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DDD Update

Daily news and top headlines for drug research professionals

Vaccine Achieves Simultaneous Protection Against Ricin, Anthrax

July 10, 2014 12:00 pm | News | Comments

Soligenix Inc. announced that the combination of RiVax and VeloThrax induces protective immunity to both ricin toxin and anthrax toxin exposure. Read more...                           

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Tiny DNA Pyramids Enter Bacteria, Deliver Deadly Payload

July 10, 2014 12:00 pm | News | Comments

Bacterial infections usually announce themselves with pain and fever but often can be defeated with antibiotics— and then there are those that are sneaky and hard to beat. Now, scientists have built a new weapon against such pathogens in the form of tiny DNA pyramids. Read more...

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NIH Launches Phase 1 Trial of Novel C. Diff Drug

July 10, 2014 12:00 pm | News | Comments

The National Institute of Allergy and Infectious Diseases has launched an early-stage clinical trial of CRS3123, an investigational oral antibiotic intended to treat Clostridium difficile (C. difficile) infection. Read more...     

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Astellas Submits NDA for Life-Threatening Fungal Infection Drug

July 10, 2014 12:00 pm | News | Comments

Astellas announced it has submitted a New Drug Application to the FDA seeking approval for isavuconazole for the treatment of invasive aspergillosis and invasive mucormycosis. Read more...                 

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Review: Gaps Between Approval, Safety Assessment of ADHD Drugs

July 10, 2014 12:00 pm | News | Comments

Over the last 60 years, the FDA approved 20 medications for ADHD based on clinical trials that were not designed to study their long-term efficacy and safety or to detect rare adverse events, researchers report. Read more...        

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PerkinElmer Launches LabChip GX and GXII Touch

July 9, 2014 3:32 pm | Product Releases | Comments

PerkinElmer Inc., a global leader focused on the health and safety of people and the environment, announced the launch of the new LabChip GX Touch and GXII Touch automated electrophoresis systems. Read more...

Ario Kicks Off Efficacy Trial of Chronic Idiopathic Cough Drug

July 9, 2014 3:14 pm | News | Comments

Ario Pharma Ltd, the biopharmaceutical company developing innovative new treatments for respiratory disease, announced that it has commenced a Phase 2a study of its oral TRPV1 antagonist, XEN-D0501, for the treatment and prevention of cough in patients with chronic idiopathic cough. Read more...

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DelMar Receives Canadian Funding

July 9, 2014 3:09 pm | News | Comments

DelMar Pharmaceuticals Inc. announced that the company has been awarded a non-refundable financial contribution of up to CDN$194,000 from the National Research Council of Canada's Industrial Research Assistance Program (NRC-IRAP) to support personnel and research costs. Read more...

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Dezima Extends Clinical Development of Dyslipidemia Drug

July 9, 2014 3:02 pm | News | Comments

Dezima Pharma, the biotechnology company developing innovative drugs in the field of dyslipidemia, announced the approval of a Phase 1 pilot study in subjects with isolated, elevated Lipoprotein(a) (Lp(a)), for which additional funding has been secured. Read more...

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Domainex Reports Success of COPD Drug

July 9, 2014 2:57 pm | News | Comments

Domainex Ltd, a UK-based drug discovery company developing first-in-class small-molecule inhibitors of two closely-related pro-inflammatory kinases TBK1 and IKK-epsilon announced that its lead compound has demonstrated a more potent effect in a key model of COPD than either roflumulast or a p38 inhibitor. Read more...

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Arthritis Drug Misses New Indication Endpoint

July 9, 2014 2:51 pm | News | Comments

Shares of Celgene Corp. slipped in premarket trading Wednesday after the drugmaker said its psoriatic arthritis treatment Otezla missed the main goal of a late-stage study exploring an additional use in a painful spinal joint disorder called ankylosing spondylitis. Read more...

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EFPIA Denounces French Law on Off-label Drug Use

July 9, 2014 2:43 pm | News | Comments

EFPIA, the European Federation of Pharmaceutical Industries and Associations, criticized the intent of the French government to broadly enlarge the use of-off label drugs for economic reasons, even if there is an approved drug available. Read more...

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Baxter Snags First Drug Candidate from NIH Program

July 9, 2014 1:35 pm | News | Comments

A drug candidate developed by researchers at the NIH’s National Center for Advancing Translational Sciences (NCATS) and its collaborators to treat sickle cell disease has been acquired by Baxter International’s BioScience business. Read more...  

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Salix Pharma to Buy Cosmo Tech

July 9, 2014 1:26 pm | News | Comments

Shares of Salix Pharmaceuticals fell Wednesday before markets opened and a day after it announced plans to become the latest U.S. company to incorporate overseas and lower its taxes. Read more...               

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Governor Pushes for Trials of Marijuana Derivative

July 9, 2014 1:12 pm | by Christina A. Cassidy | News | Comments

Georgia's governor is pushing clinical trials for a marijuana-derived drug that proponents say could help treat severe seizure disorders among children. Read more...                         

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