.


Oregon Sues J & J Over Recall

January 13, 2011 5:30 am | News | Comments

Oregon Attorney General John Kroger has sued Johnson & Johnson and two subsidiaries, claiming consumers were exposed to defective supplies of Motrin by a delay in public disclosure of a recall.


FDA Panel Votes No on Liprotamase

January 13, 2011 5:27 am | News | Comments

Drugmaker Eli Lilly and Co. Inc. said a panel of federal health advisers voted against an experimental treatment designed to aid digestion in patients with cystic fibrosis and other diseases that affect the pancreas.


Cell Sorter

January 13, 2011 5:15 am | Product Releases | Comments

The MoFlo Astrios next-generation cell sorter from Beckman Coulter, Inc. leverages the stable fluidic design of the original MoFlo and the electronic processing of the MoFlo XDP.


LCD Microscope Display

January 13, 2011 5:11 am | Product Releases | Comments

Carl Zeiss introduced a new generation of ergonomic and compact tissue culture microscopes with its Primo Vert Monitor. The traditional eyepiece has been replaced with an integrated digital camera and LCD display.


Advanced Imaging Software for Western Blot Analysis

January 13, 2011 5:06 am | by Stephanie R. Noles, PhD, Global In Vitro Product Manager Carestream Molecular Imaging, Woodbridge, Conn. | Articles | Comments

Protein analysis has quickly become as integral a component of the drug discovery process as genomics. The examination of protein expression levels and post-translational modifications helps identify new drug targets.


Fluorescent Western Blotting: A Quantitative Approach

January 13, 2011 4:54 am | by Amy Schutz-Geschwender, PhD, Principal Scientist; LI-COR Biosciences, Lincoln, Neb. | Articles | Comments

For decades, researchers have used Western blotting to confirm the presence of a target protein in a complex sample. After gel electrophoresis, proteins are transferred to a membrane and interrogated with antibodies.


High Throughput Western Blotting

January 13, 2011 4:32 am | by Jeff Xu, Product Manager, Blotting and Stains, Bio-Rad Laboratories, Inc., Hercules, Calif. | Articles | Comments

Western blotting involves the transfer of proteins from a gel matrix to a membrane following protein electrophoresis. This process serves as a bridge between protein separation and identification.


QIAGEN Gains Minority Stake in Alacris

January 11, 2011 11:54 am | News | Comments

QIAGEN has signed an agreement for the acquisition of a strategic stake in Alacris Theranostics GmbH, a German start-up company using novel technologies to develop individualized cancer treatment strategies based upon a patient’s genomic profile.


Genzyme Quarterly Growth Falls Short

January 11, 2011 11:52 am | News | Comments

Genzyme Corp. said that it expects to report adjusted profit and revenue growth in the fourth quarter, but the preliminary results fell short of Wall Street expectations.


New Scoring System for PTEN Mutation

January 11, 2011 11:49 am | News | Comments

Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers.


Protective Protein Also Causes Atherosclerosis

January 11, 2011 11:47 am | News | Comments

UCLA researchers have found that a protein that plays an important role in some antioxidant therapies may not be as effective due to additional mechanisms that cause it to promote atherosclerosis, or clogging of the arteries.


3D Tissue Modeling System

January 11, 2011 11:43 am | Product Releases | Comments

The Automation Partnership (TAP) announced a new 12-well version of RAFT (Real Architecture for 3D Tissue), its system for generating reproducible, 3D collagen tissue models.



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