Drug Discovery & Development

Strategies & Technologies Driving Drug Discovery to Market

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Daily news and top headlines for drug research professionals

Putting MicroRNA on Microarrays

December 28, 2007 6:21 am | by Mike May, Contributing Editor | Articles | Comments

Lab Automation Supplement: A variety of companies provide products and services that simplify studies in the growing area of gene regulation and potential therapy.

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What’s In a Cell?

December 28, 2007 5:36 am | by Angelo DePalma, Contributing Editor | Articles | Comments

Lab Automation Supplement: New technologies aid cell-based assays to come out from behind the shadow of animal testing.

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To Automate or Not to Automate?

December 27, 2007 4:15 pm | by Tanuja Koppal, PhD, Contributing Editor | Articles | Comments

Lab Automation Supplement: Knowing your needs—and what works—provides the answer for automation strategies in your proteomics lab.

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HTS Hits the Jackpot

December 27, 2007 10:03 am | by Alan Dove, Contributing Editor | Articles | Comments

Lab Automation Supplement: After a sometimes painful period of trial and error, high-throughput screeners have settled on a few winning classes of targets, with a special emphasis on kinases.

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No Room for Error

December 27, 2007 6:30 am | Articles | Comments

Accurate liquid handling removes uncertainty from high throughput screening applications.

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Pfizer Names Eliassen Group Strategic Supplier of the Year

December 20, 2007 11:46 am | News | Comments

Eliassen Group has received the 2007 Pfizer Development Operations' "Strategic Supplier Excellence Award."

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Firefly Genes Allow Testing of New Lymphoma Therapy

December 20, 2007 6:08 am | News | Comments

A firefly gene allows researchers to see just how effective a new drug combination actually is against some forms of cancer and its serious complication.

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Receptor Protein Key in Kidney Filtration Breakdown

December 20, 2007 4:39 am | News | Comments

Researchers identify a new molecular pathway that appears to be involved in urinary protein loss (proteinuria).

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Genetic Mutation Promotes Hardening of the Arteries

December 19, 2007 6:16 am | News | Comments

A genetic mutation expands lesions in the aorta and promotes coronary atherosclerosis, more commonly known as hardening of the arteries.

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New Strategy May Be Necessary For Protecting Against Infectious Diseases

December 18, 2007 9:43 am | News | Comments

Reseacrh identifies one actual process by which naïve T-cells are lost later in life.

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Breast Cancer Stem Cells in Mouse Tissue Identified and Repressed

December 18, 2007 8:59 am | News | Comments

By manipulating highly specific gene-regulating molecules called microRNAs, scientists at Cold Spring Harbor Laboratory report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue.

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Bacteria Causing Urinary Tract Infections Invade Bladder Cells

December 18, 2007 8:51 am | News | Comments

Scientists at Washington University School of Medicine in St. Louis have found proof that some of the bacteria that plague women with urinary tract infections (UTIs) are entrenched inside human bladder cells.

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Drug Combination Shrinks Breast Cancer Metastases in Brain

December 17, 2007 9:47 am | News | Comments

A combination of a targeted therapy and chemotherapy shrank metastatic brain tumors by at least 50 percent in one-fifth of patients with aggressive HER2-positive breast cancer.

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Magnetic Resonance Technique Reveals Insights Into Lung Disease

December 14, 2007 5:49 am | News | Comments

Doctors at the Universities of Nottingham and Leicester are collaborating in the use of a magnetic resonance technique to image and quantify the air spaces inside the lungs.

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Investigators Define Multi-step Pathway Allowing for Cell Survival and Death

December 14, 2007 5:27 am | News | Comments

A new study by researchers at the University of Massachusetts Medical School (UMMS) gained new insights into autophagy by studying the salivary gland cells of the fruit fly.

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