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DDD Update

Daily news and top headlines for drug research professionals

Pfizer to Pay $35M to Settle Unapproved Use Case

August 7, 2014 10:34 am | News | Comments

Pfizer will pay $35 million to resolve allegations by 42 states that its subsidiary, Wyeth Pharmaceuticals, illegally marketed an organ transplant drug for unapproved uses, but did not admit any wrongdoing or liability as part of the settlement. Read more...

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Ebola Vaccine Antibodies Are Made in Tobacco Plants

August 7, 2014 10:27 am | News | Comments

Charlie Arntzen has worked tirelessly on new platforms to deliver drugs and focused on plant-based drug delivery systems, testing a wide range of plants as possible “manufacturing platforms” for therapeutics for the developing world. Read more...

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BDSI Reports 'Encouraging' Results from Phase 3 Analysis

August 6, 2014 3:31 pm | News | Comments

BioDelivery Sciences International Inc. announced that it has completed a pre-specified interim analysis of the ongoing initial pivotal Phase 3 trial for Clonidine Topical Gel for the treatment of painful diabetic neuropathy (PDN). Read more...  

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Cubist Recalls Some Cubicin Lots

August 6, 2014 3:25 pm | News | Comments

Cubist announced it is voluntarily recalling certain lots of Cubicin (daptomycin for injection) to the user level due to the potential presence of glass particulate matter in vials produced by a contract manufacturer. Read more...       

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Year-round Preventive Meds Reduce Malaria Risk in Young Children

August 6, 2014 3:20 pm | News | Comments

A year-round preventive drug treatment substantially reduces young children’s risk of contracting malaria and poses no serious risk of adverse events, according to a study. Read more...                   

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Aspirin Cuts Risk of Digestive Tract Cancers

August 6, 2014 3:07 pm | News | Comments

New research reveals that taking aspirin can significantly reduce the risk of developing– and dying from– the major cancers of the digestive tract, i.e. bowel, stomach and esophageal cancer. Read more...              

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New Drug Cures Arthritis in Mice

August 6, 2014 2:56 pm | News | Comments

With a new therapeutic product, researchers have managed to cure arthritis in mice for the first time. The scientists are now planning to test the efficacy of the drug in humans. Read more...                 

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Ebola Vaccine Won't Come Without Taking Some Risks

August 6, 2014 2:48 pm | News | Comments

The current West African Ebola virus outbreak, which has now reached more than 1,000 cases and resulted in more than 800 deaths, is a reminder of the often unpredictable nature of viruses and the difficulties in finding and developing vaccines and antivirals. Read more...

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Breaking News: Ebola Death Toll Reaches 932

August 6, 2014 11:58 am | by Bashir Adigun and Krista Larson, Associated Press | News | Comments

A Nigerian nurse who treated a man with Ebola is now dead and five others are sick with one of the world's most virulent diseases, authorities said Wednesday as the death toll rose to at least 932 people in four West African countries. Read more...

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Oxygen, Imperial College London Collaborate on Organ Failure Trial

August 6, 2014 10:56 am | News | Comments

Oxygen Biotherapeutics Inc. announced a collaboration with Imperial College London to provide supplemental funding to support the accelerated enrollment and completion of the ongoing LeoPARDS Trial awarded by the Efficacy and Mechanism Evaluation Programme and funded by the Medical Research Council and managed by the National Institute for Health Research. Read more...

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Psoriasis, RA Drug Shows Good Efficacy

August 6, 2014 10:45 am | News | Comments

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced new data from a retrospective analysis of its autoimmune disease advanced trials that shows high efficacy of its orally bioavailable drug CF101. Read more...

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Ventana Paves the Way for Companion Diagnostics in China

August 6, 2014 10:39 am | News | Comments

Ventana Medical Systems Inc., a member of the Roche Group, announced a new agreement with Quintiles Inc. to offer College of American Pathology-standard companion diagnostic testing services in China for pharmaceutical and biotech companies conducting early phase clinical trials. Read more...

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Cancer Cells Look for a Soft Bed

August 6, 2014 10:31 am | News | Comments

Cancer cells that break away from tumors to go looking for a new home may prefer to settle into a soft bed, according to new findings from researchers at the University of Illinois published in the journal Nature Communications. Read more...

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EU Approves Avastin for Ovarian Cancer

August 6, 2014 10:24 am | News | Comments

Roche announced that the European Commission approved the use of Avastin (bevacizumab) in combination with paclitaxel, topotecan, or pegylated liposomal doxorubicin chemotherapy as a treatment for women with recurrent ovarian cancer that is resistant to platinum-containing chemotherapy. Read more...

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Obama Seeks Executive Steps to Curb Tax Inversions

August 6, 2014 10:18 am | by Josh Lederman, Associated Press | News | Comments

Aiming to sidestep a logjam in Congress, the Obama administration is looking for steps it could take on its own to prevent American companies from reincorporating overseas to shirk U.S. taxes, officials said Tuesday in an election-year push that Democrats hope will appeal to middle-class voters. Read more...

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